|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 115 out of 115 for Lsm8

<< First    < Previous  |  Next >    Last >>
0.009s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
Q9CRP6
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: true
•
•
•
•
•
Protein Domain
IPR044642 | PTHR15588
Type: Family
Description: This entry represents Sm-like protein Lsm1 and Lsm8. Lsm8 is found in the nuclear Lsm2-8 complex, which associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). The Lsm2-8 complex binds and stabilizes the 3'-terminal poly(U) tract of U6 snRNA and facilitates the assembly of U4-U6 di-snRNP and U4-U6-U5 tri-snRNP [, , ].Lsm1 can be found in the cytoplasmic Lsm1-7 complex, which associates with deadenylated mRNA and promotes decapping in the 5'-3' mRNA decay pathway [, ]. The Sm and the Lsm proteins, characterised by the Sm-domain, have RNA-related functions. The Sm heptamer ring associates with four (U1, U2, U4, U5) snRNPs, while Lsm2-8 heptamer is part of the U6 snRNP. Another Lsm heptameric complex, Lsm1-7, which differs from Lsm2-8 by one Lsm protein, functions in mRNA decapping, a crucial step in the mRNA degradation pathway [].
•
•
•
•
•
Protein
P62313
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
•
•
•
•
•
Protein
Q542U7
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
•
•
•
•
•
Protein
Q8VC85
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
•
•
•
•
•
Protein
P62307
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
•
•
•
•
•
Protein
Q544C9
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
•
•
•
•
•
Protein
A0A1B0GR26
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: false
•
•
•
•
•
Protein
Q3UX80
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
•
•
•
•
•
Protein
Q6NZQ3
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
•
•
•
•
•
Protein
Q497K3
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
•
•
•
•
•
Publication
10801455 | -
First Author: He W
Year: 2000
Journal: Curr Opin Cell Biol
Title: Functions of Lsm proteins in mRNA degradation and splicing.
Volume: 12
Issue: 3
Pages: 346-50
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•
Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
•
•
•
•
•
Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom