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Search results 101 to 115 out of 115 for Lsm8

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Type Details Score
Protein
Q9CRP6
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: true
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Protein Domain
IPR044642 | PTHR15588
Type: Family
Description: This entry represents Sm-like protein Lsm1 and Lsm8. Lsm8 is found in the nuclear Lsm2-8 complex, which associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). The Lsm2-8 complex binds and stabilizes the 3'-terminal poly(U) tract of U6 snRNA and facilitates the assembly of U4-U6 di-snRNP and U4-U6-U5 tri-snRNP [, , ].Lsm1 can be found in the cytoplasmic Lsm1-7 complex, which associates with deadenylated mRNA and promotes decapping in the 5'-3' mRNA decay pathway [, ]. The Sm and the Lsm proteins, characterised by the Sm-domain, have RNA-related functions. The Sm heptamer ring associates with four (U1, U2, U4, U5) snRNPs, while Lsm2-8 heptamer is part of the U6 snRNP. Another Lsm heptameric complex, Lsm1-7, which differs from Lsm2-8 by one Lsm protein, functions in mRNA decapping, a crucial step in the mRNA degradation pathway [].
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Protein
P62313
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
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Protein
Q542U7
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
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Protein
Q8VC85
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
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Protein
P62307
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein
Q544C9
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: false
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Protein
A0A1B0GR26
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: false
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Protein
Q3UX80
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein
Q6NZQ3
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
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Protein
Q497K3
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Publication
10801455 | -
First Author: He W
Year: 2000
Journal: Curr Opin Cell Biol
Title: Functions of Lsm proteins in mRNA degradation and splicing.
Volume: 12
Issue: 3
Pages: 346-50
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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