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Search results 101 to 147 out of 147 for Maf1

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Type Details Score
Publication
30110641 | -
First Author: Chen CY
Year: 2018
Journal: Cell Rep
Title: Maf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation.
Volume: 24
Issue: 7
Pages: 1852-1864
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Allele
Maf1<em1Smoc> | MGI:7290930
Name: MAF1 homolog, negative regulator of RNA polymerase III; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Gene
470929 | LOC470929
Type: gene
Organism: chimpanzee
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Gene
406750 | maf1a
Type: gene
Organism: zebrafish
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Gene
569875 | maf1b
Type: gene
Organism: zebrafish
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Gene
100426973 | LOC100426973
Type: gene
Organism: macaque, rhesus
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Strain
MGI:7718139 | C57BL/6JSmoc-Maf1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR038564 | Maf1_sf
Type: Homologous_superfamily
Description: Maf1 is a negative regulator of RNA polymerase III [, ]. It inhibits the de novo assembly of TFIIIB onto DNA []. Maf1 represses Pol III in response to DNA damage, oxidative stress, growth to stationary phase, treatment with rapamycin or chlorpromazine, and blocking of the secretory pathway []. It targets the initiation factor TFIIIB []. Its structure is composed of a central five-stranded antiparallel β-sheet that is flanked by one helix on one side and three helices on the other [].
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Gene
380400 | maf1.L
Type: gene
Organism: frog, African clawed
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Strain
MGI:5661502 | C57BL/6J-Maf1<em1Lnh>/J
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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HT Experiment
E-GEOD-65976 | RNA-seq analysis of epididymal adipose tissue from wild-type and Maf1 knockout mice
Series Id: GSE65976
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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UniProt Feature
UniProt Feature
Begin: 1
Description: Repressor of RNA polymerase III transcription MAF1 homolog
Type: chain
End: 258
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HT Experiment
GSE224743 | Contrasting effects of whole-body and hepatocyte-specific deletion of the RNA polymerase III repressor Maf1 in the mouse [RNA-Seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Maf1<+> | MGI:3575408
   
Name: MAF1 homolog, negative regulator of RNA polymerase III; wild type
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Allele
Maf1<tm1.1Lnh> | MGI:4837337
Name: MAF1 homolog, negative regulator of RNA polymerase III; targeted mutation 1.1, Nouria Hernandez
Allele Type: Targeted
Attribute String: Null/knockout
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Protein
P54841
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Allele
Maf1<tm1a(KOMP)Wtsi> | MGI:4420076
Name: MAF1 homolog, negative regulator of RNA polymerase III; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Genotype
Genotype
Symbol: Maf1/Maf1
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Maf1/Maf1
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Publication
16231153 | -
First Author: Patel S
Year: 2005
Journal: Planta
Title: The plant nuclear envelope protein MAF1 has an additional location at the Golgi and binds to a novel Golgi-associated coiled-coil protein.
Volume: 222
Issue: 6
Pages: 1028-40
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Allele
Tg(RP24-173I23)1Sun | MGI:3801155
Name: transgene insertion 1, John Sundberg
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Maf1/Maf1 Speer6-ps1/Speer6-ps1<+>
Background: involves: C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Strain
MGI:3805774 | FVB/NJ-Tg(RP24-173I23)1Sun/Sun
Attribute String: coisogenic, transgenic
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Genotype
Genotype
Symbol: Tg(RP24-173I23)1Sun/?
Background: FVB/NJ-Tg(RP24-173I23)1Sun/Sun
Zygosity: ot
Has Mutant Allele: true
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Publication
22348129 | J:185326
First Author: Wang Z
Year: 2012
Journal: PLoS One
Title: SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells.
Volume: 7
Issue: 2
Pages: e31809
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Genotype
Genotype
Symbol: Sharpin/Sharpin Tg(RP24-173I23)1Sun/?
Background: involves: C57BL/KaLawRij * FVB/NJ
Zygosity: cx
Has Mutant Allele: true
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Publication
17538631 | J:121810
First Author: Seymour RE
Year: 2007
Journal: Genes Immun
Title: Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.
Volume: 8
Issue: 5
Pages: 416-21
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Publication
14680841 | J:86942
First Author: Kajihara M
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter.
Volume: 312
Issue: 3
Pages: 831-42
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Publication
28341772 | J:301759
First Author: Mange F
Year: 2017
Journal: Genome Res
Title: Diurnal regulation of RNA polymerase III transcription is under the control of both the feeding-fasting response and the circadian clock.
Volume: 27
Issue: 6
Pages: 973-984
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Publication
20417281 | J:164270
First Author: Smith KR
Year: 2010
Journal: Mol Cell Neurosci
Title: Identification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neurons.
Volume: 44
Issue: 4
Pages: 330-41
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Publication
12397079 | -
First Author: Pardo PS
Year: 2002
Journal: J Biol Chem
Title: MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation.
Volume: 277
Issue: 52
Pages: 50860-6
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Protein Domain
IPR038011 | MRG15
Type: Family
Description: Mortality factor 4-like protein 1 (MORF4L1 or MRG15) is a transcription factor and a chromodomain protein. It is a component of the NuA4 histone acetyltransferase complex [], the Sin3 complex which acts to repress transcription by deacetylation of nucleosomal histones [], and the nuclear protein complexes MAF1 and MAF2 []. MRG15 also interacts with the BRCA complex, especially with subunit PALB2 []. MRG15 has an MRG domain in its C-terminal region, which interacts with the nucleoprotein PAM14 during transcriptional regulation [].The NuA4 histone acetyltransferase complex (also known as the TRRAP/TIP60-containing histone acetyltransferase complex) acetylates nucleosomal histones H4 and H2A thereby activating selected genes for transcription and is a a key regulator of transcription, cellular response to DNA damage and cell cycle control []. In yeast, where the complex was first identified, NuA4 consists of at least ACT1, ARP4, YAF9, VID21, SWC4, EAF3, EAF5, EAF6, EAF7, EPL1, ESA1, TRA1 and YNG2 []. In humans, the complex is composed of the histone acetyltransferase KAT5 (also known as TIP60) plus the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, MAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6 [].
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Publication
20332121 | -
First Author: Hayakawa T
Year: 2010
Journal: J Cell Sci
Title: MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.
Volume: 123
Issue: Pt 7
Pages: 1124-30
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Publication
17008723 | -
First Author: Zhang P
Year: 2006
Journal: Protein Sci
Title: The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14.
Volume: 15
Issue: 10
Pages: 2423-34
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Protein
A0A087WQ34
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Protein
Q5DTS9
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Protein
Q3U5J6
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
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Protein
P60762
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: false
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Protein
Q569V4
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
A0A087WQB0
Organism: Mus musculus/domesticus
Length: 296  
Fragment?: false
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Protein
Q3UBK1
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
Q3UIS6
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: true
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Publication
14966270 | J:320265
First Author: Doyon Y
Year: 2004
Journal: Mol Cell Biol
Title: Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.
Volume: 24
Issue: 5
Pages: 1884-96
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Publication
15045029 | -
First Author: Kobor MS
Year: 2004
Journal: PLoS Biol
Title: A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.
Volume: 2
Issue: 5
Pages: E131
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Publication
15196461 | -
First Author: Doyon Y
Year: 2004
Journal: Curr Opin Genet Dev
Title: The highly conserved and multifunctional NuA4 HAT complex.
Volume: 14
Issue: 2
Pages: 147-54
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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