Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
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•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
MAP1S heavy chain |
Type: |
chain |
End: |
742 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
743 |
Description: |
MAP1S light chain |
Type: |
chain |
End: |
973 |
|
•
•
•
•
•
|
Component |
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•
•
•
•
•
|
Component |
|
•
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•
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•
|
Publication |
First Author: |
Liu L |
Year: |
2009 |
Journal: |
Cell Oncol |
Title: |
Dual function microtubule- and mitochondria-associated proteins mediate mitotic cell death. |
Volume: |
31 |
Issue: |
5 |
Pages: |
393-405 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
MAP1-family proteins are microtubule-associated proteins (MAPs) that bind along the microtubule lattice. Mammalian genomes usually contain three family members, MAP1A, MAP1B and MAP1S. Only one family member, Futsch, is found in Drosophila.Human MAP1A and MAP1B, are predominantly expressed in neurons, where they are thought to be important in the formation and development of axons and dendrites []. Human MAP1A and MAP1B stabilise microtubules and interact with other cellular components, including filamentous actin and signaling proteins. The activity of MAP1A and MAP1B is controlled by upstream signaling mechanisms, including the MAP kinase and glycogen synthase kinase-3 beta pathways []. Human MAP1S is a heterodimer with a heavy and a light chain. Both MAP1S heavy and light chains interact with microtubules, while MAP1S light chain interacts with actin []. MAP1S is involved in the formation of microtubule bundles []. It mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD) []. It bridges autophagic components with microtubules and mitochondria plays a role in apoptosis [, , ]. |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
528
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
236
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
396
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
324
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
61
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
377
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
691
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
724
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Halpain S |
Year: |
2006 |
Journal: |
Genome Biol |
Title: |
The MAP1 family of microtubule-associated proteins. |
Volume: |
7 |
Issue: |
6 |
Pages: |
224 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2776
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2464
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2464
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
3014
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Eriksson M |
Year: |
2010 |
Journal: |
Neurosci Lett |
Title: |
MAP1B binds to the NMDA receptor subunit NR3A and affects NR3A protein concentrations. |
Volume: |
475 |
Issue: |
1 |
Pages: |
33-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baltussen LL |
Year: |
2018 |
Journal: |
EMBO J |
Title: |
Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics. |
Volume: |
37 |
Issue: |
24 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li W |
Year: |
2019 |
Journal: |
Cell Death Differ |
Title: |
Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation. |
Volume: |
26 |
Issue: |
8 |
Pages: |
1379-1395 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li W |
Year: |
2020 |
Journal: |
Oncogene |
Title: |
LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas. |
Volume: |
39 |
Issue: |
19 |
Pages: |
3879-3892 |
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