Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:28298 |
Assay Type: |
RNA in situ |
Annotation Date: |
1998-11-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1617718 |
Pattern: |
Regionally restricted |
Stage: |
TS18 |
Assay Id: |
MGI:1309400 |
Age: |
embryonic day 11.0 |
|
Note: |
Expression is in the pre-thoracic muscles. |
Specimen Label: |
Not Shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:28298 |
Assay Type: |
RNA in situ |
Annotation Date: |
1998-11-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1618418 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:1309400 |
Age: |
embryonic day 11.0 |
|
|
Specimen Label: |
Not Shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Voss AK |
Year: |
1998 |
Journal: |
Dev Dyn |
Title: |
Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing. |
Volume: |
212 |
Issue: |
2 |
Pages: |
258-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mangan ME |
Year: |
1996 |
Journal: |
Mamm Genome |
Title: |
The gene for microtubule-associated protein 4 (Mtap4) maps to the distal region of mouse chromosome 9. |
Volume: |
7 |
Issue: |
12 |
Pages: |
918-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sumigray KD |
Year: |
2012 |
Journal: |
J Cell Biol |
Title: |
Noncentrosomal microtubules and type II myosins potentiate epidermal cell adhesion and barrier formation. |
Volume: |
199 |
Issue: |
3 |
Pages: |
513-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schrick JJ |
Year: |
2001 |
Journal: |
Gene |
Title: |
cDNA cloning, mapping and expression of the mouse propionyl CoA carboxylase beta (pccb), the gene for human type II propionic acidaemia. |
Volume: |
264 |
Issue: |
1 |
Pages: |
147-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
González-Billault C |
Year: |
2000 |
Journal: |
Mol Cell Neurosci |
Title: |
Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels. |
Volume: |
16 |
Issue: |
4 |
Pages: |
408-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wittenburg H |
Year: |
2002 |
Journal: |
Physiol Genomics |
Title: |
Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice. |
Volume: |
8 |
Issue: |
1 |
Pages: |
67-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho KI |
Year: |
2003 |
Journal: |
Comp Med |
Title: |
Fine mapping of the circling (cir) gene on the distal portion of mouse chromosome 9. |
Volume: |
53 |
Issue: |
6 |
Pages: |
642-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Argent L |
Year: |
2020 |
Journal: |
J Biol Chem |
Title: |
Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology. |
Volume: |
295 |
Issue: |
36 |
Pages: |
12716-12726 |
|
•
•
•
•
•
|
Publication |
First Author: |
Makeyev EV |
Year: |
2007 |
Journal: |
Mol Cell |
Title: |
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. |
Volume: |
27 |
Issue: |
3 |
Pages: |
435-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hezel AF |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. |
Volume: |
28 |
Issue: |
7 |
Pages: |
2414-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Munton RP |
Year: |
2007 |
Journal: |
Mol Cell Proteomics |
Title: |
Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. |
Volume: |
6 |
Issue: |
2 |
Pages: |
283-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
microtubule-associated protein 4; endonuclease-mediated mutation 1, Yuesheng Huang |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1060
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bos PH |
Year: |
2019 |
Journal: |
Cell Chem Biol |
Title: |
Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents. |
Volume: |
26 |
Issue: |
12 |
Pages: |
1703-1715.e37 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics. |
|
•
•
•
•
•
|
Publication |
First Author: |
Punga T |
Year: |
2003 |
Journal: |
FEBS Lett |
Title: |
Adenovirus 2 E1B-55K protein relieves p53-mediated transcriptional repression of the survivin and MAP4 promoters. |
Volume: |
552 |
Issue: |
2-3 |
Pages: |
214-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sharifmoghadam MR |
Year: |
2008 |
Journal: |
Mol Microbiol |
Title: |
The Schizosaccharomyces pombe Map4 adhesin is a glycoprotein that can be extracted from the cell wall with alkali but not with beta-glucanases and requires the C-terminal DIPSY domain for function. |
Volume: |
69 |
Issue: |
6 |
Pages: |
1476-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Illenberger S |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics. |
Volume: |
271 |
Issue: |
18 |
Pages: |
10834-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chao C |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage. |
Volume: |
19 |
Issue: |
18 |
Pages: |
4967-75 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
The DIPSY domain is characterised by the distinctive D*I*PSY motif at the very C terminus of yeast cell-wall glycoproteins. It appears not to be conserved in any other species, however. In fungi, cell adhesion is required for flocculation, mating and virulence, and is mediated by covalently bound cell wall proteins termed adhesins. Map4, an adhesin required for mating in Schizosaccharomyces pombe, is N-glycosylated and O-glycosylated, and is an endogenous substrate for the mannosyl transferase Oma4p. Map4 has a modular structure with an N-terminal signal peptide, a serine and threonine (S/T)-rich domain that includes nine repeats of 36 amino acids (rich in serine and threonine residues, but lacking glutamines), and a C-terminal DIPSY domain with no glycosyl-phosphatidyl inositol (GPI)-anchor signal. The N-terminal S/T-rich regions, are required for cell wall attachment, but the C-terminal DIPSY domain is required for agglutination and mating in liquid and solid media []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Murphy M |
Year: |
1996 |
Journal: |
Genes Dev |
Title: |
Wild-type p53 negatively regulates the expression of a microtubule-associated protein. |
Volume: |
10 |
Issue: |
23 |
Pages: |
2971-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fassett JT |
Year: |
2013 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
AMPK attenuates microtubule proliferation in cardiac hypertrophy. |
Volume: |
304 |
Issue: |
5 |
Pages: |
H749-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Charoenvit Y |
Year: |
1997 |
Journal: |
Infect Immun |
Title: |
Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B-cell epitopes. |
Volume: |
65 |
Issue: |
8 |
Pages: |
3430-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Larhammar M |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons. |
Volume: |
37 |
Issue: |
46 |
Pages: |
11074-11084 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang CC |
Year: |
1999 |
Journal: |
Cancer Res |
Title: |
DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4. |
Volume: |
59 |
Issue: |
15 |
Pages: |
3663-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chapin SJ |
Year: |
1995 |
Journal: |
Biochemistry |
Title: |
Differential expression of alternatively spliced forms of MAP4: a repertoire of structurally different microtubule-binding domains. |
Volume: |
34 |
Issue: |
7 |
Pages: |
2289-301 |
|
•
•
•
•
•
|