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| First Author: |
Varin A |
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2010 |
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Blood |
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Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. |
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115 |
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2 |
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353-62 |
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Di Marco Barros R |
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2016 |
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Cell |
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Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. |
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167 |
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Court N |
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2010 |
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J Immunol |
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Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection. |
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184 |
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12 |
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7057-70 |
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Kang TB |
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2018 |
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Cell Death Differ |
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Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. |
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25 |
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6 |
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| Transgene |
| Type: |
transgene |
| Organism: |
mouse, laboratory |
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| Transgene |
| Type: |
transgene |
| Organism: |
mouse, laboratory |
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•
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Bonilla DL |
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2013 |
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Immunity |
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Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. |
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39 |
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Di Marco G |
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2024 |
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Cell Death Dis |
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The mitochondrial ATP-dependent potassium channel (mitoK(ATP)) controls skeletal muscle structure and function. |
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15 |
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1 |
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58 |
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•
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Di Marco E |
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2014 |
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Diabetologia |
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Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune-inflammatory responses in diabetic Apoe(-/-) mice. |
| Volume: |
57 |
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3 |
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633-42 |
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Marco EJ |
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2009 |
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BMJ Case Rep |
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ARHGEF9 disruption in a female patient is associated with X linked mental retardation and sensory hyperarousal. |
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2009 |
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Iwama A |
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1998 |
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Nucleic Acids Res |
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Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha. |
| Volume: |
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12 |
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Xue L |
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2013 |
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BMC Genomics |
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Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis. |
| Volume: |
14 |
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568 |
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MGD Nomenclature Committee |
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1995 |
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Nomenclature Committee Use |
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•
•
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Shanghai Model Organisms Center |
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2017 |
| Journal: |
MGI Direct Data Submission |
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Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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Mouse Genome Database and National Center for Biotechnology Information |
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Bairoch A |
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Mouse Genome Informatics Scientific Curators |
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2005 |
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Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
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| First Author: |
Mouse Genome Informatics Scientific Curators |
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2005 |
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Obtaining and loading genome assembly coordinates from NCBI annotations |
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International Knockout Mouse Consortium |
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2014 |
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Database Download |
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MGI download of modified allele data from IKMC and creation of new knockout alleles |
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Lennon G |
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WashU-HHMI Mouse EST Project |
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| First Author: |
Velocigene |
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2008 |
| Journal: |
MGI Direct Data Submission |
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Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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International Mouse Strain Resource |
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2014 |
| Journal: |
Database Download |
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MGI download of germline transmission data for alleles from IMSR strain data |
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| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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2014 |
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Database Release |
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Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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| First Author: |
Helmholtz Zentrum Muenchen GmbH |
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2010 |
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MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
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MGI Sequence Curation Reference |
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Carninci P |
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2005 |
| Journal: |
Science |
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The transcriptional landscape of the mammalian genome. |
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Adams DJ |
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2024 |
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Nature |
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Genetic determinants of micronucleus formation in vivo. |
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8002 |
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GemPharmatech |
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2020 |
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Cyagen Biosciences Inc. |
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| First Author: |
UniProt-GOA |
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2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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| First Author: |
GOA curators |
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2016 |
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Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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The Jackson Laboratory Mouse Radiation Hybrid Database |
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Database Release |
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Mouse T31 Radiation Hybrid Data Load |
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Diez-Roux G |
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2011 |
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PLoS Biol |
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A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
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e1000582 |
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Mouse Genome Informatics Scientific Curators |
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2010 |
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Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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MGI Genome Annotation Group and UniGene Staff |
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2015 |
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Database Download |
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MGI-UniGene Interconnection Effort |
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Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
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2010 |
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Annotation inferences using phylogenetic trees |
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| First Author: |
Allen Institute for Brain Science |
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Allen Brain Atlas: mouse riboprobes |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
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Database Download |
| Title: |
Consensus CDS project |
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| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
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Database Procedure |
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Automatic Encodes (AutoE) Reference |
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Mouse Genome Informatics |
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2010 |
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Database Release |
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Protein Ontology Association Load. |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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De Marco C |
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Mol Cancer Ther |
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The T197A Knock-in Model of Cdkn1b Gene to Study the Effects of p27 Restoration In Vivo. |
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2 |
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Ojala JR |
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2007 |
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J Biol Chem |
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Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition. |
| Volume: |
282 |
| Issue: |
22 |
| Pages: |
16654-66 |
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•
•
•
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•
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| Transgene |
| Type: |
transgene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
1 |
| Description: |
Macrophage receptor MARCO |
| Type: |
chain |
| End: |
518 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
de Marco MC |
| Year: |
2002 |
| Journal: |
J Cell Biol |
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MAL2, a novel raft protein of the MAL family, is an essential component of the machinery for transcytosis in hepatoma HepG2 cells. |
| Volume: |
159 |
| Issue: |
1 |
| Pages: |
37-44 |
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•
•
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Oizumi H |
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2023 |
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iScience |
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Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout. |
| Volume: |
26 |
| Issue: |
10 |
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Bi E |
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2018 |
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J Clin Invest |
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E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs. |
| Volume: |
128 |
| Issue: |
11 |
| Pages: |
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•
•
•
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| Publication |
| First Author: |
Crother TR |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Plasmacytoid dendritic cells play a role for effective innate immune responses during Chlamydia pneumoniae infection in mice. |
| Volume: |
7 |
| Issue: |
10 |
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e48655 |
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•
•
•
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| First Author: |
Rowland SL |
| Year: |
2014 |
| Journal: |
J Exp Med |
| Title: |
Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model. |
| Volume: |
211 |
| Issue: |
10 |
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•
•
•
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| First Author: |
De Marco V |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
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Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing. |
| Volume: |
106 |
| Issue: |
47 |
| Pages: |
19807-12 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
518
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
123
 |
| Fragment?: |
true |
|
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•
•
•
•
|
| Publication |
| First Author: |
Stefan KL |
| Year: |
2017 |
| Journal: |
PLoS One |
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Type I interferon signaling restrains IL-10R+ colonic macrophages and dendritic cells and leads to more severe Salmonella colitis. |
| Volume: |
12 |
| Issue: |
11 |
| Pages: |
e0188600 |
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•
•
•
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| First Author: |
Ah Kioon MD |
| Year: |
2018 |
| Journal: |
Sci Transl Med |
| Title: |
Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8. |
| Volume: |
10 |
| Issue: |
423 |
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•
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| First Author: |
Swiecki M |
| Year: |
2014 |
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J Immunol |
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Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells. |
| Volume: |
192 |
| Issue: |
9 |
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4409-16 |
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| First Author: |
Humbert M |
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2018 |
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Cancer Res |
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Intratumoral CpG-B Promotes Antitumoral Neutrophil, cDC, and T-cell Cooperation without Reprograming Tolerogenic pDC. |
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78 |
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12 |
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3280-3292 |
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| First Author: |
Horiuchi M |
| Year: |
2024 |
| Journal: |
Acta Neuropathol Commun |
| Title: |
ALS-linked mutant TDP-43 in oligodendrocytes induces oligodendrocyte damage and exacerbates motor dysfunction in mice. |
| Volume: |
12 |
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| First Author: |
Rahman T |
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2019 |
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Front Immunol |
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Plasmacytoid Dendritic Cells Provide Protection Against Bacterial-Induced Colitis. |
| Volume: |
10 |
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Ni H |
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Nat Commun |
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Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice. |
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15 |
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Kimura T |
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Commun Biol |
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Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice. |
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Blood |
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Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. |
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PLoS Pathog |
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| Publication |
| First Author: |
Di Domizio J |
| Year: |
2020 |
| Journal: |
Nat Immunol |
| Title: |
The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin. |
| Volume: |
21 |
| Issue: |
9 |
| Pages: |
1034-1045 |
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| Publication |
| First Author: |
Winkler ES |
| Year: |
2020 |
| Journal: |
Cell |
| Title: |
The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis. |
| Volume: |
182 |
| Issue: |
4 |
| Pages: |
901-918.e18 |
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| Publication |
| First Author: |
Yoshimatsu M |
| Year: |
2004 |
| Journal: |
Int J Exp Pathol |
| Title: |
Induction of macrophage scavenger receptor MARCO in nonalcoholic steatohepatitis indicates possible involvement of endotoxin in its pathogenic process. |
| Volume: |
85 |
| Issue: |
6 |
| Pages: |
335-43 |
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| Publication |
| First Author: |
Yu X |
| Year: |
2016 |
| Journal: |
Immunity |
| Title: |
Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
1093-1107 |
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| Allele |
| Name: |
macrophage receptor with collagenous structure; targeted mutation 1, Karl Tryggvason |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
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| Publication |
| First Author: |
Shah D |
| Year: |
2021 |
| Journal: |
Oncoimmunology |
| Title: |
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
1939601 |
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| Publication |
| First Author: |
Chu T |
| Year: |
2019 |
| Journal: |
J Immunol |
| Title: |
Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells. |
| Volume: |
202 |
| Issue: |
9 |
| Pages: |
2529-2534 |
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| Publication |
| First Author: |
Leylek R |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. |
| Volume: |
29 |
| Issue: |
11 |
| Pages: |
3736-3750.e8 |
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| Allele |
| Name: |
macrophage receptor with collagenous structure; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence |
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| Publication |
| First Author: |
Simankova A |
| Year: |
2021 |
| Journal: |
Glia |
| Title: |
Ddx20, DEAD box helicase 20, is essential for the differentiation of oligodendrocyte and maintenance of myelin gene expression. |
| Volume: |
69 |
| Issue: |
11 |
| Pages: |
2559-2574 |
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| Publication |
| First Author: |
Moro-Sibilot L |
| Year: |
2016 |
| Journal: |
Eur J Immunol |
| Title: |
Plasmacytoid dendritic cells are dispensable for noninfectious intestinal IgA responses in vivo. |
| Volume: |
46 |
| Issue: |
2 |
| Pages: |
354-9 |
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| Publication |
| First Author: |
Kang MJ |
| Year: |
2020 |
| Journal: |
Front Immunol |
| Title: |
IL-10 Protects Mice From the Lung Infection of Acinetobacter baumannii and Contributes to Bacterial Clearance by Regulating STAT3-Mediated MARCO Expression in Macrophages. |
| Volume: |
11 |
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| Pages: |
270 |
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| Publication |
| First Author: |
Niwa-Kawakita M |
| Year: |
2000 |
| Journal: |
Genesis |
| Title: |
Targeted expression of Cre recombinase to myelinating cells of the central nervous system in transgenic mice. |
| Volume: |
26 |
| Issue: |
2 |
| Pages: |
127-9 |
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| Publication |
| First Author: |
Biswas M |
| Year: |
2015 |
| Journal: |
Blood |
| Title: |
Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg. |
| Volume: |
125 |
| Issue: |
19 |
| Pages: |
2937-47 |
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