| Type |
Details |
Score |
| Publication |
| First Author: |
Sunkara KP |
| Year: |
2018 |
| Journal: |
Biomed Pharmacother |
| Title: |
Functional relevance of SATB1 in immune regulation and tumorigenesis. |
| Volume: |
104 |
|
| Pages: |
87-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frömberg A |
| Year: |
2018 |
| Journal: |
Cancer Lett |
| Title: |
The Special AT-rich Sequence Binding Protein 1 (SATB1) and its role in solid tumors. |
| Volume: |
417 |
|
| Pages: |
96-111 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry includes SATB1/2 from animals. SATB1 is a global gene regulator that acts as a "docking site"for several chromatin remodeling enzymes and recruits corepressors (HDACs) or coactivators (HATs) directly to promoters []. SATB1 can bind DNA specifically to the consensus SATB1-binding sequence (CSBS) consisting of two 5'-TAATA-3' half-sites that are arranged as inverted repeats flanking a central cytosine or guanine. It can also bind DNA non-specifically []. SATB1 has been shown to bind to the nuclear matrix attachment regions (MARs) of the immunoglobulin heavy chain intronic enhancer [], while SATB2 has been shown to bind to the MARs of the endogenous immunoglobulin micro locus in pre-B cells and enhances gene expression [].SATB1 is an identified oncogene, its increased expression is associated with poor prognosis in many cancers []. Mutations in the SATB2 gene cause SATB2-associated syndrome (SAS), characterised by developmental delay/intellectual disability with absent or limited speech development, craniofacial abnormalities, behavioral problems, dysmorphic features, and palatal and dental abnormalities [, ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang J |
| Year: |
2016 |
| Journal: |
Life Sci Space Res (Amst) |
| Title: |
Lessons learned using different mouse models during space radiation-induced lung tumorigenesis experiments. |
| Volume: |
9 |
|
| Pages: |
48-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wiersma EJ |
| Year: |
1999 |
| Journal: |
J Biol Chem |
| Title: |
Role of the intronic elements in the endogenous immunoglobulin heavy chain locus. Either the matrix attachment regions or the core enhancer is sufficient to maintain expression. |
| Volume: |
274 |
| Issue: |
8 |
| Pages: |
4858-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martins RP |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Nuclear matrix interactions at the human protamine domain: a working model of potentiation. |
| Volume: |
279 |
| Issue: |
50 |
| Pages: |
51862-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Purbowasito W |
| Year: |
2004 |
| Journal: |
DNA Res |
| Title: |
Large-scale identification and mapping of nuclear matrix-attachment regions in the distal imprinted domain of mouse chromosome 7. |
| Volume: |
11 |
| Issue: |
6 |
| Pages: |
391-407 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chavali PL |
| Year: |
2011 |
| Journal: |
Nucleic Acids Res |
| Title: |
Cis-regulation of microRNA expression by scaffold/matrix-attachment regions. |
| Volume: |
39 |
| Issue: |
16 |
| Pages: |
6908-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li S |
| Year: |
2015 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Detecting the presence of hippocampus membrane androgen receptors in male SAMP8 mice and their induced synaptic plasticity. |
| Volume: |
414 |
|
| Pages: |
82-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Le Noir S |
| Year: |
2017 |
| Journal: |
Oncotarget |
| Title: |
The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
12929-12940 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu Z |
| Year: |
2009 |
| Journal: |
Neuroscience |
| Title: |
Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation. |
| Volume: |
162 |
| Issue: |
2 |
| Pages: |
396-403 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bossenmeyer-Pourié C |
| Year: |
2019 |
| Journal: |
J Pathol |
| Title: |
N-homocysteinylation of tau and MAP1 is increased in autopsy specimens of Alzheimer's disease and vascular dementia. |
| Volume: |
248 |
| Issue: |
3 |
| Pages: |
291-303 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
992
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
977
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
535
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
699
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
966
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
944
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
692
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
982
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
726
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
666
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
682
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
660
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
977
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
636
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim E |
| Year: |
1997 |
| Journal: |
J Cell Biol |
| Title: |
GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules. |
| Volume: |
136 |
| Issue: |
3 |
| Pages: |
669-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Satoh K |
| Year: |
1997 |
| Journal: |
Genes Cells |
| Title: |
DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95. |
| Volume: |
2 |
| Issue: |
6 |
| Pages: |
415-24 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
154
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
104
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Whoolery CW |
| Year: |
2017 |
| Journal: |
Radiat Res |
| Title: |
Whole-Body Exposure to 28Si-Radiation Dose-Dependently Disrupts Dentate Gyrus Neurogenesis and Proliferation in the Short Term and New Neuron Survival and Contextual Fear Conditioning in the Long Term. |
| Volume: |
188 |
| Issue: |
5 |
| Pages: |
532-551 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
733
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
764
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
795
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
615
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
733
 |
| Fragment?: |
false |
|
•
•
•
•
•
|