Type |
Details |
Score |
Publication |
First Author: |
Banda NK |
Year: |
2011 |
Journal: |
Mol Immunol |
Title: |
Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement. |
Volume: |
49 |
Issue: |
1-2 |
Pages: |
281-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorelik A |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Developmental activities of the complement pathway in migrating neurons. |
Volume: |
8 |
|
Pages: |
15096 |
|
•
•
•
•
•
|
Publication |
First Author: |
Camerer E |
Year: |
2010 |
Journal: |
Dev Cell |
Title: |
Local protease signaling contributes to neural tube closure in the mouse embryo. |
Volume: |
18 |
Issue: |
1 |
Pages: |
25-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Whiley PAF |
Year: |
2020 |
Journal: |
Endocrinology |
Title: |
Activin A Determines Steroid Levels and Composition in the Fetal Testis. |
Volume: |
161 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dasgupta K |
Year: |
2019 |
Journal: |
Dev Biol |
Title: |
Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling. |
Volume: |
455 |
Issue: |
2 |
Pages: |
434-448 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Rooryck C |
Year: |
2011 |
Journal: |
Nat Genet |
Title: |
Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. |
Volume: |
43 |
Issue: |
3 |
Pages: |
197-203 |
|
•
•
•
•
•
|
Allele |
Name: |
MBL associated serine protease 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
MBL associated serine protease 1; endonuclease-mediated mutation 1, Teizo Fujita |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified isoform(s) |
|
•
•
•
•
•
|
Allele |
Name: |
MBL associated serine protease 1; endonuclease-mediated mutation 2, Teizo Fujita |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified isoform(s) |
|
•
•
•
•
•
|
Publication |
First Author: |
Motriuk-Smith D |
Year: |
2005 |
Journal: |
Biomacromolecules |
Title: |
Analysis of the conserved N-terminal domains in major ampullate spider silk proteins. |
Volume: |
6 |
Issue: |
6 |
Pages: |
3152-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rising A |
Year: |
2006 |
Journal: |
Biomacromolecules |
Title: |
N-terminal nonrepetitive domain common to dragline, flagelliform, and cylindriform spider silk proteins. |
Volume: |
7 |
Issue: |
11 |
Pages: |
3120-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao Z |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Structural characterization of minor ampullate spidroin domains and their distinct roles in fibroin solubility and fiber formation. |
Volume: |
8 |
Issue: |
2 |
Pages: |
e56142 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
Spidroin is spider dragline silk. It is composed of two proteins, major ampullate spidroin 1 (MaSp1) and major ampullate spidroin 2 (MaSp2) []. MaSp1 contains five α-helices []. Spidroins contain repetitive units capped between non-repetitive N-terminal and C-terminal domains, whose composition varies among species and thus determines the variety of mechanical properties of spider silks. The C-terminal domains are conserved among spider silk proteins [].This superfamily represents the C-terminal domain of spidroin. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Spidroin is spider dragline silk. It is composed of two proteins, major ampullate spidroin 1 (MaSp1) and major ampullate spidroin 2 (MaSp2) []. MaSp1 contains five α-helices []. Spidroins contain repetitive units capped between non-repetitive N-terminal and C-terminal domains, whose composition varies among species and thus determines the variety of mechanical properties of spider silks. The C-terminal domains are conserved among spider silk proteins [].This is the C-terminal domain of spidroin. |
|
•
•
•
•
•
|
Publication |
First Author: |
Takayama Y |
Year: |
1999 |
Journal: |
Mol Immunol |
Title: |
Gene structure of the P100 serine-protease component of the human Ra-reactive factor. |
Volume: |
36 |
Issue: |
8 |
Pages: |
505-14 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
These proteins belong to MEROPS peptidase family S1 (chymotrypsin family, clan PA(S)), subfamily S1A.This family contains the mammalian mannan-binding lectin-associated serine proteases 1 and 2 (MASP1 and MASP2) and complement components C1s and C1r. The C1 complex, containing C1q, C1s, and C1r, triggers the classical complement pathway. When C1q interacts with antibody, C1r becomes autocatalytically activated. Activated C1r in turn activates C1s, which then cleaves C2 and C4 in the classical pathway.Mannose-binding lectin (MBL) complexes with MASP1, MASP2, and a smaller alternative splice product of the MASP2 gene. Binding of MBL to carbohydrates on the surface of microorganisms triggers activation of the associated MASPs. Then MASP1 activates C3 and C2, whereas MASP2 activates C4 and C2 []. Based on the fact that the gene structures of MASP1, C1r, and C1s are similar except that C1r and C1s lack introns in the region encoding the trypsin domain, it has been proposed that the MASP proteins evolved earlier than C1r and C1s []. The complement pathway is also involved in development [].These sequences typically contain a signal sequence, followed by a CUB domain, an EGF-like domain (which often is not detected), a second CUB domain, two sushi domains (sometimes only one is detected), and a trypsin domain. |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsushita M |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Proteolytic activities of two types of mannose-binding lectin-associated serine protease. |
Volume: |
165 |
Issue: |
5 |
Pages: |
2637-42 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
707
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
706
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
688
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
688
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
704
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
685
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
707
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
694
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
694
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
688
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
694
 |
Fragment?: |
false |
|
•
•
•
•
•
|