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Search results 101 to 135 out of 135 for Masp2

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0.01s
Type Details Score
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: MBL associated serine protease 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: TAR DNA binding protein; targeted mutation 1.1, Janice Robertson
Allele Type: Targeted
Attribute String: Conditional ready
Genotype
Symbol: Tardbp/Tardbp
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * SJL
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Rooryck C
Year: 2011
Journal: Nat Genet
Title: Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome.
Volume: 43
Issue: 3
Pages: 197-203
Publication
First Author: Takayama Y
Year: 1999
Journal: Mol Immunol
Title: Gene structure of the P100 serine-protease component of the human Ra-reactive factor.
Volume: 36
Issue: 8
Pages: 505-14
Protein Domain
Type: Family
Description: These proteins belong to MEROPS peptidase family S1 (chymotrypsin family, clan PA(S)), subfamily S1A.This family contains the mammalian mannan-binding lectin-associated serine proteases 1 and 2 (MASP1 and MASP2) and complement components C1s and C1r. The C1 complex, containing C1q, C1s, and C1r, triggers the classical complement pathway. When C1q interacts with antibody, C1r becomes autocatalytically activated. Activated C1r in turn activates C1s, which then cleaves C2 and C4 in the classical pathway.Mannose-binding lectin (MBL) complexes with MASP1, MASP2, and a smaller alternative splice product of the MASP2 gene. Binding of MBL to carbohydrates on the surface of microorganisms triggers activation of the associated MASPs. Then MASP1 activates C3 and C2, whereas MASP2 activates C4 and C2 []. Based on the fact that the gene structures of MASP1, C1r, and C1s are similar except that C1r and C1s lack introns in the region encoding the trypsin domain, it has been proposed that the MASP proteins evolved earlier than C1r and C1s []. The complement pathway is also involved in development [].These sequences typically contain a signal sequence, followed by a CUB domain, an EGF-like domain (which often is not detected), a second CUB domain, two sushi domains (sometimes only one is detected), and a trypsin domain.
Publication
First Author: Hamilton-Williams EE
Year: 2013
Journal: Mamm Genome
Title: Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity.
Volume: 24
Issue: 9-10
Pages: 358-75
Publication  
First Author: Beaver M
Year: 2024
Journal: Front Immunol
Title: C1q is elevated during chronic Staphylococcus epidermidis central nervous system catheter infection.
Volume: 15
Pages: 1342467
Protein
Organism: Mus musculus/domesticus
Length: 707  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 688  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 688  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 704  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 707  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 694  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 694  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 688  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 694  
Fragment?: false