| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266028 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945128 |
| Age: |
postnatal day 7 |
| Image: |
g00586 P7 |
|
| Specimen Label: |
g00586 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3584908 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3574228 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:3586263 |
| Age: |
postnatal adult |
| Image: |
Adult |
| Note: |
Expression was detected in bipolar cells. |
| Specimen Label: |
Adult |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754028 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945128 |
| Age: |
postnatal day 7 |
| Image: |
g00586 P7 |
|
| Specimen Label: |
g00586 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280923 |
| Pattern: |
Widespread |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945128 |
| Age: |
embryonic day 15.5 |
| Image: |
g00586 E15.5 |
|
| Specimen Label: |
g00586 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945128 |
| Age: |
postnatal day 7 |
| Image: |
g00586 P7 |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g00586 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266523 |
| Pattern: |
Widespread |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945128 |
| Age: |
embryonic day 15.5 |
| Image: |
g00586 E15.5 |
|
| Specimen Label: |
g00586 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4945128 |
| Age: |
embryonic day 15.5 |
| Image: |
g00586 E15.5 |
| Note: |
Expression was region specific and scattered. |
| Specimen Label: |
g00586 E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4885152 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2011-04-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757728 |
| Pattern: |
Widespread |
| Stage: |
TS28 |
| Assay Id: |
MGI:4945128 |
| Age: |
postnatal day 7 |
| Image: |
g00586 P7 |
|
| Specimen Label: |
g00586 P7 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3584908 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717120 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:3586263 |
| Age: |
embryonic day 12.0 |
|
| Note: |
Expression was detected in the outer neuroblastic layer. |
| Specimen Label: |
E12 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3584908 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1717122 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:3586263 |
| Age: |
embryonic day 14.0 |
|
| Note: |
Expression was detected in the outer and inner neuroblastic layers. The expression level was higher in the inner layer. |
| Specimen Label: |
E14 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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UniProt-GOA |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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•
•
•
•
•
|
| Allele |
| Name: |
microtubule associated serine/threonine kinase 2; gene trap A061F01, German Gene Trap Consortium |
| Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant stock, gene trap |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Khan Z |
| Year: |
2019 |
| Journal: |
J Biol Chem |
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Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth. |
| Volume: |
294 |
| Issue: |
37 |
| Pages: |
13755-13768 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang D |
| Year: |
2006 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3. |
| Volume: |
290 |
| Issue: |
2 |
| Pages: |
F428-37 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
MAST (Microtubule-Associated Serine/Threonine) kinases are characterised by containing a serine/threonine kinase domain and a PDZ (postsynaptic density protein-95/discs large/zona occludens-1) domain []. There are four mammalian MAST kinases, named MAST1-MAST4. MAST1, MAST2, and MAST3 bind and phosphorylate the tumor suppressor PTEN, and may contribute to the regulation and stabilization of PTEN []. MAST1 links the dystrophin/utrophin network with microtubule filaments via the syntrophins []. MAST1 localises in the DAPC/UAPC, which is found within the postsynaptic region of the neuromuscular junction (NMJ) and central synapses []. The splice variant of its C-terminal affects its subcellular localisation within neurons []. MAST2 is involved in the regulation of the Fc-gamma receptor of the innate immune response in macrophages, and may also be involved in the regulation of the Na+/H+ exchanger NHE3 []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yano R |
| Year: |
2003 |
| Journal: |
Neuroscience |
| Title: |
Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in the restricted brain regions. |
| Volume: |
117 |
| Issue: |
2 |
| Pages: |
373-81 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
636
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
868
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
658
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1321
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1305
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1570
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2618
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2431
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2426
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1210
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
993
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2444
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2441
 |
| Fragment?: |
false |
|
•
•
•
•
•
|