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Search results 101 to 200 out of 239 for Mdm4

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Type Details Score
GXD Expression      
Probe: MGI:2670381
Assay Type: Northern blot
Annotation Date: 2003-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:2670382
Age: embryonic day 11.5
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2670381
Assay Type: Northern blot
Annotation Date: 2003-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:2670382
Age: embryonic day 10.5
Specimen Label: 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2670381
Assay Type: Northern blot
Annotation Date: 2003-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:2670382
Age: embryonic day 9.5
Specimen Label: 7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2683920
Assay Type: Northern blot
Annotation Date: 2004-01-14
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2683924
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7412967
Assay Type: Western blot
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619826
Stage: TS26
Assay Id: MGI:7412968
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7412967
Assay Type: Western blot
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:7412968
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7412967
Assay Type: Western blot
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7412968
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7412967
Assay Type: Western blot
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7412968
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7412967
Assay Type: Western blot
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7412968
Age: postnatal day 60
Specimen Label: P60
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619823
Stage: TS23
Assay Id: MGI:7413028
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:7413028
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:7413028
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:7413028
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7413028
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7413028
Age: postnatal day 11
Specimen Label: P11
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7413028
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7412935
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7413028
Age: postnatal day 30
Specimen Label: P30
Detected: true
Specimen Num: 8
Publication
First Author: Huang Q
Year: 2020
Journal: EMBO J
Title: MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling.
Volume: 39
Issue: 14
Pages: e104410
Publication
First Author: Shvarts A
Year: 1997
Journal: Genomics
Title: Isolation and identification of the human homolog of a new p53-binding protein, Mdmx.
Volume: 43
Issue: 1
Pages: 34-42
Publication
First Author: He G
Year: 2014
Journal: Mol Cell Biol
Title: AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity.
Volume: 34
Issue: 2
Pages: 148-57
Publication
First Author: Matijasevic Z
Year: 2008
Journal: Mol Cell Biol
Title: MdmX promotes bipolar mitosis to suppress transformation and tumorigenesis in p53-deficient cells and mice.
Volume: 28
Issue: 4
Pages: 1265-73
Publication
First Author: Finch RA
Year: 2002
Journal: Cancer Res
Title: mdmx is a negative regulator of p53 activity in vivo.
Volume: 62
Issue: 11
Pages: 3221-5
Publication
First Author: Marine JC
Year: 2006
Journal: Cell Death Differ
Title: Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.
Volume: 13
Issue: 6
Pages: 927-34
Publication  
First Author: Si S
Year: 2018
Journal: Exp Hematol
Title: Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells.
Volume: 63
Pages: 41-51.e1
Publication
First Author: Huang Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis.
Volume: 115
Issue: 15
Pages: E3368-E3377
Publication
First Author: Kuser-Abali G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: An EZH2-mediated epigenetic mechanism behind p53-dependent tissue sensitivity to DNA damage.
Volume: 115
Issue: 13
Pages: 3452-3457
Publication
First Author: Kon N
Year: 2018
Journal: Oncotarget
Title: Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects.
Volume: 9
Issue: 7
Pages: 7282-7297
Publication
First Author: Yao R
Year: 2001
Journal: Cytogenet Cell Genet
Title: Chromosome mapping and sequence variation of the murine Ras effector gene Nore1.
Volume: 95
Issue: 1-2
Pages: 126-8
Publication
First Author: Marine JC
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Mdmx as an essential regulator of p53 activity.
Volume: 331
Issue: 3
Pages: 750-60
Publication
First Author: Tollini LA
Year: 2014
Journal: Cancer Cell
Title: Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage.
Volume: 26
Issue: 2
Pages: 235-47
Publication
First Author: Terzian T
Year: 2011
Journal: J Pathol
Title: Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.
Volume: 224
Issue: 4
Pages: 540-52
Publication
First Author: Garcia D
Year: 2011
Journal: Genes Dev
Title: Validation of MdmX as a therapeutic target for reactivating p53 in tumors.
Volume: 25
Issue: 16
Pages: 1746-57
Publication  
First Author: Yokoyama M
Year: 2019
Journal: J Mol Cell Cardiol
Title: p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia.
Volume: 129
Pages: 105-117
Publication
First Author: Yokoyama M
Year: 2014
Journal: Cell Rep
Title: Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.
Volume: 7
Issue: 5
Pages: 1691-1703
Publication
First Author: Tian H
Year: 2017
Journal: J Biol Chem
Title: Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
Volume: 292
Issue: 52
Pages: 21614-21622
Publication
First Author: Simeonova I
Year: 2013
Journal: Cell Rep
Title: Mutant mice lacking the p53 C-terminal domain model telomere syndromes.
Volume: 3
Issue: 6
Pages: 2046-58
Publication
First Author: Yang J
Year: 2021
Journal: Cancer Res
Title: MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo.
Volume: 81
Issue: 4
Pages: 898-909
Publication
First Author: Carr MI
Year: 2016
Journal: Cell Rep
Title: Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis.
Volume: 16
Issue: 10
Pages: 2618-2629
Publication
First Author: Wang YV
Year: 2009
Journal: Cancer Cell
Title: Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinases.
Volume: 16
Issue: 1
Pages: 33-43
Publication
First Author: Benosman S
Year: 2007
Journal: Cell Death Differ
Title: Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis.
Volume: 14
Issue: 12
Pages: 2047-57
Publication
First Author: He XY
Year: 2015
Journal: Cell Rep
Title: p53 in the Myeloid Lineage Modulates an Inflammatory Microenvironment Limiting Initiation and Invasion of Intestinal Tumors.
Volume: 13
Issue: 5
Pages: 888-97
Publication
First Author: Huang L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo.
Volume: 108
Issue: 29
Pages: 12001-6
Publication
First Author: Pant V
Year: 2013
Journal: Genes Dev
Title: The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity.
Volume: 27
Issue: 17
Pages: 1857-67
Publication
First Author: Clegg HV
Year: 2012
Journal: PLoS One
Title: Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction.
Volume: 7
Issue: 5
Pages: e38212
Publication
First Author: Zhang Y
Year: 2014
Journal: Dev Biol
Title: Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.
Volume: 396
Issue: 1
Pages: 19-30
Publication
First Author: Kim S
Year: 2014
Journal: Mol Cell
Title: PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.
Volume: 56
Issue: 4
Pages: 564-79
Publication
First Author: Crespo I
Year: 2015
Journal: Am J Pathol
Title: Molecular and Genomic Alterations in Glioblastoma Multiforme.
Volume: 185
Issue: 7
Pages: 1820-33
Publication
First Author: Zhang Y
Year: 2017
Journal: Dev Biol
Title: Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.
Volume: 423
Issue: 1
Pages: 34-45
Publication
First Author: Bowen ME
Year: 2019
Journal: Dev Cell
Title: The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.
Volume: 50
Issue: 2
Pages: 212-228.e6
Publication  
First Author: Alam SS
Year: 2022
Journal: Dis Model Mech
Title: Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis.
Volume: 15
Issue: 6
Publication
First Author: Vuong L
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina.
Volume: 53
Issue: 8
Pages: 4821-31
Publication
First Author: Tiu GC
Year: 2021
Journal: Dev Cell
Title: A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.
Volume: 56
Issue: 14
Pages: 2089-2102.e11
Publication
First Author: Zambrowicz BP
Year: 1998
Journal: Nature
Title: Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.
Volume: 392
Issue: 6676
Pages: 608-11
Publication
First Author: El-Saafin F
Year: 2022
Journal: Cell Death Differ
Title: Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.
Volume: 29
Issue: 5
Pages: 1013-1027
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Rallapalli R
Year: 1999
Journal: J Biol Chem
Title: A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity.
Volume: 274
Issue: 12
Pages: 8299-308