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Search results 101 to 198 out of 198 for Mettl16

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Hits by Category

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_03
Specimen Label: euxassay_000834_03
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_04
Specimen Label: euxassay_000834_04
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_05
Specimen Label: euxassay_000834_05
Detected: true
Specimen Num: 5
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_06
Specimen Label: euxassay_000834_06
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_07
Specimen Label: euxassay_000834_07
Detected: true
Specimen Num: 7
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_08
Specimen Label: euxassay_000834_08
Detected: true
Specimen Num: 8
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_09
Specimen Label: euxassay_000834_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_12
Specimen Label: euxassay_000834_12
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_13
Specimen Label: euxassay_000834_13
Detected: true
Specimen Num: 12
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_14
Specimen Label: euxassay_000834_14
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_15
Specimen Label: euxassay_000834_15
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_16
Specimen Label: euxassay_000834_16
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_17
Specimen Label: euxassay_000834_17
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_18
Specimen Label: euxassay_000834_18
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_19
Specimen Label: euxassay_000834_19
Detected: true
Specimen Num: 18
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_1804238
Specimen Label: JAX_1804238
Detected: true
Specimen Num: 11
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737201
Specimen Label: JAX_737201
Detected: true
Specimen Num: 42
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1776323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_05
Specimen Label: euxassay_000834_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1776323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_06
Specimen Label: euxassay_000834_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1776323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_17
Specimen Label: euxassay_000834_17
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:1029601
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1776323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826169
Age: embryonic day 14.5
Image: euxassay_000834_18
Specimen Label: euxassay_000834_18
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_1804241
Specimen Label: JAX_1804241
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737195
Specimen Label: JAX_737195
Detected: true
Specimen Num: 39
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_1804236
Specimen Label: JAX_1804236
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737159
Specimen Label: JAX_737159
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3599828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737193
Specimen Label: JAX_737193
Detected: true
Specimen Num: 38
•
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737163
Specimen Label: JAX_737163
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_1804242
Specimen Label: JAX_1804242
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737203
Specimen Label: JAX_737203
Detected: true
Specimen Num: 43
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737165
Specimen Label: JAX_737165
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737185
Specimen Label: JAX_737185
Detected: true
Specimen Num: 34
•
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_1804240
Specimen Label: JAX_1804240
Detected: true
Specimen Num: 13
•
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737207
Specimen Label: JAX_737207
Detected: true
Specimen Num: 45
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•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_1804244
Specimen Label: JAX_1804244
Detected: true
Specimen Num: 17
•
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•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691751
Age: postnatal adult
Image: JAX_737167
Specimen Label: JAX_737167
Detected: true
Specimen Num: 25
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Protein
Q9CQG2-2
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Publication
22357600 | J:181631
First Author: Gehman LT
Year: 2012
Journal: Genes Dev
Title: The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.
Volume: 26
Issue: 5
Pages: 445-60
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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•
Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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•
•
•
Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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•
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q5SW13
Organism: Mus musculus/domesticus
Length: 33  
Fragment?: true
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UniProt Feature
UniProt Feature
Begin: 1
Description: RNA N6-adenosine-methyltransferase METTL16
Type: chain
End: 553
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Allele
Mettl16<em3Rspi> | MGI:7514380
 
Name: methyltransferase 16, N6-methyladenosine; endonuclease-mediated mutation 3, Ramesh S Pillai
Allele Type: Endonuclease-mediated
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Allele
Mettl16<em4Rspi> | MGI:7514381
 
Name: methyltransferase 16, N6-methyladenosine; endonuclease-mediated mutation 4, Ramesh S Pillai
Allele Type: Endonuclease-mediated
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HT Experiment
GSE116329 | Methylation of structured RNA by the m6A writer METTL16 is essential for mouse embryonic development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
F8WHZ7
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Publication
28525753 | -
First Author: Pendleton KE
Year: 2017
Journal: Cell
Title: The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.
Volume: 169
Issue: 5
Pages: 824-835.e14
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Allele
Mettl16<em2Smoc> | MGI:7291044
Name: methyltransferase 16, N6-methyladenosine; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Mettl16<em1Smoc> | MGI:7291043
Name: methyltransferase 16, N6-methyladenosine; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6355016 | C57BL/6JSmoc-Mettl16<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7623431 | C57BL/6JSmoc-Mettl16<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
18021804 | -
First Author: Sergiev PV
Year: 2008
Journal: J Mol Biol
Title: The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.
Volume: 375
Issue: 1
Pages: 291-300
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Publication
27872311 | -
First Author: Brown JA
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Methyltransferase-like protein 16 binds the 3'-terminal triple helix of MALAT1 long noncoding RNA.
Volume: 113
Issue: 49
Pages: 14013-14018
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Protein Domain
IPR010286 | METTL16/RlmF
Type: Family
Description: This family includes ribosomal RNA large subunit methyltransferase F (RlmF), and related proteins, including methyltransferase-like protein 16 (METTL16). METTL16 is a conserved RNA methyltransferase which interacts specifically with the MALAT1 triple helix. METTL16 shows nuclear localisation []. Another functional study indicates that METTL16 regulates expression of human MAT2A, which encodes the SAM synthetase expressed in most cells. Furthermore, results indicate that METTL16 is the long-unknown methyltransferase for the U6 spliceosomal small nuclear RNA (snRNA) and it has evolved an additional function in vertebrates to control SAM homeostasis by post-transcriptionally regulating SAM synthetase gene expression [].RlmF methylates the adenine in position 1618 of 23S rRNA []. This family also includes psilocybin synthase (PsiM), which is a methyltransferase involved in the biosynthesis of the psychotropic agent psilocybin from the mushroom Psilocybe cubensis [].
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Protein Domain
IPR017182 | METTL16/PsiM
Type: Family
Description: METTL16 is an U6 snRNA methyltransferase that methylates adenosine residues of a subset of RNAs. It plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts [].This entry also includes PsiM from Psilocybe cubensis. PsiM is part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product. It serves as a methyltransferase that catalyze iterative N-methyl transfer as the terminal biosynthetic step [].
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Publication
28763571 | -
First Author: Fricke J
Year: 2017
Journal: Angew Chem Int Ed Engl
Title: Enzymatic Synthesis of Psilocybin.
Volume: 56
Issue: 40
Pages: 12352-12355
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Protein
Q5SW15
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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