Type |
Details |
Score |
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
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•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
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•
•
•
•
•
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Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
•
•
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•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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•
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Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
•
•
•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
•
•
•
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Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
•
•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
•
•
•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
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•
|
Allele |
Name: |
O-6-methylguanine-DNA methyltransferase; targeted mutation 1, Leona D Samson |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Becker K |
Year: |
2003 |
Journal: |
Carcinogenesis |
Title: |
DNA repair protein MGMT protects against N-methyl-N-nitrosourea-induced conversion of benign into malignant tumors. |
Volume: |
24 |
Issue: |
3 |
Pages: |
541-6 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
211
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Winter JM |
Year: |
2014 |
Journal: |
J Nutrigenet Nutrigenomics |
Title: |
Role of Red Meat and Resistant Starch in Promutagenic Adduct Formation, MGMT Repair, Thymic Lymphoma and Intestinal Tumourigenesis in Msh2 -Deficient Mice. |
Volume: |
7 |
Issue: |
4-6 |
Pages: |
299-313 |
|
•
•
•
•
•
|
Allele |
Name: |
O-6-methylguanine-DNA methyltransferase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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•
•
•
•
•
|
Publication |
First Author: |
Becker K |
Year: |
1996 |
Journal: |
Cancer Res |
Title: |
Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis. |
Volume: |
56 |
Issue: |
14 |
Pages: |
3244-9 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 3, Klaus Becker |
Allele Type: |
Transgenic |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, transgenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(MGMT)3Bec/Tg(MGMT)3Bec |
Background: |
involves: NMRI |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin X |
Year: |
2000 |
Journal: |
Jpn J Cancer Res |
Title: |
Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O(6)-methylguanine-DNA methyltransferase. |
Volume: |
91 |
Issue: |
11 |
Pages: |
1085-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mukai T |
Year: |
2002 |
Journal: |
Oncogene |
Title: |
Gene silencing in phenomena related to DNA repair. |
Volume: |
21 |
Issue: |
58 |
Pages: |
9033-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blough MD |
Year: |
2007 |
Journal: |
Cancer Res |
Title: |
O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells. |
Volume: |
67 |
Issue: |
2 |
Pages: |
580-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vengoji R |
Year: |
2021 |
Journal: |
J Exp Clin Cancer Res |
Title: |
Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for Glioblastoma. |
Volume: |
40 |
Issue: |
1 |
Pages: |
335 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shirakami Y |
Year: |
2012 |
Journal: |
Carcinogenesis |
Title: |
Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration. |
Volume: |
33 |
Issue: |
2 |
Pages: |
268-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen T |
Year: |
1998 |
Journal: |
Teratog Carcinog Mutagen |
Title: |
Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models. |
Volume: |
18 |
Issue: |
3 |
Pages: |
101-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allay E |
Year: |
1999 |
Journal: |
Oncogene |
Title: |
Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea. |
Volume: |
18 |
Issue: |
25 |
Pages: |
3783-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakatsuru Y |
Year: |
1993 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis. |
Volume: |
90 |
Issue: |
14 |
Pages: |
6468-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borgenvik A |
Year: |
2022 |
Journal: |
Cancer Res |
Title: |
Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma. |
Volume: |
82 |
Issue: |
24 |
Pages: |
4586-4603 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao S |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance. |
Volume: |
14 |
Issue: |
10 |
Pages: |
e0222392 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anisimov VN |
Year: |
2001 |
Journal: |
Mech Ageing Dev |
Title: |
Mutant and genetically modified mice as models for studying the relationship between aging and carcinogenesis. |
Volume: |
122 |
Issue: |
12 |
Pages: |
1221-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reese JS |
Year: |
2001 |
Journal: |
Oncogene |
Title: |
Overexpression of human O6-alkylguanine DNA alkyltransferase (AGT) prevents MNU induced lymphomas in heterozygous p53 deficient mice. |
Volume: |
20 |
Issue: |
38 |
Pages: |
5258-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walter CA |
Year: |
2001 |
Journal: |
Ann N Y Acad Sci |
Title: |
Health span and life span in transgenic mice with modulated DNA repair. |
Volume: |
928 |
|
Pages: |
132-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walter CA |
Year: |
1997 |
Journal: |
Mech Ageing Dev |
Title: |
Analysis and modulation of DNA repair in aging. |
Volume: |
98 |
Issue: |
3 |
Pages: |
203-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Povey AC |
Year: |
2002 |
Journal: |
J Nutr |
Title: |
DNA alkylation and repair in the large bowel: animal and human studies. |
Volume: |
132 |
Issue: |
11 Suppl |
Pages: |
3518S-3521S |
|
•
•
•
•
•
|
Publication |
First Author: |
Allay E |
Year: |
1997 |
Journal: |
Oncogene |
Title: |
Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase. |
Volume: |
15 |
Issue: |
17 |
Pages: |
2127-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang XY |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Achaete-scute complex homolog-1 promotes DNA repair in the lung carcinogenesis through matrix metalloproteinase-7 and O(6)-methylguanine-DNA methyltransferase. |
Volume: |
7 |
Issue: |
12 |
Pages: |
e52832 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fahrer J |
Year: |
2013 |
Journal: |
Carcinogenesis |
Title: |
O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer. |
Volume: |
34 |
Issue: |
11 |
Pages: |
2435-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin X |
Year: |
1999 |
Journal: |
Oncogene |
Title: |
Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT. |
Volume: |
18 |
Issue: |
30 |
Pages: |
4394-400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishikawa T |
Year: |
2004 |
Journal: |
Cancer Sci |
Title: |
DNA repair and cancer: lessons from mutant mouse models. |
Volume: |
95 |
Issue: |
2 |
Pages: |
112-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jackson PE |
Year: |
2003 |
Journal: |
Carcinogenesis |
Title: |
Associations between tissue-specific DNA alkylation, DNA repair and cell proliferation in the colon and colon tumour yield in mice treated with 1,2-dimethylhydrazine. |
Volume: |
24 |
Issue: |
3 |
Pages: |
527-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu L |
Year: |
1999 |
Journal: |
Carcinogenesis |
Title: |
Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell. |
Volume: |
20 |
Issue: |
2 |
Pages: |
279-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christmann M |
Year: |
2012 |
Journal: |
Mutat Res |
Title: |
O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke. |
Volume: |
736 |
Issue: |
1-2 |
Pages: |
64-74 |
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•
•
•
•
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