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Search results 101 to 129 out of 129 for Mpp1

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0.019s
Type Details Score
HT Sample
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 8-12
Stage: 28
Structure . Name: bone marrow
Notes: MPP1 (LSK CD34+ CD135- CD150+ CD48-)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 8-12
Stage: 28
Structure . Name: bone marrow
Notes: MPP1 (LSK CD34+ CD135- CD150+ CD48-)
Curation Status: Curated
Allele
Name: membrane protein, palmitoylated; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Protein
Organism: Mus musculus/domesticus
Length: 394  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1774  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1734  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1348  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1762  
Fragment?: false
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Publication
First Author: Li L
Year: 2022
Journal: Neuron
Title: Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes.
Volume: 110
Issue: 16
Pages: 2646-2663.e6
Publication
First Author: Little JN
Year: 2019
Journal: Hum Mol Genet
Title: p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects.
Volume: 28
Issue: 3
Pages: 434-447
Publication
First Author: Du W
Year: 2013
Journal: J Immunol
Title: Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.
Volume: 191
Issue: 5
Pages: 2806-17
Publication
First Author: Kamijo A
Year: 2016
Journal: Histochem Cell Biol
Title: Immunohistochemical study of the membrane skeletal protein, membrane protein palmitoylated 6 (MPP6), in the mouse small intestine.
Volume: 145
Issue: 1
Pages: 81-92
Publication
First Author: Westendorf JM
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope.
Volume: 91
Issue: 2
Pages: 714-8
Publication  
First Author: Alla JA
Year: 2023
Journal: Biochem Pharmacol
Title: Identification of membrane palmitoylated protein 1 (MPP1) as a heart-failure-promoting protein triggered by cardiovascular risk factors and aging.
Volume: 217
Pages: 115789
Publication
First Author: Nunomura W
Year: 2000
Journal: J Biol Chem
Title: Regulation of protein 4.1R, p55, and glycophorin C ternary complex in human erythrocyte membrane.
Volume: 275
Issue: 32
Pages: 24540-6
Publication
First Author: Marfatia SM
Year: 1997
Journal: J Biol Chem
Title: The PDZ domain of human erythrocyte p55 mediates its binding to the cytoplasmic carboxyl terminus of glycophorin C. Analysis of the binding interface by in vitro mutagenesis.
Volume: 272
Issue: 39
Pages: 24191-7
Protein Domain
Type: Domain
Description: This entry represents the SH3 domain of MPP1, which is a ubiquitously-expressed scaffolding protein that plays roles in regulating neutrophil polarity, cell shape, hair cell development, and neural development and patterning of the retina [, ]. It was originally identified as an erythrocyte protein that stabilizes the actin cytoskeleton to the plasma membrane by forming a complex with 4.1R protein and glycophorin C [, ]. MPP1 belongs to the membrane-associated guanylate kinase (MAGUK) p55 subfamily.The membrane-associated guanylate kinase (MAGUK) p55 subfamily (also known as MPP subfamily) members include the Drosophila Stardust protein and its vertebrate homologues, MPP1-7. They contain the core of three domains characteristic of MAGUK (membrane-associated guanylate kinase) proteins: PDZ, SH3, and guanylate kinase (GuK). In addition, they also contain the Hook (Protein 4.1 Binding) motif in between the SH3 and GuK domains []. MPP2-7 have two additional L27 domains at their N terminus. The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain [].
Publication
First Author: McNeely KC
Year: 2017
Journal: Neural Dev
Title: Mutation of Kinesin-6 Kif20b causes defects in cortical neuron polarization and morphogenesis.
Volume: 12
Issue: 1
Pages: 5
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
Publication
First Author: Stöhr H
Year: 2001
Journal: Genomics
Title: Cloning and characterization of the human retina-specific gene MPP4, a novel member of the p55 subfamily of MAGUK proteins.
Volume: 74
Issue: 3
Pages: 377-84
Protein
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
Publication  
First Author: te Velthuis AJ
Year: 2007
Journal: BMC Evol Biol
Title: Molecular evolution of the MAGUK family in metazoan genomes.
Volume: 7
Pages: 129
Protein
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 427  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 466  
Fragment?: false