Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3511440 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-12-20 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3511467 |
Age: |
postnatal week 8 |
|
|
Specimen Label: |
Kidney |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3511440 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-12-20 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3511467 |
Age: |
postnatal week 8 |
|
|
Specimen Label: |
Ovary |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3511440 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-12-20 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3511467 |
Age: |
postnatal week 8 |
|
|
Specimen Label: |
Testis |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-14 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5305829 |
Age: |
postnatal |
|
|
Specimen Label: |
Hsf1-/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-14 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5305829 |
Age: |
postnatal |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-14 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570525 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5305837 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
Hsf1+/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-14 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570525 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5305837 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
Hsf1-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797225 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5306027 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
Hsf1+/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797225 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5306027 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
Hsf1-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570525 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5306265 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
+/+;Hsf1-/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-24 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5306993 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Hsf1+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305802 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-02-24 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5306993 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Hsf1-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305843 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-02-15 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3570525 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5306037 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
5B +/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5305843 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-02-15 |
Strength: |
Weak |
Sex: |
Female |
Emaps: |
EMAPS:3570525 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5306037 |
Age: |
embryonic day 17.5 |
|
Note: |
The number of expression foci is reduced. |
Specimen Label: |
5B -/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Her C |
Year: |
2001 |
Journal: |
Mamm Genome |
Title: |
Mouse MutS homolog 4 is predominantly expressed in testis and interacts with MutS homolog 5. |
Volume: |
12 |
Issue: |
1 |
Pages: |
73-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiao H |
Year: |
2018 |
Journal: |
Mol Cell |
Title: |
Impeding DNA Break Repair Enables Oocyte Quality Control. |
Volume: |
72 |
Issue: |
2 |
Pages: |
211-221.e3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kolas NK |
Year: |
2004 |
Journal: |
Cytogenet Genome Res |
Title: |
Novel and diverse functions of the DNA mismatch repair family in mammalian meiosis and recombination. |
Volume: |
107 |
Issue: |
3-4 |
Pages: |
216-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamer G |
Year: |
2006 |
Journal: |
J Cell Sci |
Title: |
Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex. |
Volume: |
119 |
Issue: |
Pt 19 |
Pages: |
4025-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lyndaker AM |
Year: |
2013 |
Journal: |
PLoS Genet |
Title: |
Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance. |
Volume: |
9 |
Issue: |
2 |
Pages: |
e1003320 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reynolds A |
Year: |
2013 |
Journal: |
Nat Genet |
Title: |
RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis. |
Volume: |
45 |
Issue: |
3 |
Pages: |
269-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kolas NK |
Year: |
2005 |
Journal: |
J Cell Biol |
Title: |
Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I. |
Volume: |
171 |
Issue: |
3 |
Pages: |
447-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang F |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
Meiotic failure in male mice lacking an X-linked factor. |
Volume: |
22 |
Issue: |
5 |
Pages: |
682-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. |
Volume: |
10 |
Issue: |
1 |
Pages: |
564 |
|
•
•
•
•
•
|
Publication |
First Author: |
Holloway JK |
Year: |
2011 |
Journal: |
PLoS Genet |
Title: |
Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis. |
Volume: |
7 |
Issue: |
6 |
Pages: |
e1002094 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanno N |
Year: |
2022 |
Journal: |
iScience |
Title: |
FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis. |
Volume: |
25 |
Issue: |
4 |
Pages: |
104008 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang T |
Year: |
2023 |
Journal: |
Nucleic Acids Res |
Title: |
SPIDR is required for homologous recombination during mammalian meiosis. |
Volume: |
51 |
Issue: |
8 |
Pages: |
3855-3868 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2023 |
Journal: |
EMBO Rep |
Title: |
M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination. |
Volume: |
24 |
Issue: |
2 |
Pages: |
e55778 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ito M |
Year: |
2025 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. |
Volume: |
122 |
Issue: |
2 |
Pages: |
e2412961121 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2018 |
Journal: |
Commun Biol |
Title: |
Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis. |
Volume: |
1 |
|
Pages: |
147 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daniel K |
Year: |
2011 |
Journal: |
Nat Cell Biol |
Title: |
Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. |
Volume: |
13 |
Issue: |
5 |
Pages: |
599-610 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kouznetsova A |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Meiosis in mice without a synaptonemal complex. |
Volume: |
6 |
Issue: |
12 |
Pages: |
e28255 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le Masson F |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis. |
Volume: |
31 |
Issue: |
16 |
Pages: |
3410-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Santucci-Darmanin S |
Year: |
2002 |
Journal: |
Hum Mol Genet |
Title: |
The DNA mismatch-repair MLH3 protein interacts with MSH4 in meiotic cells, supporting a role for this MutL homolog in mammalian meiotic recombination. |
Volume: |
11 |
Issue: |
15 |
Pages: |
1697-706 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu H |
Year: |
2019 |
Journal: |
Nucleic Acids Res |
Title: |
SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice. |
Volume: |
47 |
Issue: |
11 |
Pages: |
5670-5683 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2019 |
Journal: |
Sci Adv |
Title: |
SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. |
Volume: |
5 |
Issue: |
1 |
Pages: |
eaau9780 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
186
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
175
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
177
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
138
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
184
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the Protein SPO16 homologue (SPO16, also known as Synaptonemal complex reinforcing element SCRE), including the mammalian orthologue of budding yeast Spo16. It plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC), resulting in the SC stabilization which ensures the progression of meiotic prophase I in male and female germ cells [. It promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 []. It is also required for the localization of TEX11 and MSH4 to recombination intermediates []. |
|
•
•
•
•
•
|
Publication |
First Author: |
McNairn AJ |
Year: |
2017 |
Journal: |
Genetics |
Title: |
Repair of Meiotic DNA Breaks and Homolog Pairing in Mouse Meiosis Requires a Minichromosome Maintenance (MCM) Paralog. |
Volume: |
205 |
Issue: |
2 |
Pages: |
529-537 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Vries FA |
Year: |
2005 |
Journal: |
Genes Dev |
Title: |
Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation. |
Volume: |
19 |
Issue: |
11 |
Pages: |
1376-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lipkin SM |
Year: |
2002 |
Journal: |
Nat Genet |
Title: |
Meiotic arrest and aneuploidy in MLH3-deficient mice. |
Volume: |
31 |
Issue: |
4 |
Pages: |
385-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moens PB |
Year: |
2007 |
Journal: |
J Cell Sci |
Title: |
Initiation and resolution of interhomolog connections: crossover and non-crossover sites along mouse synaptonemal complexes. |
Volume: |
120 |
Issue: |
Pt 6 |
Pages: |
1017-27 |
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