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Search results 101 to 144 out of 144 for Msrb1

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0.018s
Type Details Score
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Allele
Name: methionine sulfoxide reductase B2; endonuclease-mediated mutation 1, Robert Levine
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: mutant stock, targeted mutation, endonuclease-mediated mutation
Publication
First Author: Kim HY
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase.
Volume: 320
Issue: 4
Pages: 1277-83
Publication
First Author: Gladyshev VN
Year: 2016
Journal: J Biol Chem
Title: Selenoprotein Gene Nomenclature.
Volume: 291
Issue: 46
Pages: 24036-24040
Publication
First Author: Tarrago L
Year: 2010
Journal: J Biol Chem
Title: Plant thioredoxin CDSP32 regenerates 1-cys methionine sulfoxide reductase B activity through the direct reduction of sulfenic acid.
Volume: 285
Issue: 20
Pages: 14964-72
Publication
First Author: Pérez-Ruiz JM
Year: 2006
Journal: Plant Cell
Title: Rice NTRC is a high-efficiency redox system for chloroplast protection against oxidative damage.
Volume: 18
Issue: 9
Pages: 2356-68
Protein Domain
Type: Family
Description: Thioredoxins (Trxs) are ubiquitous enzymes with a CXXC active site that catalyses the reduction of disulfide bonds. This entry represents a group of plant thioredoxin-like proteins, including AtCDSP32 from Arabidopsis and OsCDSP32 from rice. AtCDSP32 includes two Trx modules with one potential active site (219)CGPC(222) and three extra Cys, this region is responsible for the insulin reduction activity of the protein []. It forms a heterodimeric complex with MSRB1 (methionine sulfoxide reductases B 1) via reduction of the sulfenic acid formed on MSRB1 catalytic Cys after methionine sulfoxide reduction [].Thioredoxins [, , , ]are small disulphide-containing redox proteins that have been found in all the kingdoms of living organisms. Thioredoxin serves as a general protein disulphide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of two cysteine thiol groups to a disulphide, accompanied by the transfer of two electrons and two protons. The net result is the covalent interconversion of a disulphide and a dithiol. In the NADPH-dependent protein disulphide reduction, thioredoxin reductase (TR) catalyses the reduction of oxidised thioredoxin (trx) by NADPH using FAD and its redox-active disulphide; reduced thioredoxin then directly reduces the disulphide in the substrate protein [].Thioredoxin is present in prokaryotes and eukaryotes and the sequence around the redox-active disulphide bond is well conserved. All thioredoxins contain a cis-proline located in a loop preceding β-strand 4, which makes contact with the active site cysteines, and is important for stability and function []. Thioredoxin belongs to astructural family that includes glutaredoxin, glutathione peroxidase, bacterial protein disulphide isomerase DsbA, and the N-terminal domain of glutathione transferase []. Thioredoxins have a beta-alpha unit preceding the motif common to all these proteins.A number of eukaryotic proteins contain domains evolutionary related to thioredoxin, most of them are protein disulphide isomerases (PDI). PDI () [, , ]is an endoplasmic reticulum multi-functional enzyme that catalyses the formation and rearrangement of disulphide bonds during protein folding []. All PDI contains two or three (ERp72) copies of the thioredoxin domain, each of which contributes to disulphide isomerase activity, but which are functionally non-equivalent []. Moreover, PDI exhibits chaperone-like activity towards proteins that contain no disulphide bonds, i.e. behaving independently of its disulphide isomerase activity []. The various forms of PDI which are currently known are:PDI major isozyme; a multifunctional protein that also function as the beta subunit of prolyl 4-hydroxylase (), as a component of oligosaccharyl transferase (), as thyroxine deiodinase (), as glutathione-insulin transhydrogenase () and as a thyroid hormone-binding proteinERp60 (ER-60; 58 Kd microsomal protein). ERp60 was originally thought to be a phosphoinositide-specific phospholipase C isozyme and later to be a protease.ERp72.ERp5.Bacterial proteins that act as thiol:disulphide interchange proteins that allows disulphide bond formation in some periplasmic proteins also contain a thioredoxin domain. These proteins include:Escherichia coli DsbA (or PrfA) and its orthologs in Vibrio cholerae (TtcpG) and Haemophilus influenzae (Por).E. coli DsbC (or XpRA) and its orthologues in Erwinia chrysanthemi and H. influenzae.E. coli DsbD (or DipZ) and its H. influenzae orthologue.E. coli DsbE (or CcmG) and orthologues in H. influenzae.Rhodobacter capsulatus (Rhodopseudomonas capsulata) (HelX), Rhiziobiacae (CycY and TlpA).
Publication  
First Author: Holmgren A
Year: 1985
Journal: Annu Rev Biochem
Title: Thioredoxin.
Volume: 54
Pages: 237-71
Publication
First Author: Freedman RB
Year: 1988
Journal: Biochem Soc Trans
Title: Protein disulphide-isomerase: a homologue of thioredoxin implicated in the biosynthesis of secretory proteins.
Volume: 16
Issue: 2
Pages: 96-9
Publication
First Author: Song JL
Year: 1995
Journal: Eur J Biochem
Title: Chaperone-like activity of protein disulfide-isomerase in the refolding of rhodanese.
Volume: 231
Issue: 2
Pages: 312-6
Publication
First Author: Kivirikko KI
Year: 1989
Journal: FASEB J
Title: Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit.
Volume: 3
Issue: 5
Pages: 1609-17
Publication
First Author: Puig A
Year: 1994
Journal: J Biol Chem
Title: The role of the thiol/disulfide centers and peptide binding site in the chaperone and anti-chaperone activities of protein disulfide isomerase.
Volume: 269
Issue: 29
Pages: 19128-35
Publication
First Author: Lyles MM
Year: 1994
Journal: J Biol Chem
Title: Mutations in the thioredoxin sites of protein disulfide isomerase reveal functional nonequivalence of the N- and C-terminal domains.
Volume: 269
Issue: 49
Pages: 30946-52
Publication
First Author: Saarinen M
Year: 1995
Journal: Structure
Title: Crystal structure of thioredoxin-2 from Anabaena.
Volume: 3
Issue: 10
Pages: 1097-108
Publication
First Author: Holmgren A
Year: 1995
Journal: Structure
Title: Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfide.
Volume: 3
Issue: 3
Pages: 239-43
Publication
First Author: Martin JL
Year: 1995
Journal: Structure
Title: Thioredoxin--a fold for all reasons.
Volume: 3
Issue: 3
Pages: 245-50
Publication
First Author: Freedman RB
Year: 1994
Journal: Trends Biochem Sci
Title: Protein disulphide isomerase: building bridges in protein folding.
Volume: 19
Issue: 8
Pages: 331-6
Publication
First Author: Holmgren A
Year: 1989
Journal: J Biol Chem
Title: Thioredoxin and glutaredoxin systems.
Volume: 264
Issue: 24
Pages: 13963-6