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Search results 101 to 162 out of 162 for Nab2

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Type Details Score
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
34139237 | J:339892
First Author: Corgiat EB
Year: 2021
Journal: J Biol Chem
Title: The RNA-binding protein Nab2 regulates the proteome of the developing Drosophila brain.
Volume: 297
Issue: 1
Pages: 100877
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Publication
36849419 | J:355314
First Author: Choi EY
Year: 2023
Journal: J Neurosci
Title: Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3.
Volume: 43
Issue: 13
Pages: 2242-2259
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Interaction Experiment
Srinivasan R (2006)
Description: NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.
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Publication
15208322 | -
First Author: Suntharalingam M
Year: 2004
Journal: J Biol Chem
Title: Nuclear export of the yeast mRNA-binding protein Nab2 is linked to a direct interaction with Gfd1 and to Gle1 function.
Volume: 279
Issue: 34
Pages: 35384-91
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Publication
16574654 | -
First Author: Srinivasan R
Year: 2006
Journal: J Biol Chem
Title: NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.
Volume: 281
Issue: 22
Pages: 15129-37
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Protein Domain
IPR021083 | Nab2_N
Type: Domain
Description: Nab2 is a yeast heterogeneous nuclear ribonucleoprotein that modulates poly(A) tail length and mRNA. This is the N-terminal domain of the protein which mediates interactions with the C-terminal globular domain, Myosin-like protein 1 and the mRNA export factor, Gfd1 []. The N-terminal domain of Nab2 shows a structure of a helical fold. The N-terminal domain of Nab2 is thought to mediate protein:protein interactions that facilitate the nuclear export of mRNA []. An essential hydrophobic Phe73 patch on the N-terminal domain is thought to be an important component of the interface between Nab2 and Mlp1 [].
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Protein Domain
IPR006986 | Nab1_C
Type: Domain
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This C-terminal region is found only in the Nab1 subfamily.
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Publication
18190927 | -
First Author: Grant RP
Year: 2008
Journal: J Mol Biol
Title: Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2.
Volume: 376
Issue: 4
Pages: 1048-59
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Protein
Q9CU49
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
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Protein Domain
IPR006988 | Nab_N
Type: Domain
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This entry represents the N-terminal NAB domain, which interacts with the EGR1 inhibitory domain (R1) []. It may also mediate multimerisation.
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Protein
Q61122
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: false
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Protein
A0A087WSU4
Organism: Mus musculus/domesticus
Length: 485  
Fragment?: false
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Protein
E9PZ64
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
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Publication
9418898 | -
First Author: Swirnoff AH
Year: 1998
Journal: Mol Cell Biol
Title: Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain.
Volume: 18
Issue: 1
Pages: 512-24
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Protein
D3Z008
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: true
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Publication
10734128 | -
First Author: Sevetson BR
Year: 2000
Journal: J Biol Chem
Title: A novel activation function for NAB proteins in EGR-dependent transcription of the luteinizing hormone beta gene.
Volume: 275
Issue: 13
Pages: 9749-57
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Publication
24671764 | -
First Author: Kelly SM
Year: 2014
Journal: RNA
Title: A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length.
Volume: 20
Issue: 5
Pages: 681-8
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Protein
A0A1Y7VK72
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: true
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Protein
Q8BSC5
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Protein
A0A1Y7VJD9
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Publication
17428824 | -
First Author: Terriente Félix J
Year: 2007
Journal: Development
Title: Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development.
Volume: 134
Issue: 10
Pages: 1845-52
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Publication
8474438 | -
First Author: Anderson JT
Year: 1993
Journal: Mol Cell Biol
Title: NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability.
Volume: 13
Issue: 5
Pages: 2730-41
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Publication
11779864 | -
First Author: Green DM
Year: 2002
Journal: J Biol Chem
Title: Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p.
Volume: 277
Issue: 10
Pages: 7752-60
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Publication
11927564 | -
First Author: Hector RE
Year: 2002
Journal: EMBO J
Title: Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export.
Volume: 21
Issue: 7
Pages: 1800-10
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Protein Domain
IPR006989 | NAB_co-repressor_dom
Type: Domain
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This entry represents a NAB domain 2 of the protein. It is necessary for transcriptional repression by the Nab proteins []. It is also required for transcription activation by Nab proteins at Nab-activated promoters [].
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Protein Domain
IPR038398 | NCD2_sf
Type: Homologous_superfamily
Description: Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. This entry represents a NAB domain 2 of the protein. It is necessary for transcriptional repression by the Nab proteins []. It is also required for transcription activation by Nab proteins at Nab-activated promoters [].
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Protein Domain
IPR039040 | NAB_fam
Type: Family
Description: Proteins in this family are transcriptional regulators, including Nab (NGFI-A-binding protein) from Drosophila and Nab1/2 from mammals. Nab1 and Nab2 are co-repressors that specifically interact with and repress transcription mediated by the three members of the NGFI-A (Egr-1, Krox24, zif/268) family of eukaryotic (metazoa) transcription factors []. Drosophila Nab controls the activity of zinc-finger transcription factors, such as Squeeze and Rotund, in Drosophila development [].
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Protein Domain
IPR040366 | Nab2/ZC3H14
Type: Family
Description: Budding yeast Nab2 is a nuclear polyadenylated RNA-binding protein that contains seven CCCH-type zinc fingers and an RGG box []. It is required for nuclear mRNA export and poly(A) tail length control [, ]. The tertiary structure has been solved and the protein is all helical (). Its animal homologue, known as ZC3H14, has been shown to control poly(A) tail length in neuronal cells [].
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Protein Domain
IPR043094 | Nab2/ZC3H14_N_sf
Type: Homologous_superfamily
Description: This superfamily represents the N-terminal domain of the nuclear abundant poly(A) RNA-bind protein 2 (Nab2), a yeast heterogeneous nuclear ribonucleoprotein that modulates poly(A) tail length and mRNA. This domain can also be found in Its animal homologue, ZC3H14, which has been shown to control poly(A) tail length in neuronal cells []. The N-terminal domain mediates interactions with the C-terminal globular domain, Myosin-like protein 1 and the mRNA export factor, Gfd1. An essential hydrophobic Phe73 patch on the N-terminal domain is thought to be an important component of the interface between Nab2 and Mlp1 [].
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Publication
39461343 | J:359786
First Author: Li Q
Year: 2024
Journal: Mol Cell
Title: ZC3H14 facilitates backsplicing by binding to exon-intron boundary and 3' UTR.
Volume: 84
Issue: 22
Pages: 4314-4333.e9
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Protein
Q61127
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Protein
Q3U247
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
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Protein
Q3TYF1
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q3TBL2
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
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Publication
19706684 | J:153081
First Author: Mayer SI
Year: 2009
Journal: J Cell Sci
Title: Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors.
Volume: 122
Issue: Pt 18
Pages: 3340-50
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Publication
23164821 | J:241059
First Author: Killick R
Year: 2014
Journal: Mol Psychiatry
Title: Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.
Volume: 19
Issue: 1
Pages: 88-98
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Protein
D3Z292
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Protein
Q8BJ05
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: false
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Protein
A0A1Y7VK20
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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