Search our database by keyword

Examples

Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 125 out of 125 for Nek4

<< First < Previous | Next > Last >>

0.018s

Type

Details

Score

Protein Domain

IPR031139 | RPGRIP1_fam

Type:

Family

Description:

RPGR-interacting protein 1 (RPGRIP1) is mutated in the eye disease Leber congenital amaurosis (LCA) and its structural homologue, RPGRIP1-like (RPGRIP1L, also called NPHP8 or fantom), is mutated in many different ciliopathies [, ]. Both are multidomain proteins that are predicted to interact with retinitis pigmentosa G-protein regulator (RPGR) []. Both consist of an N-terminal coiled coil domain, two C2 domains (C2N and C2C), and a C-terminal RPGR-interacting domain (RID). RID is a C2 domain with a canonical beta sandwich structure that does not bind Ca2+ and/or phospholipids and thus constitutes a unique type of protein-protein interaction module [].Both RPGRIP1 and RPGRIP1L interact with the ciliary transition zone protein nephrocystin 4 (NPHP4) via their C2C domain [, ]. An hypothesis is that RPGRIP1 and RPGRIP1L function as cilium-specific scaffolds that recruit a Nek4 signaling network which regulates cilium stability []. The expression of RPGRIP1 seems to be limited to photoreceptors and amacrine cells in the retina [], whereas RPGRIP1L is found in other tissues as well.

•

Protein

D6RIK9

Organism:	Mus musculus/domesticus
Length:	211
Fragment?:	false

•

Protein

D3Z0V3

Organism:	Mus musculus/domesticus
Length:	78
Fragment?:	true

•

Protein

A0A1B0GS23

Organism:	Mus musculus/domesticus
Length:	77
Fragment?:	true

•

Publication

17558409 | J:123018

First Author:	Delous M
Year:	2007
Journal:	Nat Genet
Title:	The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome.
Volume:	39
Issue:	7
Pages:	875-81

•

Publication

16339905 | -

First Author:	Roepman R
Year:	2005
Journal:	Proc Natl Acad Sci U S A
Title:	Interaction of nephrocystin-4 and RPGRIP1 is disrupted by nephronophthisis or Leber congenital amaurosis-associated mutations.
Volume:	102
Issue:	51
Pages:	18520-5

•

Protein

M0QWT5

Organism:	Mus musculus/domesticus
Length:	71
Fragment?:	true

•

Protein

A0A1B0GQY2

Organism:	Mus musculus/domesticus
Length:	253
Fragment?:	true

•

Protein

M0QW58

Organism:	Mus musculus/domesticus
Length:	201
Fragment?:	true

•

Protein

M0QWL3

Organism:	Mus musculus/domesticus
Length:	82
Fragment?:	true

•

Protein

M0QWM1

Organism:	Mus musculus/domesticus
Length:	295
Fragment?:	true

•

Protein

Q8CG73

Organism:	Mus musculus/domesticus
Length:	1264
Fragment?:	false

•

Protein

Q9EPQ2

Organism:	Mus musculus/domesticus
Length:	1331
Fragment?:	false

•

Protein

Q0VGR8

Organism:	Mus musculus/domesticus
Length:	1126
Fragment?:	false

•

Protein

E9QQ97

Organism:	Mus musculus/domesticus
Length:	1127
Fragment?:	false

•

Protein

E7CHD7

Organism:	Mus musculus/domesticus
Length:	1320
Fragment?:	false

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

•

Publication

11217851 | J:65060

First Author:	Kawai J
Year:	2001
Journal:	Nature
Title:	Functional annotation of a full-length mouse cDNA collection.
Volume:	409
Issue:	6821
Pages:	685-90

•

Publication

11042159 | J:68323

First Author:	Carninci P
Year:	2000
Journal:	Genome Res
Title:	Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume:	10
Issue:	10
Pages:	1617-30

•

Publication

10349636 | J:80645

First Author:	Carninci P
Year:	1999
Journal:	Methods Enzymol
Title:	High-efficiency full-length cDNA cloning.
Volume:	303

Pages:	19-44

•

Publication

11076861 | J:68324

First Author:	Shibata K
Year:	2000
Journal:	Genome Res
Title:	RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume:	10
Issue:	11
Pages:	1757-71

•

Publication

16141073 | -

First Author:	Katayama S
Year:	2005
Journal:	Science
Title:	Antisense transcription in the mammalian transcriptome.
Volume:	309
Issue:	5740
Pages:	1564-6

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

•

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/keywordSearchResults.do?searchOffset=100&searchTerm=Nek4

MouseMine

Search our database by keyword

Examples

Search results 101 to 125 out of 125 for Nek4

Categories

Hits by Pathway

Hits by Category

Hits by Strain