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Search results 101 to 175 out of 175 for Nfx1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4845112
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3270517
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:4848818
Age: embryonic day 10.5
Note: Staining is present in the progress zone.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4845112
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3270519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848818
Age: embryonic day 11.5
Note: Staining is present in the progress zone and middle limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509937
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5902153
Assay Type: RNA in situ
Annotation Date: 2017-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5902207
Age: embryonic day 14.0
Note: There is ubiquitous staining throughout the embryo.
Specimen Label: 5a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5902153
Assay Type: RNA in situ
Annotation Date: 2017-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5902207
Age: embryonic day 14.0
Note: There is ubiquitous staining throughout the embryo.
Specimen Label: 5b
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5902153
Assay Type: RNA in situ
Annotation Date: 2017-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Ubiquitous
Stage: TS20
Assay Id: MGI:5902207
Age: embryonic day 12.0
Note: There is ubiquitous staining throughout the embryo.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3507149
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540096
Age: embryonic day 15.5
Image: GUDMAP:6690
Specimen Label: GUDMAP:6690
Detected: true
Specimen Num: 1
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Publication
11566096 | J:71637
First Author: Jun L
Year: 2001
Journal: Curr Biol
Title: NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.
Volume: 11
Issue: 18
Pages: 1381-91
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Publication
8703127 | J:35463
First Author: López-Fernández LA
Year: 1996
Journal: Mamm Genome
Title: Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library.
Volume: 7
Issue: 9
Pages: 698-700
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Publication
9464256 | J:45502
First Author: López-Fernández LA
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Tex261, a novel gene presumably related but distinct from steroidogenic acute regulatory (StAR) gene, is regulated during the development of germ cells.
Volume: 242
Issue: 3
Pages: 565-9
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Publication
11331592 | J:92455
First Author: Hsu SI
Year: 2001
Journal: EMBO J
Title: TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.
Volume: 20
Issue: 9
Pages: 2273-85
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR034078 | NFX1_fam
Type: Family
Description: This family of transcription factors is conserved from yeast to human. It is named after human NF-X1, a transcription factor that regulates the expression of class II major histocompatibility complex (MHC) genes [, ]. The Drosophila homologue shuttle craft (STC) has been shown to be a DNA- or RNA-binding protein required for proper axon guidance in the central nervous system []and the yeast homologue FAP1 encodes a dosage suppressor of rapamycin toxicity [].
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Protein
Q8R217
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
Q3ULV1
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q9DAE1
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
E9Q8I7
Organism: Mus musculus/domesticus
Length: 918  
Fragment?: false
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Protein
E9PZN0
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
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Publication
8413274 | -
First Author: Zhang XY
Year: 1993
Journal: Mol Cell Biol
Title: The major histocompatibility complex class II promoter-binding protein RFX (NF-X) is a methylated DNA-binding protein.
Volume: 13
Issue: 11
Pages: 6810-8
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Publication
7964459 | -
First Author: Song Z
Year: 1994
Journal: J Exp Med
Title: A novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressor.
Volume: 180
Issue: 5
Pages: 1763-74
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Publication
8524296 | -
First Author: Stroumbakis ND
Year: 1996
Journal: Mol Cell Biol
Title: A homolog of human transcription factor NF-X1 encoded by the Drosophila shuttle craft gene is required in the embryonic central nervous system.
Volume: 16
Issue: 1
Pages: 192-201
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Publication
10998178 | -
First Author: Kunz J
Year: 2000
Journal: Mol Microbiol
Title: FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.
Volume: 37
Issue: 6
Pages: 1480-93
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Protein
E9Q3K1
Organism: Mus musculus/domesticus
Length: 346  
Fragment?: true
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Protein
B1AY10
Organism: Mus musculus/domesticus
Length: 1114  
Fragment?: false
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Publication
17267499 | -
First Author: Katzenellenbogen RA
Year: 2007
Journal: J Virol
Title: NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.
Volume: 81
Issue: 8
Pages: 3786-96
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Protein Domain
IPR000967 | Znf_NFX1
Type: Domain
Description: Zinc finger (Znf) domains are relatively small protein motifs which contain multiple finger-like protrusions that make tandem contacts with their target molecule. Some of these domains bind zinc, but many do not; instead binding other metals such as iron, or no metal at all. For example, some family members form salt bridges to stabilise the finger-like folds. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis (African clawed frog), however they are now recognised to bind DNA, RNA, protein and/or lipid substrates [, , , , ]. Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. Znf domains are often found in clusters, where fingers can have different binding specificities. There are many superfamilies of Znf motifs, varying in both sequence and structure. They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolvedspecialised functions. For example, Znf-containing proteins function in gene transcription, translation, mRNA trafficking, cytoskeleton organisation, epithelial development, cell adhesion, protein folding, chromatin remodelling and zinc sensing, to name but a few []. Zinc-binding motifs are stable structures, and they rarely undergo conformational changes upon binding their target. This entry represents a domain presumed to be a zinc binding domain. The following pattern describes the zinc finger:C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-Cwhere X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either His or Cys. This central cysteine-rich portion encodes the DNA-binding domain which is highly conserved in eukaryotes []. The NFX1 family of proteins may have additional roles mediated by protein-protein interactions regarding the reiterated RING finger motifs in this central domain which strongly suggest that NFX1 is a probable E3 ubiquitin protein ligase []. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription []; the Drosophila shuttle craft protein, which plays an essential role during the late stages of embryonic neurogenesis and has been shown to be a DNA- or RNA-binding protein []; and the yeast FKBP12-associated protein 1 (FAP1) [].
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Protein
Q8R151
Organism: Mus musculus/domesticus
Length: 1909  
Fragment?: false
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Protein
A2A5R6
Organism: Mus musculus/domesticus
Length: 1045  
Fragment?: false
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Publication
12665246 | -
First Author: Matthews JM
Year: 2002
Journal: IUBMB Life
Title: Zinc fingers--folds for many occasions.
Volume: 54
Issue: 6
Pages: 351-5
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Publication
17210253 | -
First Author: Gamsjaeger R
Year: 2007
Journal: Trends Biochem Sci
Title: Sticky fingers: zinc-fingers as protein-recognition motifs.
Volume: 32
Issue: 2
Pages: 63-70
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Publication
15963892 | -
First Author: Hall TM
Year: 2005
Journal: Curr Opin Struct Biol
Title: Multiple modes of RNA recognition by zinc finger proteins.
Volume: 15
Issue: 3
Pages: 367-73
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Publication
15718139 | -
First Author: Brown RS
Year: 2005
Journal: Curr Opin Struct Biol
Title: Zinc finger proteins: getting a grip on RNA.
Volume: 15
Issue: 1
Pages: 94-8
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Publication
10529348 | -
First Author: Klug A
Year: 1999
Journal: J Mol Biol
Title: Zinc finger peptides for the regulation of gene expression.
Volume: 293
Issue: 2
Pages: 215-8
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Publication
11179890 | -
First Author: Laity JH
Year: 2001
Journal: Curr Opin Struct Biol
Title: Zinc finger proteins: new insights into structural and functional diversity.
Volume: 11
Issue: 1
Pages: 39-46
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