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Search results 101 to 200 out of 1049 for Nkx6-1

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ko HW
Year: 2010
Journal: Dev Cell
Title: Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction.
Volume: 18
Issue: 2
Pages: 237-47
Publication
First Author: Marklund U
Year: 2010
Journal: Development
Title: Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression.
Volume: 137
Issue: 3
Pages: 437-45
Publication
First Author: Ahnfelt-Rønne J
Year: 2012
Journal: Development
Title: Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism.
Volume: 139
Issue: 1
Pages: 33-45
Publication
First Author: Horn S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mind bomb 1 is required for pancreatic β-cell formation.
Volume: 109
Issue: 19
Pages: 7356-61
Publication
First Author: Harrison KA
Year: 1999
Journal: Nat Genet
Title: Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice.
Volume: 23
Issue: 1
Pages: 71-5
Publication
First Author: Cheung HO
Year: 2009
Journal: Sci Signal
Title: The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling.
Volume: 2
Issue: 76
Pages: ra29
Publication
First Author: Wang C
Year: 2013
Journal: J Biol Chem
Title: Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis.
Volume: 288
Issue: 41
Pages: 29518-29
Publication
First Author: Artner I
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: MafB is required for islet beta cell maturation.
Volume: 104
Issue: 10
Pages: 3853-8
Publication
First Author: Nishimura W
Year: 2008
Journal: Dev Biol
Title: Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.
Volume: 314
Issue: 2
Pages: 443-56
Publication
First Author: Mukhopadhyay S
Year: 2013
Journal: Cell
Title: The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Volume: 152
Issue: 1-2
Pages: 210-23
Publication
First Author: Nakatani T
Year: 2007
Journal: Development
Title: Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon.
Volume: 134
Issue: 15
Pages: 2783-93
Publication
First Author: Berbari NF
Year: 2011
Journal: Dev Biol
Title: Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation.
Volume: 360
Issue: 1
Pages: 66-76
Publication
First Author: Heydeck W
Year: 2011
Journal: Dev Dyn
Title: PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube.
Volume: 240
Issue: 8
Pages: 1938-48
Publication
First Author: Dasen JS
Year: 2008
Journal: Cell
Title: Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.
Volume: 134
Issue: 2
Pages: 304-16
Publication
First Author: Ferri AL
Year: 2007
Journal: Development
Title: Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.
Volume: 134
Issue: 15
Pages: 2761-9
Publication
First Author: Gao N
Year: 2008
Journal: Genes Dev
Title: Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
Volume: 22
Issue: 24
Pages: 3435-48
Publication
First Author: Qin J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.
Volume: 108
Issue: 4
Pages: 1456-61
Publication
First Author: Lu QR
Year: 2002
Journal: Cell
Title: Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Volume: 109
Issue: 1
Pages: 75-86
Publication
First Author: Chen MH
Year: 2004
Journal: Genes Dev
Title: Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.
Volume: 18
Issue: 6
Pages: 641-59
Publication
First Author: Gierl MS
Year: 2006
Journal: Genes Dev
Title: The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.
Volume: 20
Issue: 17
Pages: 2465-78
Publication
First Author: Qu J
Year: 2003
Journal: Mol Cell Biol
Title: PAK4 kinase is essential for embryonic viability and for proper neuronal development.
Volume: 23
Issue: 20
Pages: 7122-33
Publication
First Author: Sun T
Year: 2003
Journal: J Neurosci
Title: Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
Volume: 23
Issue: 29
Pages: 9547-56
Publication
First Author: Murdoch JN
Year: 2003
Journal: Mol Cell Neurosci
Title: Genomic organization and embryonic expression of Igsf8, an immunoglobulin superfamily member implicated in development of the nervous system and organ epithelia.
Volume: 22
Issue: 1
Pages: 62-74
Publication
First Author: Jovanovic VM
Year: 2018
Journal: J Neurosci
Title: BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells.
Volume: 38
Issue: 7
Pages: 1662-1676
Publication
First Author: Briscoe J
Year: 2000
Journal: Cell
Title: A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube.
Volume: 101
Issue: 4
Pages: 435-45
Publication
First Author: Damerla RR
Year: 2015
Journal: Hum Mol Genet
Title: Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.
Volume: 24
Issue: 14
Pages: 3994-4005
Publication
First Author: Yan Y
Year: 2009
Journal: Cell
Title: The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2.
Volume: 138
Issue: 6
Pages: 1209-21
Publication
First Author: Smith SB
Year: 2010
Journal: Nature
Title: Rfx6 directs islet formation and insulin production in mice and humans.
Volume: 463
Issue: 7282
Pages: 775-80
Protein
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
Publication
First Author: Lavado A
Year: 2008
Journal: Development
Title: Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.
Volume: 135
Issue: 3
Pages: 441-50
Publication
First Author: Yamanaka Y
Year: 2007
Journal: Dev Cell
Title: Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms.
Volume: 13
Issue: 6
Pages: 884-96
Publication
First Author: Choi MY
Year: 2006
Journal: Development
Title: A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
Volume: 133
Issue: 20
Pages: 4119-29
Publication
First Author: Chaya T
Year: 2014
Journal: EMBO J
Title: ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
Volume: 33
Issue: 11
Pages: 1227-42
Publication
First Author: Christopher KJ
Year: 2012
Journal: Dev Biol
Title: Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.
Volume: 368
Issue: 2
Pages: 382-92
Publication
First Author: Wang C
Year: 2010
Journal: Development
Title: Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.
Volume: 137
Issue: 12
Pages: 2001-9
Publication
First Author: Cameron DA
Year: 2009
Journal: Dev Dyn
Title: Tulp3 is a critical repressor of mouse hedgehog signaling.
Volume: 238
Issue: 5
Pages: 1140-9
Publication
First Author: Norman RX
Year: 2009
Journal: Hum Mol Genet
Title: Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.
Volume: 18
Issue: 10
Pages: 1740-54
Publication
First Author: Bangs F
Year: 2011
Journal: Development
Title: Generation of mice with functional inactivation of talpid3, a gene first identified in chicken.
Volume: 138
Issue: 15
Pages: 3261-72
Publication
First Author: Svärd J
Year: 2006
Journal: Dev Cell
Title: Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.
Volume: 10
Issue: 2
Pages: 187-97
Publication
First Author: Tran PV
Year: 2008
Journal: Nat Genet
Title: THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.
Volume: 40
Issue: 4
Pages: 403-410
Publication
First Author: Kang HS
Year: 2009
Journal: Mol Cell Biol
Title: Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.
Volume: 29
Issue: 24
Pages: 6366-79
Publication
First Author: Persson M
Year: 2002
Journal: Genes Dev
Title: Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity.
Volume: 16
Issue: 22
Pages: 2865-78
Publication
First Author: Schisler JC
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.
Volume: 102
Issue: 20
Pages: 7297-302
Publication
First Author: Mirmira RG
Year: 2000
Journal: J Biol Chem
Title: Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains.
Volume: 275
Issue: 19
Pages: 14743-51
Publication
First Author: Iype T
Year: 2004
Journal: Mol Endocrinol
Title: The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1.
Volume: 18
Issue: 6
Pages: 1363-75
Publication
First Author: Cabrera RM
Year: 2012
Journal: Birth Defects Res A Clin Mol Teratol
Title: Transcriptional analyses of two mouse models of spina bifida.
Volume: 94
Issue: 10
Pages: 782-9
Publication
First Author: Genethliou N
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord.
Volume: 382
Issue: 1
Pages: 69-73
Publication
First Author: Thélie A
Year: 2015
Journal: Development
Title: Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus.
Volume: 142
Issue: 19
Pages: 3416-28
Publication  
First Author: Francius C
Year: 2016
Journal: Front Mol Neurosci
Title: Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.
Volume: 9
Pages: 145
Publication
First Author: Kong JH
Year: 2015
Journal: Dev Cell
Title: Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling.
Volume: 33
Issue: 4
Pages: 373-87
Publication
First Author: Li X
Year: 2014
Journal: Development
Title: Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord.
Volume: 141
Issue: 14
Pages: 2875-84
Publication
First Author: Heller RS
Year: 2004
Journal: Dev Biol
Title: The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity.
Volume: 268
Issue: 1
Pages: 123-34
Publication
First Author: Scardigli R
Year: 2001
Journal: Neuron
Title: Crossregulation between Neurogenin2 and pathways specifying neuronal identity in the spinal cord.
Volume: 31
Issue: 2
Pages: 203-17
Publication
First Author: Panayi H
Year: 2010
Journal: J Neurosci
Title: Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cord.
Volume: 30
Issue: 37
Pages: 12274-80
Publication
First Author: Blaess S
Year: 2008
Journal: Development
Title: Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling.
Volume: 135
Issue: 12
Pages: 2093-103
Publication
First Author: Tuson M
Year: 2011
Journal: Development
Title: Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.
Volume: 138
Issue: 22
Pages: 4921-30
Publication
First Author: Bai CB
Year: 2004
Journal: Dev Cell
Title: All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3.
Volume: 6
Issue: 1
Pages: 103-15
Publication
First Author: Martinelli DC
Year: 2007
Journal: Genes Dev
Title: Gas1 extends the range of Hedgehog action by facilitating its signaling.
Volume: 21
Issue: 10
Pages: 1231-43
Publication
First Author: Oh S
Year: 2009
Journal: Dev Biol
Title: Shh and Gli3 activities are required for timely generation of motor neuron progenitors.
Volume: 331
Issue: 2
Pages: 261-9
Publication
First Author: Yu W
Year: 2008
Journal: Development
Title: Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.
Volume: 135
Issue: 22
Pages: 3687-96
Publication
First Author: Junker JP
Year: 2014
Journal: Dev Cell
Title: A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.
Volume: 31
Issue: 4
Pages: 448-60
Publication
First Author: Han L
Year: 2020
Journal: Nat Commun
Title: Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.
Volume: 11
Issue: 1
Pages: 4158
Publication
First Author: Cai H
Year: 2017
Journal: Dev Biol
Title: Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.
Volume: 432
Issue: 1
Pages: 72-85
Publication
First Author: Yu K
Year: 2013
Journal: Development
Title: Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord.
Volume: 140
Issue: 7
Pages: 1594-604
Publication
First Author: Lei Q
Year: 2004
Journal: Development
Title: Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord.
Volume: 131
Issue: 15
Pages: 3593-604
Publication
First Author: Patterson VL
Year: 2009
Journal: Hum Mol Genet
Title: Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.
Volume: 18
Issue: 10
Pages: 1719-39
Publication  
First Author: Wang Y
Year: 2019
Journal: J Dev Biol
Title: Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia.
Volume: 7
Issue: 1
Publication
First Author: Liu J
Year: 2012
Journal: Dev Biol
Title: Dual function of suppressor of fused in Hh pathway activation and mouse spinal cord patterning.
Volume: 362
Issue: 2
Pages: 141-53
Publication  
First Author: Escuin S
Year: 2023
Journal: Dis Model Mech
Title: Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse.
Volume: 16
Issue: 3
Publication
First Author: Nandadasa S
Year: 2019
Journal: Nat Commun
Title: Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.
Volume: 10
Issue: 1
Pages: 953
Publication
First Author: Mazur MA
Year: 2013
Journal: Diabetes
Title: Microphthalmia transcription factor regulates pancreatic β-cell function.
Volume: 62
Issue: 8
Pages: 2834-42
Publication
First Author: Makino S
Year: 2001
Journal: Dev Biol
Title: A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc).
Volume: 239
Issue: 1
Pages: 95-106
Publication
First Author: Talchai C
Year: 2012
Journal: Cell
Title: Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.
Volume: 150
Issue: 6
Pages: 1223-34
Publication
First Author: Witteveen JS
Year: 2022
Journal: Cell Mol Life Sci
Title: HGprt deficiency disrupts dopaminergic circuit development in a genetic mouse model of Lesch-Nyhan disease.
Volume: 79
Issue: 6
Pages: 341
Publication
First Author: Vermeiren S
Year: 2023
Journal: iScience
Title: Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia.
Volume: 26
Issue: 12
Pages: 108364
Publication
First Author: Vincent M
Year: 2003
Journal: Endocrinology
Title: Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis.
Volume: 144
Issue: 9
Pages: 4061-9
Publication
First Author: Huang X
Year: 2007
Journal: Development
Title: Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord.
Volume: 134
Issue: 11
Pages: 2095-105
Publication
First Author: Lau J
Year: 2010
Journal: Diabetes
Title: Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function.
Volume: 59
Issue: 5
Pages: 1211-21
Publication
First Author: Allen BL
Year: 2007
Journal: Genes Dev
Title: The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
Volume: 21
Issue: 10
Pages: 1244-57
Publication
First Author: Cheng C
Year: 2023
Journal: Sci Adv
Title: Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression.
Volume: 9
Issue: 24
Pages: eadf6927
Publication
First Author: Stottmann RW
Year: 2011
Journal: PLoS Genet
Title: Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo.
Volume: 7
Issue: 9
Pages: e1002224
Publication
First Author: Somatilaka BN
Year: 2020
Journal: Dev Cell
Title: Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling.
Volume: 54
Issue: 6
Pages: 710-726.e8
Publication
First Author: Holtz AM
Year: 2013
Journal: Development
Title: Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
Volume: 140
Issue: 16
Pages: 3423-34
Publication
First Author: Han L
Year: 2012
Journal: J Biol Chem
Title: Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.
Volume: 287
Issue: 24
Pages: 20483-9