Type |
Details |
Score |
Publication |
First Author: |
Egecioglu E |
Year: |
2009 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice. |
Volume: |
297 |
Issue: |
3 |
Pages: |
E708-16 |
|
•
•
•
•
•
|
Allele |
Name: |
neuromedin U; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
neuromedin U; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion RJ32, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 5, Ken-ichi Yagami 2 |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Zeng H |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Neuromedin U receptor 2-deficient mice display differential responses in sensory perception, stress, and feeding. |
Volume: |
26 |
Issue: |
24 |
Pages: |
9352-63 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, coisogenic, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, chromosome aberration, deletion, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
neuromedin U; targeted mutation 1.1, Dimitri De Bundel |
Allele Type: |
Targeted |
Attribute String: |
No functional change, Recombinase |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(5Kit-Nmu)2Utr/+ |
Background: |
C57BL/6JCrlj-Del(5Kit-Nmu)2Utr |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(5Kit-Nmu)2Utr/Del(5Kit-Nmu)2Utr |
Background: |
C57BL/6JCrlj-Del(5Kit-Nmu)2Utr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Torres R |
Year: |
2007 |
Journal: |
Pain |
Title: |
Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses. |
Volume: |
130 |
Issue: |
3 |
Pages: |
267-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peier A |
Year: |
2009 |
Journal: |
Endocrinology |
Title: |
The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2). |
Volume: |
150 |
Issue: |
7 |
Pages: |
3101-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen T |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Structural and functional analogs of the novel mammalian neuropeptide, neuromedin S (NmS), in the dermal venoms of Eurasian bombinid toads. |
Volume: |
345 |
Issue: |
1 |
Pages: |
377-84 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Neuromedin S (NmS) is a neuromedin U-related peptide. It has shown to possess anorexigenic and circadian rhythm-modulating properties in mammals. NmS expression is localised predominantly in the core region of the suprachiasmatic nucleus within the hypothalamus, but also in spleen and testis []. Other biological functions include antidiuretic action via release of vasopressin, milk ejection via release of oxytocin and regulation of the circulatory system, immune reactions and insulin secretion. NmU (neuromedin U) and NmS are involved in thermoregulation via the sympathetic nervous system (beta3 adrenergic receptors) and prostaglandin E2 []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
153
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
153
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
138
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsou AM |
Year: |
2022 |
Journal: |
Nature |
Title: |
Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. |
Volume: |
611 |
Issue: |
7937 |
Pages: |
787-793 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Funes S |
Year: |
2002 |
Journal: |
GenBank Submission |
Title: |
Mus musculus neuromedin U receptor type 2 mRNA, complete cds |
|
|
Pages: |
AY057384 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanada T |
Year: |
2003 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Central actions of neuromedin U via corticotropin-releasing hormone. |
Volume: |
311 |
Issue: |
4 |
Pages: |
954-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim ER |
Year: |
2010 |
Journal: |
Neurosci Lett |
Title: |
Role of neurotensin receptor 1 in the regulation of food intake by neuromedins and neuromedin-related peptides. |
Volume: |
468 |
Issue: |
1 |
Pages: |
64-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Howard AD |
Year: |
2000 |
Journal: |
Nature |
Title: |
Identification of receptors for neuromedin U and its role in feeding. |
Volume: |
406 |
Issue: |
6791 |
Pages: |
70-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jarry AC |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Neuromedin U is a gut peptide that alters oral glucose tolerance by delaying gastric emptying via direct contraction of the pylorus and vagal-dependent mechanisms. |
Volume: |
33 |
Issue: |
4 |
Pages: |
5377-5388 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nesfield SR |
Year: |
2005 |
Journal: |
Int J Toxicol |
Title: |
Evaluation of the carcinogenic potential of clofibrate in the rasH2 mouse. |
Volume: |
24 |
Issue: |
5 |
Pages: |
301-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
von Pressentin MM |
Year: |
1999 |
Journal: |
Carcinogenesis |
Title: |
Mutagenesis induced by oral carcinogens in lacZ mouse (MutaMouse) tongue and other oral tissues. |
Volume: |
20 |
Issue: |
11 |
Pages: |
2167-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nadeau-Vallée M |
Year: |
2016 |
Journal: |
Biol Reprod |
Title: |
Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth. |
Volume: |
95 |
Issue: |
3 |
Pages: |
72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY) |
Year: |
2005 |
Journal: |
Database Download |
Title: |
MGI download of GENSAT transgene data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|