|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 154 out of 154 for Nop10

<< First    < Previous  |  Next >    Last >>
0.022s
Type Details Score
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Protein
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
Protein Domain
Type: Family
Description: H/ACA ribonucleoprotein particles (RNPs) are a family of RNA pseudouridine synthases that specify modification sites through guide RNAs. The function of these H/ACA RNPs is essential for biogenesis of the ribosome, splicing of precursor mRNAs (pre-mRNAs), maintenance of telomeres and probably for additional cellular processes []. All H/ACA RNPs contain a specific RNA component (snoRNA or scaRNA) and at least four proteins common to all such particles: Cbf5, Gar1, Nhp2 and Nop10. These proteins are highly conserved from yeast to mammals and homologues are also present in archaea []. The H/ACA protein complex contains a stable core composed of Cbf5 and Nop10, to which Gar1 and Nhp2 subsequently bind [].In eukaryotes Nop10 is a nucleolar protein that is specifically associated with H/ACA snoRNAs. It is essential for normal 18S rRNA production and rRNA pseudouridylation by the ribonucleoprotein particles containing H/ACA snoRNAs (H/ACA snoRNPs). Nop10 is probably necessary for the stability of these RNPs [].
Protein Domain
Type: Family
Description: Nop10 is a component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs). H/ACA snoRNPs are primarily responsible for catalysing the isomerisation of uridine to pseudouridine (Psi) in ribosomal and other cellular RNAs. The protein component of the H/ACA snoRNP consists of Cbf5, Gar1, Nhp2 and Nop10. The complex contains a stable core composed of Cbf5 and Nop10, to which Gar1 and Nhp2 subsequently bind. Nop10 has an essential role in the assembly and activity of these particles and binds directly to the Cbf5 to form the minimal active enzyme in archaea. The complex interacts with snoRNAs, Nop10 acting as a molecular adaptor for guiding snoRNP assembly [].
Protein Domain
Type: Homologous_superfamily
Description: H/ACA ribonucleoprotein particles (RNPs) are a family of RNA pseudouridine synthases that specify modification sites through guide RNAs. The function of these H/ACA RNPs is essential for biogenesis of the ribosome, splicing of precursor mRNAs (pre-mRNAs), maintenance of telomeres and probably for additional cellular processes []. All H/ACA RNPs contain a specific RNA component (snoRNA or scaRNA) and at least four proteins common to all such particles: Cbf5, Gar1, Nhp2 and Nop10. These proteins are highly conserved from yeast to mammals and homologues are also present in archaea []. The H/ACA protein complex contains a stable core composed of Cbf5 and Nop10, to which Gar1 and Nhp2 subsequently bind [].In eukaryotes Nop10 is a nucleolar protein that is specifically associated with H/ACA snoRNAs. It is essential for normal 18S rRNA production and rRNA pseudouridylation by the ribonucleoprotein particles containing H/ACA snoRNAs (H/ACA snoRNPs). Nop10 is probably necessary for the stability of these RNPs []. The Nop10 domain structure has a rubredoxin-like fold.
Allele    
Name: NOP10 ribonucleoprotein; wild type
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST13205, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST21191, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST68835, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST68842, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST68862, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST72479, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST178964, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST198064, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: NOP10 ribonucleoprotein; gene trap OST432897, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: NOP10 ribonucleoprotein; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: NOP10 ribonucleoprotein; targeted mutation 1.1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: NOP10 ribonucleoprotein; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
Publication
First Author: Henras A
Year: 1998
Journal: EMBO J
Title: Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.
Volume: 17
Issue: 23
Pages: 7078-90
Allele
Name: NOP10 ribonucleoprotein; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Strain
Attribute String: mutant strain, targeted mutation
Strain
Attribute String: coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Nop10/Nop10
Background: C57BL/6N-Nop10/J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Nop10/Nop10<+>
Background: C57BL/6N-Nop10/J
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Meier UT
Year: 2006
Journal: Trends Biochem Sci
Title: How a single protein complex accommodates many different H/ACA RNAs.
Volume: 31
Issue: 6
Pages: 311-5
Publication
First Author: Watanabe Y
Year: 2000
Journal: Nucleic Acids Res
Title: Evolutionary appearance of genes encoding proteins associated with box H/ACA snoRNAs: cbf5p in Euglena gracilis, an early diverging eukaryote, and candidate Gar1p and Nop10p homologs in archaebacteria.
Volume: 28
Issue: 12
Pages: 2342-52
Publication
First Author: Hamma T
Year: 2010
Journal: J Biol Chem
Title: The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification.
Volume: 285
Issue: 2
Pages: 805-9
Publication
First Author: Zou Q
Year: 2021
Journal: iScience
Title: Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.
Volume: 24
Issue: 12
Pages: 103396