Type |
Details |
Score |
Allele |
Name: |
NOP56 ribonucleoprotein; gene trap EUCE0151e07, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
NOP56 ribonucleoprotein; gene trap EUCE0171d11, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
NOP56 ribonucleoprotein; targeted mutation 1, Centre for Modeling Human Disease |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Publication |
First Author: |
McKeegan KS |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
Evidence that the AAA+ proteins TIP48 and TIP49 bridge interactions between 15.5K and the related NOP56 and NOP58 proteins during box C/D snoRNP biogenesis. |
Volume: |
29 |
Issue: |
18 |
Pages: |
4971-81 |
|
•
•
•
•
•
|
Allele |
Name: |
NOP56 ribonucleoprotein; gene trap IST10762F6, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
NOP56 ribonucleoprotein; gene trap IST14342C12, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
NOP56 ribonucleoprotein; gene trap IST14654H11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes a group of pre-RNA processing ribonucleoproteins (RNPs), including Nop56/Nop58 from animals and their homologue, Nop5, from archaea. Proteins in this family contains the Nop domain, which is a RNP binding module, exhibiting RNA and protein binding surfaces. It is oval-shaped and exclusively α-helical [, ]. Nop56 and Nop58 are components of box C/D small nucleolar ribonucleoprotein (snoRNP) particles [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
173
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
60
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hayano T |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Proteomic analysis of human Nop56p-associated pre-ribosomal ribonucleoprotein complexes. Possible link between Nop56p and the nucleolar protein treacle responsible for Treacher Collins syndrome. |
Volume: |
278 |
Issue: |
36 |
Pages: |
34309-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun Q |
Year: |
2017 |
Journal: |
Elife |
Title: |
Molecular architecture of the 90S small subunit pre-ribosome. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This N-terminal domain is found in Nucleolar protein 58/56 from fungi and animals and the homologues form plants. These are RNA-binding proteins of the NOP5 family []. Nop56 and Nop58 are components of box C/D small nucleolar ribonucleoprotein (snoRNP) particles [, ]. This domain interacts with Nop1 and forms the box B/C side, in the case of Nop56, or box C'/D side in the case of Nop58, of U3 snoRNP []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Ryu H |
Year: |
2021 |
Journal: |
EMBO Rep |
Title: |
The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis. |
Volume: |
22 |
Issue: |
6 |
Pages: |
e50684 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gonzales B |
Year: |
2005 |
Journal: |
Hum Mol Genet |
Title: |
The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNA methylation. |
Volume: |
14 |
Issue: |
14 |
Pages: |
2035-43 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
536
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
580
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
580
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
523
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
444
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
191
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
125
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
195
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
222
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
173
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
213
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
135
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
296
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Aittaleb M |
Year: |
2003 |
Journal: |
Nat Struct Biol |
Title: |
Structure and function of archaeal box C/D sRNP core proteins. |
Volume: |
10 |
Issue: |
4 |
Pages: |
256-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu S |
Year: |
2007 |
Journal: |
Science |
Title: |
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. |
Volume: |
316 |
Issue: |
5821 |
Pages: |
115-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Staub E |
Year: |
2004 |
Journal: |
Bioessays |
Title: |
Insights into the evolution of the nucleolus by an analysis of its protein domain repertoire. |
Volume: |
26 |
Issue: |
5 |
Pages: |
567-81 |
|
•
•
•
•
•
|