Type |
Details |
Score |
Publication |
First Author: |
Zhou L |
Year: |
2010 |
Journal: |
FEBS Lett |
Title: |
The nucleoporin Nup153 maintains nuclear envelope architecture and is required for cell migration in tumor cells. |
Volume: |
584 |
Issue: |
14 |
Pages: |
3013-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sistla S |
Year: |
2007 |
Journal: |
Mol Biol Cell |
Title: |
Multiple conserved domains of the nucleoporin Nup124p and its orthologs Nup1p and Nup153 are critical for nuclear import and activity of the fission yeast Tf1 retrotransposon. |
Volume: |
18 |
Issue: |
9 |
Pages: |
3692-708 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Nuclear pore complex protein Nup153 is a component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. The N-terminal domain of Nup153 has NPC targeting activity and is found before the middle domain, which contains four zinc finger motifs of the C2C2-type [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
256
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
203
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
972
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
469
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
98
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
278
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmitz A |
Year: |
2010 |
Journal: |
PLoS Pathog |
Title: |
Nucleoporin 153 arrests the nuclear import of hepatitis B virus capsids in the nuclear basket. |
Volume: |
6 |
Issue: |
1 |
Pages: |
e1000741 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roth P |
Year: |
2003 |
Journal: |
J Cell Biol |
Title: |
The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export. |
Volume: |
163 |
Issue: |
4 |
Pages: |
701-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Nucleoporins (NUP) are the components of the nuclear pore complex (NPC). They can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. The nuclear pore complex constitutes the exclusive means of nucleocytoplasmic transport. NPCs allow the passive diffusion of ions and small molecules and the active, nuclear transport receptor-mediated bidirectional transport of macromolecules such as proteins, RNAs, ribonucleoparticles (RNPs), and ribosomal subunits across the nuclear envelope. NPC is composed of at least 31 different subunits.This family includes nucleoporin Nup121 (Pom121) [], Nup153 []and Nup124 []among others. |
|
•
•
•
•
•
|
Publication |
First Author: |
Souquet B |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells. |
Volume: |
23 |
Issue: |
8 |
Pages: |
2443-2454 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1200
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1200
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
497
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
971
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Vasu S |
Year: |
2001 |
Journal: |
J Cell Biol |
Title: |
Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export. |
Volume: |
155 |
Issue: |
3 |
Pages: |
339-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Terashima Y |
Year: |
2005 |
Journal: |
Nat Immunol |
Title: |
Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis. |
Volume: |
6 |
Issue: |
8 |
Pages: |
827-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harel A |
Year: |
2003 |
Journal: |
Mol Cell |
Title: |
Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. |
Volume: |
11 |
Issue: |
4 |
Pages: |
853-64 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
656
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
280
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
581
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1529
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
274
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Orjalo AV |
Year: |
2006 |
Journal: |
Mol Biol Cell |
Title: |
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly. |
Volume: |
17 |
Issue: |
9 |
Pages: |
3806-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Funakoshi T |
Year: |
2007 |
Journal: |
FEBS Lett |
Title: |
Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes. |
Volume: |
581 |
Issue: |
25 |
Pages: |
4910-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This is a family of nucleoporins conserved from yeast to human.Nup85 Nucleoporin is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol-3-kinase-Rac-lammellipodium protrusion cascade [, , ]. The Nup84 complex is composed of one copy each of Nup84, Nup85, Nup120, Nup133, Nup145C, Sec13, and Seh1. The structure of a complex of Nup85 and Seh1 was solved []. The N terminus of Nup85 is inserted and forms a three-stranded blade that completes the Seh1 6-bladed β-propeller in trans. Following its N-terminal insertion blade, Nup85 forms a compact cuboid structure composed of 20 helices, with two distinct modules, referred to as crown and trunk []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Saito A |
Year: |
2016 |
Journal: |
J Virol |
Title: |
Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo. |
Volume: |
90 |
Issue: |
15 |
Pages: |
6918-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brohawn SG |
Year: |
2008 |
Journal: |
Science |
Title: |
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats. |
Volume: |
322 |
Issue: |
5906 |
Pages: |
1369-73 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1462
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1462
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2085
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
277
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
277
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
666
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
516
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
303
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|