Type |
Details |
Score |
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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•
•
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•
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Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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•
•
•
•
•
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Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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•
•
•
•
•
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Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
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•
•
•
•
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
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•
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•
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Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
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•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
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•
•
•
•
•
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Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
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•
•
•
•
•
|
UniProt Feature |
Begin: |
90 |
Description: |
Required for interaction with NUP50 |
Type: |
site |
End: |
90 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Nuclear pore complex protein Nup50 |
Type: |
chain |
End: |
466 |
|
•
•
•
•
•
|
Publication |
First Author: |
Müller D |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
Cyclin E-mediated elimination of p27 requires its interaction with the nuclear pore-associated protein mNPAP60. |
Volume: |
19 |
Issue: |
10 |
Pages: |
2168-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamura K |
Year: |
2010 |
Journal: |
Plant Cell |
Title: |
Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. |
Volume: |
22 |
Issue: |
12 |
Pages: |
4084-97 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the Ran-binding domain found in plant NUP50 protein. NUP50 is a nuclear pore complex component involved in nucleocytoplasmic transport via its interactions with importins and Ran []. |
|
•
•
•
•
•
|
Allele |
Name: |
nucleoporin 50; targeted mutation 1, Bruce E Clurman |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nup50/Nup50 |
Background: |
involves: 129S4/SvJaeSor * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Megat S |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Integrative genetic analysis illuminates ALS heritability and identifies risk genes. |
Volume: |
14 |
Issue: |
1 |
Pages: |
342 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fabre E |
Year: |
1997 |
Journal: |
Annu Rev Genet |
Title: |
Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking. |
Volume: |
31 |
|
Pages: |
277-313 |
|
•
•
•
•
•
|
Publication |
First Author: |
Loeb JD |
Year: |
1993 |
Journal: |
Mol Biol Cell |
Title: |
NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complex. |
Volume: |
4 |
Issue: |
2 |
Pages: |
209-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pemberton LF |
Year: |
1998 |
Journal: |
Curr Opin Cell Biol |
Title: |
Transport routes through the nuclear pore complex. |
Volume: |
10 |
Issue: |
3 |
Pages: |
392-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Izaurralde E |
Year: |
1998 |
Journal: |
RNA |
Title: |
Transport of macromolecules between the nucleus and the cytoplasm. |
Volume: |
4 |
Issue: |
4 |
Pages: |
351-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hinshaw JE |
Year: |
1994 |
Journal: |
Biochem Pharmacol |
Title: |
Architecture of the nuclear pore complex and its involvement in nucleocytoplasmic transport. |
Volume: |
47 |
Issue: |
1 |
Pages: |
15-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panté N |
Year: |
1996 |
Journal: |
Crit Rev Biochem Mol Biol |
Title: |
Molecular dissection of the nuclear pore complex. |
Volume: |
31 |
Issue: |
2 |
Pages: |
153-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davis LI |
Year: |
1995 |
Journal: |
Annu Rev Biochem |
Title: |
The nuclear pore complex. |
Volume: |
64 |
|
Pages: |
865-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Panté N |
Year: |
1994 |
Journal: |
J Struct Biol |
Title: |
Toward the molecular details of the nuclear pore complex. |
Volume: |
113 |
Issue: |
3 |
Pages: |
179-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rout MP |
Year: |
1993 |
Journal: |
J Cell Biol |
Title: |
Isolation of the yeast nuclear pore complex. |
Volume: |
123 |
Issue: |
4 |
Pages: |
771-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Belanger KD |
Year: |
1994 |
Journal: |
J Cell Biol |
Title: |
Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. |
Volume: |
126 |
Issue: |
3 |
Pages: |
619-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dingwall C |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A family of Ran binding proteins that includes nucleoporins. |
Volume: |
92 |
Issue: |
16 |
Pages: |
7525-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doye V |
Year: |
1995 |
Journal: |
Trends Genet |
Title: |
Genetic approaches to nuclear pore structure and function. |
Volume: |
11 |
Issue: |
6 |
Pages: |
235-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Newmeyer DD |
Year: |
1993 |
Journal: |
Curr Opin Cell Biol |
Title: |
The nuclear pore complex and nucleocytoplasmic transport. |
Volume: |
5 |
Issue: |
3 |
Pages: |
395-407 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents a domain found in Nup2, 50 and 61, which are components of the nuclear pore complex. Nucleoporin 50kDa (NUP50) acts as a cofactor for the importin-alpha:importin-beta heterodimer, which in turn allows for transportation of many nuclear-targeted proteins through nuclear pore complexes. The C terminus of NUP50 binds importin-beta through RAN-GTP, the N terminus binds the C terminus of importin-alpha, while a central domain binds importin-beta. NUP50:importin-alpha:importin-beta then binds cargo and can stimulate nuclear import. The N-terminal domain of NUP50 is also able to actively displace nuclear localisation signals from importin-alpha []. NUP2 encodes a non-essential nuclear pore protein that has a central domain similar to those of Nsp1 and Nup1[, ]. Transport of macromolecules between the nucleus and the cytoplasm of eukaryotic cells occurs through the nuclear pore complex (NPC), a large macromolecular complex that spans the nuclear envelope [, , ]. The structure of the vertebrate NPC has been studied extensively; recent reviews include [, , , ]. The yeast NPC shares several features with the vertebrate NPC, despite being smaller and less elaborate [, ]. Many yeast nuclear pore proteins, or nucleoporins, have been identified by a variety of genetic approaches [, , , ]. nup2 mutants show genetic interactions with nsp1 and nup1 conditional alleles [, ]. Nup1 interacts with the nuclear import factor Srp1 []and with the small GTPase Ran (encoded by GSP1) []. |
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•
•
•
•
•
|
Publication |
First Author: |
Doye V |
Year: |
1997 |
Journal: |
Curr Opin Cell Biol |
Title: |
From nucleoporins to nuclear pore complexes. |
Volume: |
9 |
Issue: |
3 |
Pages: |
401-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shang J |
Year: |
2017 |
Journal: |
Neuroscience |
Title: |
Aberrant distributions of nuclear pore complex proteins in ALS mice and ALS patients. |
Volume: |
350 |
|
Pages: |
158-168 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Q |
Year: |
1998 |
Journal: |
Mol Cell |
Title: |
Three-dimensional architecture of the isolated yeast nuclear pore complex: functional and evolutionary implications. |
Volume: |
1 |
Issue: |
2 |
Pages: |
223-34 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
440
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Park J |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. |
Volume: |
50 |
Issue: |
6 |
Pages: |
919-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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•
•
•
•
•
|