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Search results 101 to 200 out of 344 for Opn4

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Type Details Score
Publication
20808732 | J:167927
 
First Author: Berkowitz BA
Year: 2010
Journal: Mol Vis
Title: Light-dependant intraretinal ion regulation by melanopsin in young awake and free moving mice evaluated with manganese-enhanced MRI.
Volume: 16
Pages: 1776-80
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Publication
16488873 | J:106309
First Author: Barnard AR
Year: 2006
Journal: Curr Biol
Title: Melanopsin regulates visual processing in the mouse retina.
Volume: 16
Issue: 4
Pages: 389-95
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Publication
20855606 | J:165419
First Author: Johnson J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Melanopsin-dependent light avoidance in neonatal mice.
Volume: 107
Issue: 40
Pages: 17374-8
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Publication
22547062 | J:333495
First Author: Sexton TJ
Year: 2012
Journal: J Biol Chem
Title: Melanopsin is highly resistant to light and chemical bleaching in vivo.
Volume: 287
Issue: 25
Pages: 20888-97
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Publication
12481140 | J:81502
First Author: Ruby NF
Year: 2002
Journal: Science
Title: Role of melanopsin in circadian responses to light.
Volume: 298
Issue: 5601
Pages: 2211-3
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Publication
19513122 | J:150652
First Author: Tsai JW
Year: 2009
Journal: PLoS Biol
Title: Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice.
Volume: 7
Issue: 6
Pages: e1000125
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Publication
38224335 | J:344373
First Author: Matynia A
Year: 2024
Journal: Invest Ophthalmol Vis Sci
Title: Preservation of Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) in Late Adult Mice: Implications as a Potential Biomarker for Early Onset Ocular Degenerative Diseases.
Volume: 65
Issue: 1
Pages: 28
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Publication
29249284 | J:256019
First Author: Stabio ME
Year: 2018
Journal: Neuron
Title: The M5 Cell: A Color-Opponent Intrinsically Photosensitive Retinal Ganglion Cell.
Volume: 97
Issue: 1
Pages: 150-163.e4
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Publication
27162356 | J:232174
First Author: Fernandez DC
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Architecture of retinal projections to the central circadian pacemaker.
Volume: 113
Issue: 21
Pages: 6047-52
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Publication
23151476 | J:189957
First Author: LeGates TA
Year: 2012
Journal: Nature
Title: Aberrant light directly impairs mood and learning through melanopsin-expressing neurons.
Volume: 491
Issue: 7425
Pages: 594-8
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Publication
26070985 | J:230779
 
First Author: Matynia A
Year: 2015
Journal: Exp Eye Res
Title: Light aversion and corneal mechanical sensitivity are altered by intrinscally photosensitive retinal ganglion cells in a mouse model of corneal surface damage.
Volume: 137
Pages: 57-62
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Publication
18480363 | J:256960
First Author: Schmidt TM
Year: 2008
Journal: J Neurophysiol
Title: Intrinsic and extrinsic light responses in melanopsin-expressing ganglion cells during mouse development.
Volume: 100
Issue: 1
Pages: 371-84
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Publication
12487121 | J:80439
First Author: Bellingham J
Year: 2002
Journal: Brain Res Mol Brain Res
Title: Zebrafish melanopsin: isolation, tissue localisation and phylogenetic position.
Volume: 107
Issue: 2
Pages: 128-36
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Publication
23796782 | J:201175
First Author: van Diepen HC
Year: 2013
Journal: FASEB J
Title: Irradiance encoding in the suprachiasmatic nuclei by rod and cone photoreceptors.
Volume: 27
Issue: 10
Pages: 4204-12
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Publication
24678795 | J:215952
First Author: Blasic JR Jr
Year: 2014
Journal: Biochemistry
Title: Identification of critical phosphorylation sites on the carboxy tail of melanopsin.
Volume: 53
Issue: 16
Pages: 2644-9
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Publication
25401926 | J:225305
First Author: Cameron EG
Year: 2014
Journal: PLoS One
Title: β-Arrestin-dependent deactivation of mouse melanopsin.
Volume: 9
Issue: 11
Pages: e113138
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Publication
35675393 | J:326083
First Author: Liu AL
Year: 2022
Journal: Sci Adv
Title: The role of ipRGCs in ocular growth and myopia development.
Volume: 8
Issue: 23
Pages: eabm9027
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619817
Stage: TS17
Assay Id: MGI:3027608
Age: embryonic day 10.5
Specimen Label: E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:3027608
Age: embryonic day 11.5
Specimen Label: E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619820
Stage: TS20
Assay Id: MGI:3027608
Age: embryonic day 12.5
Specimen Label: E12.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619821
Stage: TS21
Assay Id: MGI:3027608
Age: embryonic day 13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
       
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:3027608
Age: embryonic day 14.5
Specimen Label: E14.5
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619823
Stage: TS23
Assay Id: MGI:3027608
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:3027608
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:3027608
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619827
Stage: TS27
Assay Id: MGI:3027608
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 9
Specimen Label: P9
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
     
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
       
Probe: MGI:3027512
Assay Type: RT-PCR
Annotation Date: 2004-02-12
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3027608
Age: postnatal adult
Specimen Label: Adult
Specimen Num: 18
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529027
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 0
Image: 5 P0
Note: Authors report expression in axons throughout lateral geniculate nucleus from birth.
Specimen Label: 5 P0
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 4
Image: 5 P4
Note: Authors report expression in axons throughout lateral geniculate nucleus from birth.
Specimen Label: 5 P4
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 7
Image: 5 P7
Note: Authors report expression in axons throughout lateral geniculate nucleus from birth.
Specimen Label: 5 P7
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
Probe: MGI:7482244
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7482280
Age: postnatal day 9
Image: 7D
Note: Expression in differentiated intrinsically photosensitive retinal ganglion cells (ipRGCs).
Specimen Label: 7D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7482244
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7482280
Age: postnatal day 9
Image: 7E
Note: Significant reduction in ipRGC density in dorsal and nasal/temporal petals, but not in ventral petals.
Specimen Label: 7E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6192522
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1859022
Stage: TS22
Assay Id: MGI:6192523
Age: embryonic day 14.0
Image: 1D E14
Specimen Label: 1D E14
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6192522
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6192523
Age: embryonic day 15.0
Image: 1D E15
Note: Authors report expression begins at E15.
Specimen Label: 1D E15
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1859022
Stage: TS22
Assay Id: MGI:6192525
Age: embryonic day 14.0
Image: 1F E14
Note: Authors report complete absence of expression at E14.
Specimen Label: 1F E14
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6192525
Age: embryonic day 15.0
Image: 1F E15
Note: Authors report expression begins at E15. Some expressing cells detected in ganglion cell layer; others appear to be migrating from neuroblast layer to ganglion cell layer.
Specimen Label: 1F E15
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6192525
Age: embryonic day 15.0
Image: 1G E15
Note: Authors report no expression in peripheral retina at E15.
Specimen Label: 1G E15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6192525
Age: embryonic day 16.0
Image: 1G E16
Note: Subsequent expansion of the region of expressing cells.
Specimen Label: 1G E16
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859026
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6192525
Age: embryonic day 18.0
Image: 1G E18
Note: Subsequent expansion of the region of expressing cells.
Specimen Label: 1G E18
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859027
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 0
Image: 1G P0
Note: Authors report periphery is entirely filled in by P0.
Specimen Label: 1G P0
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3277827
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 0
Image: 4C P0
Note: No expression in olivary pretectal nucleus.
Specimen Label: 4C P0
Detected: false
Specimen Num: 20
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GXD Expression
GXD Expression
 
Probe: MGI:6414622
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6414629
Age: embryonic day 16.5
Note: Expression in ganglion cell layer of wild type retina.
Specimen Label: 2A/A'
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6414622
Assay Type: RNA in situ
Annotation Date: 2020-05-04
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3574224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6414629
Age: embryonic day 16.5
Note: Expression significantly reduced in central ganglion cell layer.
Specimen Label: 2B/B'
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7482244
Assay Type: Immunohistochemistry
Annotation Date: 2023-05-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7482280
Age: postnatal day 30
Image: 7G
Note: Difference persisted at P30.
Specimen Label: 7G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 0
Image: 2C P0
Note: Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
Specimen Label: 2C P0
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 4
Image: 2C P4
Note: Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
Specimen Label: 2C P4
Detected: true
Specimen Num: 8
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 7
Image: 2C P7
Note: Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
Specimen Label: 2C P7
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 14
Image: 2C P14
Note: Expression in intrinsically photosensitive retinal ganglion cells (ipRGCs).
Specimen Label: 2C P14
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584125
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6192525
Age: embryonic day 17.0
Image: 3 E17
Note: Expression in chiasm on ventral surface as early as E17.
Specimen Label: 3 E17
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 2
Image: 3 P2
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P2
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 3
Image: 3 P3
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P3
Detected: true
Specimen Num: 14
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 4
Image: 3 P4
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P4
Detected: true
Specimen Num: 15
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•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 1
Image: 3 P1
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P1
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 6
Image: 3 P6
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P6
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 14
Image: 3 P14
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P14
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 21
Image: 3 P21
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P21
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3584128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 49
Image: 3 P49
Note: Serial sections from brains at different time points show spatial and termporal progression of intrinsically photosensitive retinal ganglion cell (ipRGC) innervation of the suprachiasmatic nucleus (SCN).
Specimen Label: 3 P49
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3590827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6192525
Age: postnatal day 0
Image: 5 P0
Note: Authors report expression in axons throughout lateral geniculate nucleus from birth.
Specimen Label: 5 P0
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3590828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 4
Image: 5 P4
Note: Authors report expression in axons throughout lateral geniculate nucleus from birth.
Specimen Label: 5 P4
Detected: true
Specimen Num: 25
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3590828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 7
Image: 5 P7
Note: Authors report expression in axons throughout lateral geniculate nucleus from birth.
Specimen Label: 5 P7
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757526
Stage: TS26
Assay Id: MGI:6192525
Age: embryonic day 18.0
Image: 1G E18
Note: No expression in central optic nerve.
Specimen Label: 1G E18
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3792128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 7
Image: 4C P7
Note: Faint expression in shell starting at P7.
Specimen Label: 4C P7
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3792128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 10
Image: 4C P10
Specimen Label: 4C P10
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2018-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3792128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6192525
Age: postnatal day 14
Image: 4C P14
Note: Authors report adult-like innervation by P14.
Specimen Label: 4C P14
Detected: true
Specimen Num: 23
•
•
•
•
•
Publication
31255486 | J:284539
First Author: Bray ER
Year: 2019
Journal: Neuron
Title: Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells.
Volume: 103
Issue: 4
Pages: 642-657.e7
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•
•
•
•
Publication
36669474 | J:344596
First Author: Meng JJ
Year: 2023
Journal: Cell
Title: Light modulates glucose metabolism by a retina-hypothalamus-brown adipose tissue axis.
Volume: 186
Issue: 2
Pages: 398-412.e17
•
•
•
•
•
Publication
38697114 | J:348674
     
First Author: Fitzpatrick MJ
Year: 2024
Journal: Neuron
Title: A pupillary contrast response in mice and humans: Neural mechanisms and visual functions.
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•
•
•
Publication
27669145 | J:238084
   
First Author: Keenan WT
Year: 2016
Journal: Elife
Title: A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction.
Volume: 5
•
•
•
•
•
Publication
36280260 | J:332235
First Author: Brock O
Year: 2022
Journal: J Neurosci
Title: A role for thalamic projection GABAergic neurons in circadian responses to light.
Volume: 42
Issue: 49
Pages: 9158-79
•
•
•
•
•
Publication
31784286 | J:283413
First Author: Tran NM
Year: 2019
Journal: Neuron
Title: Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes.
Volume: 104
Issue: 6
Pages: 1039-1055.e12
•
•
•
•
•
Publication
38733989 | J:348776
First Author: Toma K
Year: 2024
Journal: Cell
Title: Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.
Volume: 187
Issue: 11
Pages: 2767-2784.e23
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•
•
•
Publication
30995485 | J:281028
First Author: Kiyama T
Year: 2019
Journal: Cell Rep
Title: Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.
Volume: 27
Issue: 3
Pages: 900-915.e5
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•
•
•
•
Publication
23255724 | J:238046
First Author: Atkinson CL
Year: 2013
Journal: J Neurophysiol
Title: Functional integrity and modification of retinal dopaminergic neurons in the rd1 mutant mouse: roles of melanopsin and GABA.
Volume: 109
Issue: 6
Pages: 1589-99
•
•
•
•
•
Publication
26438865 | J:225942
First Author: Storchi R
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.
Volume: 112
Issue: 42
Pages: E5734-43
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•
•
•
•
Publication
31924821 | J:291616
First Author: Roy D
Year: 2020
Journal: Sci Rep
Title: Rhodopsin and melanopsin coexist in mammalian sperm cells and activate different signaling pathways for thermotaxis.
Volume: 10
Issue: 1
Pages: 112
•
•
•
•
•
Publication
31825819 | J:300917
First Author: Lee SK
Year: 2019
Journal: Cell Rep
Title: M1 Intrinsically Photosensitive Retinal Ganglion Cells Integrate Rod and Melanopsin Inputs to Signal in Low Light.
Volume: 29
Issue: 11
Pages: 3349-3355.e2
•
•
•
•
•
Publication
26218912 | J:230952
First Author: González-Menéndez I
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Influence of Opa1 Mutation on Survival and Function of Retinal Ganglion Cells.
Volume: 56
Issue: 8
Pages: 4835-45
•
•
•
•
•
Publication
17329208 | J:128662
First Author: Dkhissi-Benyahya O
Year: 2007
Journal: Neuron
Title: Modeling the role of mid-wavelength cones in circadian responses to light.
Volume: 53
Issue: 5
Pages: 677-87
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•
•
•
•
Publication
16687291 | J:124726
First Author: Lupi D
Year: 2006
Journal: Chronobiol Int
Title: Light-evoked FOS induction within the suprachiasmatic nuclei (SCN) of melanopsin knockout (Opn4-/-) mice: a developmental study.
Volume: 23
Issue: 1-2
Pages: 167-79
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•
•
•
•
Publication
19160505 | J:141041
First Author: Lupi D
Year: 2008
Journal: Nat Neurosci
Title: The acute light-induction of sleep is mediated by OPN4-based photoreception.
Volume: 11
Issue: 9
Pages: 1068-73
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•
Publication
33536197 | J:304039
First Author: Zhou W
Year: 2021
Journal: J Neurosci
Title: Orexin-A Intensifies Mouse Pupillary Light Response by Modulating Intrinsically Photosensitive Retinal Ganglion Cells.
Volume: 41
Issue: 12
Pages: 2566-2580
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•
Publication
18695249 | J:139704
First Author: Doyle SE
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retinal pathways influence temporal niche.
Volume: 105
Issue: 35
Pages: 13133-8
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Publication
30587542 | J:271675
First Author: Lin MS
Year: 2019
Journal: J Neurosci
Title: Degeneration of ipRGCs in Mouse Models of Huntington's Disease Disrupts Non-Image-Forming Behaviors Before Motor Impairment.
Volume: 39
Issue: 8
Pages: 1505-1524
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•
Publication
28103478 | J:256142
First Author: Storchi R
Year: 2017
Journal: Neuron
Title: Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.
Volume: 93
Issue: 2
Pages: 299-307
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Publication
16788070 | J:111699
First Author: Doyle SE
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Nonvisual light responses in the Rpe65 knockout mouse: rod loss restores sensitivity to the melanopsin system.
Volume: 103
Issue: 27
Pages: 10432-7
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Publication
35870522 | J:328276
 
First Author: Hunyara JL
Year: 2022
Journal: Exp Neurol
Title: Characterization of non-alpha retinal ganglion cell injury responses reveals a possible block to restoring ipRGC function.
Volume: 357
Pages: 114176
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Publication
22771039 | J:199506
First Author: van Oosterhout F
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Journal: Curr Biol
Title: Ultraviolet light provides a major input to non-image-forming light detection in mice.
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Publication
12752778 | J:128149
First Author: Semo M
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Journal: Eur J Neurosci
Title: Melanopsin retinal ganglion cells and the maintenance of circadian and pupillary responses to light in aged rodless/coneless (rd/rd cl) mice.
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Publication
12481141 | J:81501
First Author: Panda S
Year: 2002
Journal: Science
Title: Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting.
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Issue: 5601
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21808002 | J:175610
First Author: Warthen DM
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Journal: Proc Natl Acad Sci U S A
Title: Light enhances learned fear.
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Pages: 13788-93
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Publication
16364902 | J:107606
First Author: Tu DC
Year: 2005
Journal: Neuron
Title: Physiologic diversity and development of intrinsically photosensitive retinal ganglion cells.
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Issue: 6
Pages: 987-99
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Publication
17325172 | J:123259
First Author: Zhu Y
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: Melanopsin-dependent persistence and photopotentiation of murine pupillary light responses.
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Publication
26011287 | J:237743
First Author: Aytürk DG
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Journal: PLoS One
Title: Lack of Melanopsin Is Associated with Extreme Weight Loss in Mice upon Dietary Challenge.
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Pages: e0127031
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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