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Search results 101 to 147 out of 147 for Parg

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Type Details Score
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
29894693 | J:262541
First Author: Gogola E
Year: 2018
Journal: Cancer Cell
Title: Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Volume: 33
Issue: 6
Pages: 1078-1093.e12
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Publication
14622405 | -
First Author: Golovanov AP
Year: 2003
Journal: Mol Microbiol
Title: ParG, a protein required for active partition of bacterial plasmids, has a dimeric ribbon-helix-helix structure.
Volume: 50
Issue: 4
Pages: 1141-53
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Protein Domain
IPR015354 | DNA_partition_ParG
Type: Family
Description: This entry represents plasmid partition proteins; it adopts a ribbon-helix-helix fold, with a core of four α-helices. The proteins are an essential component of the DNA partition complex of the multi drug resistance plasmid TP228 [].
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Allele
Parg<em1Smoc> | MGI:7291533
Name: poly (ADP-ribose) glycohydrolase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein Domain
IPR046372 | PARG_cat
Type: Domain
Description: Poly(ADP-ribose) glycohydrolase (PARG) () is a ubiquitously expressed exo- and endoglycohydrolase which catalyses the hydrolysis of the O-glycosidic linkages of ADP-ribose polymers, reversing the effects of poly(ADP-ribose) [, , , , ]. It generates mono-ADP-ribosylated proteins in cells, due to its ability of degrading poly(ADP-ribose) without cleaving the terminal protein-ribose bond []. PARG is also involved in the synthesis of nuclear ATP, which is required for extensive chromatin remodeling events []. This protein mediates oxidative and excitotoxic neuronal death [].Arabidopsis thaliana PARG1 is involved in abiotic stress responses and DNA repair [, ].This entry represents the catalytic domain of PARG from animals, plants and some fungal species.
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Protein
O88622
Organism: Mus musculus/domesticus
Length: 969  
Fragment?: false
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Protein
G3X8U8
Organism: Mus musculus/domesticus
Length: 961  
Fragment?: false
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Protein
Q3TUI8
Organism: Mus musculus/domesticus
Length: 577  
Fragment?: true
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Protein
A0A2I3BRU5
Organism: Mus musculus/domesticus
Length: 661  
Fragment?: false
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Protein
E9Q088
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
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Publication
11593040 | -
First Author: Ying W
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death.
Volume: 98
Issue: 21
Pages: 12227-32
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Publication
23251397 | -
First Author: Tucker JA
Year: 2012
Journal: PLoS One
Title: Structures of the human poly (ADP-ribose) glycohydrolase catalytic domain confirm catalytic mechanism and explain inhibition by ADP-HPD derivatives.
Volume: 7
Issue: 12
Pages: e50889
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Publication
22609859 | -
First Author: Kim IK
Year: 2012
Journal: Nat Struct Mol Biol
Title: Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.
Volume: 19
Issue: 6
Pages: 653-6
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Publication
33186521 | -
First Author: Bonfiglio JJ
Year: 2020
Journal: Cell
Title: An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation.
Volume: 183
Issue: 4
Pages: 1086-1102.e23
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Publication
34019811 | -
First Author: Prokhorova E
Year: 2021
Journal: Mol Cell
Title: Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease.
Volume: 81
Issue: 12
Pages: 2640-2655.e8
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Publication
34321462 | -
First Author: Rack JGM
Year: 2021
Journal: Nat Commun
Title: Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal.
Volume: 12
Issue: 1
Pages: 4581
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Publication
27257257 | -
First Author: Wright RH
Year: 2016
Journal: Science
Title: ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling.
Volume: 352
Issue: 6290
Pages: 1221-5
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Publication
34592134 | -
First Author: Kong L
Year: 2021
Journal: Mol Cell
Title: Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity.
Volume: 81
Issue: 22
Pages: 4591-4604.e8
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Publication
26516022 | -
 
First Author: Zhang H
Year: 2015
Journal: Sci Rep
Title: Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation.
Volume: 5
Pages: 15892
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HT Experiment
GSE248429 | PARP1 knockout mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Domain
IPR007724 | Poly_GlycHdrlase
Type: Family
Description: Poly(ADP-ribose) glycohydrolase (PARG) () is a ubiquitously expressed exo- and endoglycohydrolase which catalyses the hydrolysis of the O-glycosidic linkages of ADP-ribose polymers, reversing the effects of poly(ADP-ribose) [, , , , ]. It generates mono-ADP-ribosylated proteins in cells, due to its ability of degrading poly(ADP-ribose) without cleaving the terminal protein-ribose bond []. PARG is also involved in the synthesis of nuclear ATP, which is required for extensive chromatin remodeling events []. This protein mediates oxidative and excitotoxic neuronal death [].Arabidopsis thaliana PARG1 is involved in abiotic stress responses and DNA repair [, ].
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Publication
17645773 | J:138108
First Author: Miwa M
Year: 2007
Journal: Cancer Sci
Title: PolyADP-ribosylation and cancer.
Volume: 98
Issue: 10
Pages: 1528-35
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Publication
23116180 | J:193994
First Author: Guastafierro T
Year: 2013
Journal: Biochem J
Title: ADP-ribose polymer depletion leads to nuclear Ctcf re-localization and chromatin rearrangement(1).
Volume: 449
Issue: 3
Pages: 623-30
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Publication
31326434 | J:286114
 
First Author: Chen L
Year: 2019
Journal: Biochem Pharmacol
Title: Development of renal failure in PargParp-1 null and Timm23 hypomorphic mice.
Volume: 167
Pages: 116-124
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Publication
31996026 | J:304886
First Author: Karshovska E
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: HIF-1α (Hypoxia-Inducible Factor-1α) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383.
Volume: 40
Issue: 3
Pages: 583-596
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Publication
39056235 | J:361044
 
First Author: Karpova Y
Year: 2024
Journal: G3 (Bethesda)
Title: Adaptive genetic mechanisms in mammalian Parp1 locus.
Volume: 14
Issue: 9
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