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Search results 101 to 200 out of 454 for Pbsn

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Type Details Score
Publication
First Author: Chen Z
Year: 2009
Journal: Sci Signal
Title: Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
Volume: 2
Issue: 84
Pages: ra44
Publication
First Author: Zhou Z
Year: 2006
Journal: Cancer Res
Title: Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer.
Volume: 66
Issue: 16
Pages: 7889-98
Publication
First Author: Ding Z
Year: 2011
Journal: Nature
Title: SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.
Volume: 470
Issue: 7333
Pages: 269-73
Publication
First Author: Francis JC
Year: 2010
Journal: PLoS Genet
Title: Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.
Volume: 6
Issue: 6
Pages: e1000995
Strain
Attribute String: transgenic, targeted mutation, mutant stock
Publication
First Author: Ko HK
Year: 2014
Journal: Cancer Res
Title: A transgenic mouse model for early prostate metastasis to lymph nodes.
Volume: 74
Issue: 3
Pages: 945-53
Publication
First Author: Buñay J
Year: 2023
Journal: Oncogene
Title: Persistent organic pollutants promote aggressiveness in prostate cancer.
Volume: 42
Issue: 38
Pages: 2854-2867
Publication
First Author: Rasool RU
Year: 2023
Journal: Nat Commun
Title: Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.
Volume: 14
Issue: 1
Pages: 5253
Publication
First Author: Antoch MP
Year: 2020
Journal: Oncotarget
Title: Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer.
Volume: 11
Issue: 15
Pages: 1373-1387
Publication
First Author: Francis JC
Year: 2024
Journal: Oncogene
Title: Identification of genes that promote PI3K pathway activation and prostate tumour formation.
Volume: 43
Issue: 24
Pages: 1824-1835
Publication
First Author: Ting MC
Year: 2012
Journal: Dis Model Mech
Title: An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice.
Volume: 5
Issue: 3
Pages: 366-74
Publication
First Author: Le B
Year: 2017
Journal: PLoS One
Title: Multi-drug loaded micelles delivering chemotherapy and targeted therapies directed against HSP90 and the PI3K/AKT/mTOR pathway in prostate cancer.
Volume: 12
Issue: 3
Pages: e0174658
Publication
First Author: Wang S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation.
Volume: 103
Issue: 5
Pages: 1480-5
Publication
First Author: Francis JC
Year: 2018
Journal: Oncotarget
Title: SOX9 is a driver of aggressive prostate cancer by promoting invasion, cell fate and cytoskeleton alterations and epithelial to mesenchymal transition.
Volume: 9
Issue: 7
Pages: 7604-7615
Publication
First Author: Tang S
Year: 2012
Journal: Cancer Res
Title: Increased CD8+ T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells.
Volume: 72
Issue: 8
Pages: 1975-85
Publication
First Author: Hsieh AC
Year: 2012
Journal: Nature
Title: The translational landscape of mTOR signalling steers cancer initiation and metastasis.
Volume: 485
Issue: 7396
Pages: 55-61
Publication
First Author: Lerman I
Year: 2017
Journal: Mol Cancer Res
Title: Infiltrating Myeloid Cells Exert Protumorigenic Actions via Neutrophil Elastase.
Volume: 15
Issue: 9
Pages: 1138-1152
Publication
First Author: Wang S
Year: 2003
Journal: Cancer Cell
Title: Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer.
Volume: 4
Issue: 3
Pages: 209-21
Publication
First Author: Conley-LaComb MK
Year: 2012
Journal: Am J Pathol
Title: PTEN regulates PDGF ligand switch for β-PDGFR signaling in prostate cancer.
Volume: 180
Issue: 3
Pages: 1017-27
Publication
First Author: Akins EJ
Year: 2010
Journal: Cancer Res
Title: In situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice.
Volume: 70
Issue: 9
Pages: 3473-82
Publication
First Author: Narayanan NK
Year: 2009
Journal: Int J Cancer
Title: Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice.
Volume: 125
Issue: 1
Pages: 1-8
Publication
First Author: Schwartz S
Year: 2015
Journal: Cancer Cell
Title: Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.
Volume: 27
Issue: 1
Pages: 109-22
Publication
First Author: Wang C
Year: 2020
Journal: FASEB J
Title: PTEN deletion drives aberrations of DNA methylome and transcriptome in different stages of prostate cancer.
Volume: 34
Issue: 1
Pages: 1304-1318
Publication
First Author: Berquin IM
Year: 2005
Journal: J Biol Chem
Title: Expression signature of the mouse prostate.
Volume: 280
Issue: 43
Pages: 36442-51
Publication  
First Author: Krolewski JJ
Year: 2022
Journal: Cancers (Basel)
Title: TNF Signaling Is Required for Castration-Induced Vascular Damage Preceding Prostate Cancer Regression.
Volume: 14
Issue: 24
Publication
First Author: Lerman I
Year: 2019
Journal: Mol Cancer Res
Title: Epigenetic Suppression of SERPINB1 Promotes Inflammation-Mediated Prostate Cancer Progression.
Volume: 17
Issue: 4
Pages: 845-859
Publication
First Author: Zhang J
Year: 2020
Journal: Prostate
Title: Proteomic and transcriptomic profiling of Pten gene-knockout mouse model of prostate cancer.
Volume: 80
Issue: 7
Pages: 588-605
Publication  
First Author: Hu X
Year: 2015
Journal: Sci Rep
Title: Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis.
Volume: 5
Pages: 15182
Publication
First Author: Okeyo-Owuor T
Year: 2017
Journal: PLoS One
Title: Exposure to maternal obesogenic diet worsens some but not all pre-cancer phenotypes in a murine genetic model of prostate cancer.
Volume: 12
Issue: 5
Pages: e0175764
Publication
First Author: Kim S
Year: 2022
Journal: Prostate
Title: Aqueous metabolome of tissue-specific conditional Pten-knockout mouse prostate cancer and TRAMP neuroendocrine carcinoma.
Volume: 82
Issue: 1
Pages: 154-166
Publication
First Author: Goel HL
Year: 2012
Journal: Cancer Discov
Title: VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer.
Volume: 2
Issue: 10
Pages: 906-21
Publication
First Author: Garcia AJ
Year: 2014
Journal: Mol Cell Biol
Title: Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression.
Volume: 34
Issue: 11
Pages: 2017-28
Publication  
First Author: Pan C
Year: 2020
Journal: JCI Insight
Title: Prostate tumor-derived GDF11 accelerates androgen deprivation therapy-induced sarcopenia.
Volume: 5
Issue: 6
Publication
First Author: Allott EH
Year: 2018
Journal: Prostate Cancer Prostatic Dis
Title: Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer.
Volume: 21
Issue: 2
Pages: 196-203
Publication
First Author: Zhang W
Year: 2009
Journal: Cancer Res
Title: Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.
Volume: 69
Issue: 18
Pages: 7466-72
Publication
First Author: Wang L
Year: 2014
Journal: Cell Rep
Title: Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth.
Volume: 8
Issue: 5
Pages: 1461-74
Publication
First Author: Chen Y
Year: 2013
Journal: Nat Med
Title: ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss.
Volume: 19
Issue: 8
Pages: 1023-9
Publication
First Author: Blattner M
Year: 2017
Journal: Cancer Cell
Title: SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.
Volume: 31
Issue: 3
Pages: 436-451
Publication
First Author: Zhu C
Year: 2011
Journal: J Biol Chem
Title: Conditional expression of the androgen receptor induces oncogenic transformation of the mouse prostate.
Volume: 286
Issue: 38
Pages: 33478-88
Publication
First Author: Dai B
Year: 2006
Journal: Cancer Res
Title: Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse.
Volume: 66
Issue: 16
Pages: 8058-64
Publication
First Author: Moussavi M
Year: 2010
Journal: Cancer Res
Title: Oncolysis of prostate cancers induced by vesicular stomatitis virus in PTEN knockout mice.
Volume: 70
Issue: 4
Pages: 1367-76
Publication
First Author: Igelmann S
Year: 2021
Journal: Mol Cell
Title: A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Volume: 81
Issue: 18
Pages: 3848-3865.e19
Publication
First Author: Huang J
Year: 2002
Journal: Cancer Res
Title: Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium.
Volume: 62
Issue: 16
Pages: 4812-9
Publication
First Author: Mao GE
Year: 2012
Journal: Prostate
Title: A joint effect of new Western diet and retinoid X receptor α prostate-specific knockout with development of high-grade prostatic intraepithelial neoplasia in mice--a preliminary study.
Volume: 72
Issue: 10
Pages: 1052-9
Strain
Attribute String: mutant strain, targeted mutation, transgenic
Publication
First Author: Triscott J
Year: 2023
Journal: Sci Adv
Title: PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition.
Volume: 9
Issue: 5
Pages: eade8641
Publication
First Author: Sengiku A
Year: 2018
Journal: Sci Rep
Title: Circadian coordination of ATP release in the urothelium via connexin43 hemichannels.
Volume: 8
Issue: 1
Pages: 1996
Publication
First Author: Wang L
Year: 2009
Journal: Cancer Cell
Title: Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate.
Volume: 16
Issue: 4
Pages: 336-46
Publication
First Author: Liu B
Year: 2020
Journal: Oncotarget
Title: Evidence for context-dependent functions of KDM5B in prostate development and prostate cancer.
Volume: 11
Issue: 46
Pages: 4243-4252
Publication
First Author: Alvarez-Arzola R
Year: 2023
Journal: Cell Commun Signal
Title: VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer.
Volume: 21
Issue: 1
Pages: 76
Publication
First Author: Kelavkar UP
Year: 2006
Journal: Neoplasia
Title: Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model.
Volume: 8
Issue: 6
Pages: 510-22
Publication
First Author: Xing C
Year: 2013
Journal: PLoS One
Title: Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells.
Volume: 8
Issue: 6
Pages: e65538
Publication
First Author: Nguyen AH
Year: 2013
Journal: Hum Mol Genet
Title: Gata3 antagonizes cancer progression in Pten-deficient prostates.
Volume: 22
Issue: 12
Pages: 2400-10
Publication
First Author: Wang G
Year: 2013
Journal: Nat Genet
Title: Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Volume: 45
Issue: 7
Pages: 739-746
Publication
First Author: Lunardi A
Year: 2013
Journal: Nat Genet
Title: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.
Volume: 45
Issue: 7
Pages: 747-55
Publication
First Author: Grbesa I
Year: 2021
Journal: Cell Rep
Title: Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity.
Volume: 36
Issue: 10
Pages: 109625
Publication
First Author: González-Billalabeitia E
Year: 2014
Journal: Cancer Discov
Title: Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.
Volume: 4
Issue: 8
Pages: 896-904
Publication
First Author: Karantanos T
Year: 2013
Journal: Cancer Cell
Title: GEMMs shine a light on resistance to androgen deprivation therapy for prostate cancer.
Volume: 24
Issue: 1
Pages: 11-3
Publication
First Author: Bousset L
Year: 2020
Journal: PLoS Biol
Title: Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.
Volume: 18
Issue: 12
Pages: e3000948
Publication
First Author: Chen Z
Year: 2005
Journal: Nature
Title: Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Volume: 436
Issue: 7051
Pages: 725-30
Publication
First Author: Shoag J
Year: 2018
Journal: J Clin Invest
Title: SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.
Volume: 128
Issue: 1
Pages: 381-386
Publication
First Author: Dardenne E
Year: 2016
Journal: Cancer Cell
Title: N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Volume: 30
Issue: 4
Pages: 563-577
Publication
First Author: Pascal LE
Year: 2017
Journal: J Endocrinol
Title: Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia.
Volume: 235
Issue: 2
Pages: 123-136
Publication
First Author: Shinde D
Year: 2019
Journal: Eur Urol Oncol
Title: Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer.
Volume: 2
Issue: 4
Pages: 415-424
Publication
First Author: Fang L
Year: 2022
Journal: Cancer Gene Ther
Title: TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence.
Volume: 29
Issue: 10
Pages: 1463-1476
Publication
First Author: Elfandy H
Year: 2019
Journal: Mol Cancer Res
Title: Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.
Volume: 17
Issue: 2
Pages: 446-456
Publication
First Author: Nardella C
Year: 2009
Journal: Sci Signal
Title: Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Volume: 2
Issue: 55
Pages: ra2
Publication
First Author: Patnaik A
Year: 2017
Journal: Cancer Discov
Title: Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity.
Volume: 7
Issue: 7
Pages: 750-765
Publication
First Author: Wegner KA
Year: 2020
Journal: J Pathol
Title: Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation.
Volume: 250
Issue: 2
Pages: 231-242
Publication
First Author: Chen M
Year: 2018
Journal: Nat Genet
Title: An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Volume: 50
Issue: 2
Pages: 206-218
Publication
First Author: Bainor AJ
Year: 2017
Journal: Cancer Res
Title: Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Volume: 77
Issue: 19
Pages: 5339-5348
Publication
First Author: MartĂ­n-MartĂ­n N
Year: 2018
Journal: Cancer Res
Title: PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth.
Volume: 78
Issue: 2
Pages: 399-409
Publication
First Author: Wiles WG 4th
Year: 2014
Journal: In Vivo
Title: Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality.
Volume: 28
Issue: 5
Pages: 709-18
Publication
First Author: Liu R
Year: 2015
Journal: Cancer Res
Title: FOXP3-miR-146-NF-ÎşB Axis and Therapy for Precancerous Lesions in Prostate.
Volume: 75
Issue: 8
Pages: 1714-24
Publication
First Author: Pascal LE
Year: 2019
Journal: Neoplasia
Title: Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice.
Volume: 21
Issue: 8
Pages: 752-764
Publication
First Author: Zhang L
Year: 2010
Journal: Stem Cells
Title: Dicer ablation impairs prostate stem cell activity and causes prostate atrophy.
Volume: 28
Issue: 7
Pages: 1260-9
Publication
First Author: Albino D
Year: 2021
Journal: Commun Biol
Title: Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer.
Volume: 4
Issue: 1
Pages: 119
Publication
First Author: Calcinotto A
Year: 2018
Journal: Nature
Title: IL-23 secreted by myeloid cells drives castration-resistant prostate cancer.
Volume: 559
Issue: 7714
Pages: 363-369
Publication  
First Author: Xiong X
Year: 2012
Journal: Oncogenesis
Title: Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice.
Volume: 1
Pages: e26
Publication
First Author: Wang H
Year: 2018
Journal: Carcinogenesis
Title: δ-Tocopherol inhibits the development of prostate adenocarcinoma in prostate specific Pten-/- mice.
Volume: 39
Issue: 2
Pages: 158-169
Publication
First Author: Wozniak DJ
Year: 2017
Journal: Nat Commun
Title: PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Volume: 8
Issue: 1
Pages: 1508
Publication
First Author: Sun X
Year: 2014
Journal: Neoplasia
Title: Deletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways.
Volume: 16
Issue: 5
Pages: 377-89
Publication  
First Author: Hermanova I
Year: 2020
Journal: J Exp Med
Title: Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.
Volume: 217
Issue: 6
Publication
First Author: Zoma M
Year: 2021
Journal: Nat Commun
Title: EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer.
Volume: 12
Issue: 1
Pages: 4147
Publication
First Author: Xie Y
Year: 2014
Journal: Mol Endocrinol
Title: Crosstalk between nuclear MET and SOX9/β-catenin correlates with castration-resistant prostate cancer.
Volume: 28
Issue: 10
Pages: 1629-39
Publication
First Author: Malek M
Year: 2017
Journal: Mol Cell
Title: PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
Volume: 68
Issue: 3
Pages: 566-580.e10
Genotype
Symbol: Pten/Pten Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Rxra/Rxra<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Rxra/Rxra Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Pbsn-cre)4Prb/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pik3cb/Pik3cb Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pik3ca/Pik3ca Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kras/Kras<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Brca2/Brca2 Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Brca2/Brca2 Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true