| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_22 |
|
| Specimen Label: |
euxassay_002518_22 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_23 |
|
| Specimen Label: |
euxassay_002518_23 |
| Detected: |
true |
| Specimen Num: |
23 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1715823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_11 |
|
| Specimen Label: |
euxassay_002518_11 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1715823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_12 |
|
| Specimen Label: |
euxassay_002518_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1715823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_13 |
|
| Specimen Label: |
euxassay_002518_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_07 |
|
| Specimen Label: |
euxassay_002518_07 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679523 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_08 |
|
| Specimen Label: |
euxassay_002518_08 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_10 |
|
| Specimen Label: |
euxassay_002518_10 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_11 |
|
| Specimen Label: |
euxassay_002518_11 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_12 |
|
| Specimen Label: |
euxassay_002518_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_13 |
|
| Specimen Label: |
euxassay_002518_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_14 |
|
| Specimen Label: |
euxassay_002518_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_15 |
|
| Specimen Label: |
euxassay_002518_15 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_16 |
|
| Specimen Label: |
euxassay_002518_16 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679823 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_18 |
|
| Specimen Label: |
euxassay_002518_18 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_02 |
|
| Specimen Label: |
euxassay_002518_02 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_03 |
|
| Specimen Label: |
euxassay_002518_03 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_04 |
|
| Specimen Label: |
euxassay_002518_04 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_05 |
|
| Specimen Label: |
euxassay_002518_05 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_06 |
|
| Specimen Label: |
euxassay_002518_06 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_07 |
|
| Specimen Label: |
euxassay_002518_07 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_08 |
|
| Specimen Label: |
euxassay_002518_08 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_09 |
|
| Specimen Label: |
euxassay_002518_09 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_10 |
|
| Specimen Label: |
euxassay_002518_10 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_11 |
|
| Specimen Label: |
euxassay_002518_11 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_12 |
|
| Specimen Label: |
euxassay_002518_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_13 |
|
| Specimen Label: |
euxassay_002518_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_14 |
|
| Specimen Label: |
euxassay_002518_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_15 |
|
| Specimen Label: |
euxassay_002518_15 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_16 |
|
| Specimen Label: |
euxassay_002518_16 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_17 |
|
| Specimen Label: |
euxassay_002518_17 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_18 |
|
| Specimen Label: |
euxassay_002518_18 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_19 |
|
| Specimen Label: |
euxassay_002518_19 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_20 |
|
| Specimen Label: |
euxassay_002518_20 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_21 |
|
| Specimen Label: |
euxassay_002518_21 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_22 |
|
| Specimen Label: |
euxassay_002518_22 |
| Detected: |
true |
| Specimen Num: |
22 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1054469 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
| Pattern: |
Uniform |
| Stage: |
TS23 |
| Assay Id: |
MGI:4827168 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_002518_23 |
|
| Specimen Label: |
euxassay_002518_23 |
| Detected: |
true |
| Specimen Num: |
23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Di Nardo A |
| Year: |
2000 |
| Journal: |
GenBank Submission |
| Title: |
Mus musculus mRNA for profilin II (pfn2 gene) |
|
|
| Pages: |
AJ272203 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waites CL |
| Year: |
2011 |
| Journal: |
J Neurosci |
| Title: |
Piccolo regulates the dynamic assembly of presynaptic F-actin. |
| Volume: |
31 |
| Issue: |
40 |
| Pages: |
14250-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ni T |
| Year: |
2020 |
| Journal: |
Sci Adv |
| Title: |
Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. |
| Volume: |
6 |
| Issue: |
5 |
| Pages: |
eaax8286 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouneimne G |
| Year: |
2012 |
| Journal: |
Cancer Cell |
| Title: |
Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
615-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Widada JS |
| Year: |
1989 |
| Journal: |
Nucleic Acids Res |
| Title: |
Total coding sequence of profilin cDNA from Mus musculus macrophage. |
| Volume: |
17 |
| Issue: |
7 |
| Pages: |
2855 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Witke W |
| Year: |
2001 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Profilin I is essential for cell survival and cell division in early mouse development. |
| Volume: |
98 |
| Issue: |
7 |
| Pages: |
3832-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bowerman M |
| Year: |
2009 |
| Journal: |
Mol Cell Neurosci |
| Title: |
SMN, profilin IIa and plastin 3: a link between the deregulation of actin dynamics and SMA pathogenesis. |
| Volume: |
42 |
| Issue: |
1 |
| Pages: |
66-74 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang X |
| Year: |
1999 |
| Journal: |
J Cell Biol |
| Title: |
Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin. |
| Volume: |
147 |
| Issue: |
1 |
| Pages: |
151-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lederer M |
| Year: |
2005 |
| Journal: |
J Cell Sci |
| Title: |
Profilin regulates the activity of p42POP, a novel Myb-related transcription factor. |
| Volume: |
118 |
| Issue: |
Pt 2 |
| Pages: |
331-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nölle A |
| Year: |
2011 |
| Journal: |
Hum Mol Genet |
| Title: |
The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin. |
| Volume: |
20 |
| Issue: |
24 |
| Pages: |
4865-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Michaelsen-Preusse K |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Neuronal profilins in health and disease: Relevance for spine plasticity and Fragile X syndrome. |
| Volume: |
113 |
| Issue: |
12 |
| Pages: |
3365-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miyagi Y |
| Year: |
2002 |
| Journal: |
J Neurosci |
| Title: |
Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor delta 2 subunit. |
| Volume: |
22 |
| Issue: |
3 |
| Pages: |
803-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang Y |
| Year: |
2014 |
| Journal: |
Cell Rep |
| Title: |
H3K36 histone methyltransferase Setd2 is required for murine embryonic stem cell differentiation toward endoderm. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
1989-2002 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kullmann JA |
| Year: |
2011 |
| Journal: |
EMBO Rep |
| Title: |
Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
75-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Oishi H |
| Year: |
2005 |
| Journal: |
Arthritis Rheum |
| Title: |
Accelerating effect of an MRL gene locus on the severity and onset of arthropathy in DBA/1 mice. |
| Volume: |
52 |
| Issue: |
3 |
| Pages: |
959-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gareus R |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
Mouse profilin 2 regulates endocytosis and competes with SH3 ligand binding to dynamin 1. |
| Volume: |
281 |
| Issue: |
5 |
| Pages: |
2803-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lin Q |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life. |
| Volume: |
114 |
| Issue: |
34 |
| Pages: |
9188-9193 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lambrechts A |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains. |
| Volume: |
275 |
| Issue: |
46 |
| Pages: |
36143-51 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Di Domenico M |
| Year: |
2021 |
| Journal: |
Cells |
| Title: |
Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure. |
| Volume: |
10 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang R |
| Year: |
2020 |
| Journal: |
J Cell Biol |
| Title: |
NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesis. |
| Volume: |
219 |
| Issue: |
1 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vasilopoulou E |
| Year: |
2016 |
| Journal: |
Kidney Int |
| Title: |
Loss of endogenous thymosin β4 accelerates glomerular disease. |
| Volume: |
90 |
| Issue: |
5 |
| Pages: |
1056-1070 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Osmundsen H |
| Year: |
2007 |
| Journal: |
Arch Oral Biol |
| Title: |
Changes in gene-expression during development of the murine molar tooth germ. |
| Volume: |
52 |
| Issue: |
9 |
| Pages: |
803-13 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Morris DJ |
| Year: |
1993 |
| Journal: |
Genomics |
| Title: |
Somatic cell hybrid mapping on mouse chromosome 11 (MMU11): assignment of markers relative to two breakpoints in band D. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
323-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schilling K |
| Year: |
2009 |
| Journal: |
Cerebellum |
| Title: |
The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
477-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Velocigene |
| Year: |
2008 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Figley MD |
| Year: |
2014 |
| Journal: |
J Neurosci |
| Title: |
Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics. |
| Volume: |
34 |
| Issue: |
24 |
| Pages: |
8083-97 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Profilins (PFNs) are a group of small eukaryotic proteins that bind to monomeric actin (G-actin) in a 1:1 ratio thus preventing the polymerisation of actin into filaments (F-actin). They can also in certain circumstance promote actin polymerisation. Profilins also bind to polyphosphoinositides such as PIP2 []. Other ligands include members of the Ena/VASP and formin families []. Overall sequence similarity among profilin from organisms which belong to different phyla (ranging from fungi to mammals) is low, but the N-terminal region is relatively well conserved. The N-terminal region is thought to be involved in actin binding. Four Profilins have been identified in mammals, PFN1-4. PFN1 and PFN2 differentially regulate membrane protrusion, motility, and invasion; these processes are promoted by PFN1 and suppressed by PFN2 []. This entry represents PFN1. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yu X |
| Year: |
2022 |
| Journal: |
EMBO J |
| Title: |
Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation. |
| Volume: |
41 |
| Issue: |
23 |
| Pages: |
e111857 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
112
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
140
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
55
 |
| Fragment?: |
false |
|
•
•
•
•
•
|