Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3834708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-03-09 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3614125 |
|
Stage: |
TS25 |
Assay Id: |
MGI:3834863 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
E18 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3834708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-03-09 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3614127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3834863 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
1d |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3834708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-03-09 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3614125 |
|
Stage: |
TS25 |
Assay Id: |
MGI:3834869 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
E18 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3834708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-03-09 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3614127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3834869 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
1d |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3834708 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-03-09 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3614127 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3834868 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
3d |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3834707 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-03-06 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1881225 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:3834720 |
Age: |
embryonic day 17.5 |
|
Note: |
Expression is present in the proacinar cells but not in the ductal cells. |
Specimen Label: |
3C |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Windass JD |
Year: |
1984 |
Journal: |
Nucleic Acids Res |
Title: |
Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands. |
Volume: |
12 |
Issue: |
3 |
Pages: |
1361-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maruyama EO |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands. |
Volume: |
11 |
Issue: |
1 |
Pages: |
e0146711 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
SO Term |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Publication |
First Author: |
Bortoff KD |
Year: |
1997 |
Journal: |
Endocrine |
Title: |
Insulin induction of pip 92, CL-6, and novel mRNAs in rat hepatoma cells. |
Volume: |
7 |
Issue: |
2 |
Pages: |
199-207 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun M |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Control of Rab7a activity and localization through endosomal type Igamma PIP 5-kinase is required for endosome maturation and lysosome function. |
Volume: |
34 |
Issue: |
2 |
Pages: |
2730-2748 |
|
•
•
•
•
•
|
Allele |
Name: |
prolactin induced protein; targeted mutation 1.1, Catherine E Ovitt |
Allele Type: |
Targeted |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
prolactin induced protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
308
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Lokuta MA |
Year: |
2007 |
Journal: |
Mol Biol Cell |
Title: |
Type Igamma PIP kinase is a novel uropod component that regulates rear retraction during neutrophil chemotaxis. |
Volume: |
18 |
Issue: |
12 |
Pages: |
5069-80 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
450
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
449
 |
Fragment?: |
false |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2097
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
497
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2052
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sekiya M |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function. |
|
|
Pages: |
112914 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents archaeal Nre proteins. While most archaeal organisms encode only a single Nre protein, some encode two, NreA and NreB.NreA is an archaeal PCNA interacting protein that works together with the UvrABC proteins in repairing DNA damage resulting from exposure to DNA damaging agent MMC. NreA contains a putative PIP motif at its C terminus that is important for its function []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
142
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This conserved region is found in the N-terminal region of archaeal Nre proteins. While most archaeal organisms encode only a single Nre protein, some encode two, NreA and NreB. NreA is an archaeal PCNA interacting protein that works together with the UvrABC proteins in repairing DNA damage resulting from exposure to DNA damaging agent MMC. NreA contains a putative PIP motif at its C terminus that is important for its function []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This conserved region is found in the C-terminal region of archaeal Nre proteins. While most archaeal organisms encode only a single Nre protein, some encode two, NreA and NreB. NreA is an archaeal PCNA interacting protein that works together with the UvrABC proteins in repairing DNA damage resulting from exposure to DNA damaging agent MMC. NreA contains a putative PIP motif atits C terminus that is important for its function []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Myotubularin-related protein 14 (MTMR14, also known as Jumpy) belongs to the myotubularin family, whose members are dual-specificity phosphatases that act primarily to dephosphorylate phosphoinositides (PIs). They act specifically on PI3P and PI3,5P2, dephosphorylating them to form PIP and PI5P, respectively []. MTMR14 interacts with early autophagosomes and negatively regulates progression through the steps of autophagy []. It has been linked to the a congenital muscle disorder known as myopathy, centronuclear, 1 (CNM1) []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Giroux X |
Year: |
2016 |
Journal: |
Mol Microbiol |
Title: |
A novel archaeal DNA repair factor that acts with the UvrABC system to repair mitomycin C-induced DNA damage in a PCNA-dependent manner. |
Volume: |
99 |
Issue: |
1 |
Pages: |
1-14 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Myotubularin-related protein 14 (MTMR14, also known as Jumpy) belongs to the myotubularin family, whose members are dual-specificity phosphatases that act primarily to dephosphorylate phosphoinositides (PIs). They act specifically on PI3P and PI3,5P2, dephosphorylating them to form PIP and PI5P, respectively []. MTMR14 interacts with early autophagosomes and negatively regulates progression through the steps of autophagy []. It has been linked to the a congenital muscle disorder known as myopathy, centronuclear, 1 (CNM1) [].MTMR14 contain a N-terminal PH-GRAM domain, a Rac-induced recruitment domain (RID) domain, an active PTP domain, a SET-interaction domain (SID), a coiled-coil region, and a C-terminal PDZ domain. This entry represents the PH-GRAM domain that binds to phosphoinositide lipid []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Tosch V |
Year: |
2006 |
Journal: |
Hum Mol Genet |
Title: |
A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy. |
Volume: |
15 |
Issue: |
21 |
Pages: |
3098-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vergne I |
Year: |
2009 |
Journal: |
EMBO J |
Title: |
Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy. |
Volume: |
28 |
Issue: |
15 |
Pages: |
2244-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown AL |
Year: |
1999 |
Journal: |
Hum Mol Genet |
Title: |
Bex1, a gene with increased expression in parthenogenetic embryos, is a member of a novel gene family on the mouse X chromosome. |
Volume: |
8 |
Issue: |
4 |
Pages: |
611-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pearsall GB |
Year: |
1997 |
Journal: |
Dev Neurosci |
Title: |
Jimpy-4J mouse has a missense mutation in exon 2 of the Plp gene. |
Volume: |
19 |
Issue: |
4 |
Pages: |
337-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2008 |
Journal: |
Mol Biol Cell |
Title: |
The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals. |
Volume: |
19 |
Issue: |
7 |
Pages: |
3080-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Legate KR |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis. |
Volume: |
30 |
Issue: |
22 |
Pages: |
4539-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang CC |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. |
Volume: |
7 |
|
Pages: |
12135 |
|
•
•
•
•
•
|
Publication |
First Author: |
Badger CC |
Year: |
1990 |
Journal: |
Int J Rad Appl Instrum B |
Title: |
Biodistribution of p-iodobenzoyl (PIP) labeled antibodies in a murine lymphoma model. |
Volume: |
17 |
Issue: |
4 |
Pages: |
381-7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
331
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
189
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2018 |
Journal: |
Cell Res |
Title: |
Structure of the human activated spliceosome in three conformational states. |
Volume: |
28 |
Issue: |
3 |
Pages: |
307-322 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
The mature U2 snRNP (small nuclear ribonucleoprotein particle) relies on the spliceosome assembly for its function, which involves the Splicing factor 3a (SF3a), an evolutionary eukaryotic conserved heterotrimeric complex, essential for pre-mRNA splicing []. This complex includes three subunits: SF3a60, SF3a66 and SF3a120 in the human complex, being Prp9, Prp11 and Prp21 the counterparts in Saccharomyces cerevisiae. SF3a60 possess a highly conserved C2H2-type zinc-finger domain at the C-terminal, while Prp9 has two such domains; SF3a66 and Prp11 contain one C2H2-type zinc-finger domain and SF3a120/Prp21 has two suppressor-of-white-apricot and prp21/spp91 (SURP) domains, followed by a short segment of charged residues. The SURP2 domain of SF3a120/Prp21 has a role in SF3a60/Prp9 binding, however, SURP1 domain function is unknown. The yeast structure shows that Prp9 interacts with Prp21 via a bidentate-binding mode, and Prp21 is wrapped around Prp11 [].This entry represents the C-terminal region of SF3a60 subunit (also known as SF3a3 and Spliceosome-associated protein 61 or Prp9 from yeast) from SF3a complex, found in eukaryotes. This domain has two conserved sequence motifs: PIP and CEICG. It contains a zinc-finger domain of the C2H2-type which might be important for RNA binding and protein-protein interactions with components of the SF3b complex []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Rampazzo C |
Year: |
2002 |
Journal: |
Gene |
Title: |
Mouse cytosolic and mitochondrial deoxyribonucleotidases: cDNA cloning of the mitochondrial enzyme, gene structures, chromosomal mapping and comparison with the human orthologs. |
Volume: |
294 |
Issue: |
1-2 |
Pages: |
109-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Korrodi-Gregório L |
Year: |
2013 |
Journal: |
Biol Open |
Title: |
TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network. |
Volume: |
2 |
Issue: |
5 |
Pages: |
453-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eisenbeis CF |
Year: |
1995 |
Journal: |
Genes Dev |
Title: |
Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator. |
Volume: |
9 |
Issue: |
11 |
Pages: |
1377-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yeung YG |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
A novel macrophage actin-associated protein (MAYP) is tyrosine-phosphorylated following colony stimulating factor-1 stimulation. |
Volume: |
273 |
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Protein |
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Mus musculus/domesticus |
Length: |
140
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
264
 |
Fragment?: |
true |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
264
 |
Fragment?: |
true |
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