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Search results 101 to 200 out of 216 for Plk3

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 42
Image: g01204 Adult
Specimen Label: g01204 Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945664
Age: embryonic day 11.5
Image: g01204 E11.5
Specimen Label: g01204 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 7
Image: g01204 P7
Specimen Label: g01204 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 42
Image: g01204 Adult
Specimen Label: g01204 Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1681608
Assay Type: RNA in situ
Annotation Date: 2024-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7575841
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the subventricular zone.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 7
Image: g01204 P7
Specimen Label: g01204 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 42
Image: g01204 Adult
Specimen Label: g01204 Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 7
Image: g01204 P7
Note: Expression was region specific and scattered.
Specimen Label: g01204 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 42
Image: g01204 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01204 Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945664
Age: embryonic day 15.5
Image: g01204 E15.5
Specimen Label: g01204 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945664
Age: embryonic day 15.5
Image: g01204 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01204 E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 7
Image: g01204 P7
Note: Expression was region specific and scattered.
Specimen Label: g01204 P7
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:4885384
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945664
Age: postnatal day 42
Image: g01204 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01204 Adult
Detected: true
Specimen Num: 4
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Publication
21264284 | J:169464
First Author: Kostyak JC
Year: 2011
Journal: PLoS One
Title: Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells.
Volume: 6
Issue: 1
Pages: e14513
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Publication
34107258 | J:306624
First Author: Liu F
Year: 2021
Journal: Cell Rep
Title: miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3.
Volume: 35
Issue: 10
Pages: 109225
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Publication
22854038 | J:199766
First Author: Jordan PW
Year: 2012
Journal: J Cell Sci
Title: Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes.
Volume: 125
Issue: Pt 21
Pages: 5061-72
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Publication
21574244 | J:174238
First Author: Rorick NK
Year: 2011
Journal: Am J Med Genet A
Title: Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.
Volume: 155A
Issue: 6
Pages: 1314-21
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Protein
Q60806
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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Publication
15890332 | J:99698
First Author: Abramova N
Year: 2005
Journal: Dev Biol
Title: Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.
Volume: 283
Issue: 2
Pages: 269-81
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Publication
32758484 | J:297664
First Author: Simonson L
Year: 2020
Journal: Dev Biol
Title: Keratin 13 deficiency causes white sponge nevus in mice.
Volume: 468
Issue: 1-2
Pages: 146-153
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR020658 | Ser/Thr_kinase_PLK3
Type: Family
Description: PLK3 (polo-like kinase 3) is a serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly [, , ]. It regulates angiogenesis and responses to DNA damage []. Activated PLK3 mediates Chk2 phosphorylation by ATM and the resulting checkpoint activation []. PLK3 phosphorylates DNA polymerase delta and may be involved in DNA repair. It also inhibits Cdc25c, thereby regulating the onset of mitosis [, ].
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HT Experiment
GSE75279 | Expression data from postnatal Plk3 WT and KO animals
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE75381 | Expression data from embryonic Plk3 WT and KO animals
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q60806-2
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 49
Description: Phosphoserine; by PLK3
Type: modified residue
End: 49
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UniProt Feature
UniProt Feature
Begin: 589
Description: Phosphoserine; by PLK3
Type: modified residue
End: 589
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UniProt Feature
UniProt Feature
Begin: 668
Description: Phosphoserine; by PLK3
Type: modified residue
End: 668
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UniProt Feature
UniProt Feature
Begin: 509
Description: Phosphoserine; by PLK3
Type: modified residue
End: 509
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UniProt Feature
UniProt Feature
Begin: 503
Description: Phosphoserine; by PLK3
Type: modified residue
End: 503
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UniProt Feature
UniProt Feature
Begin: 213
Description: Phosphoserine; by PLK3
Type: modified residue
End: 213
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UniProt Feature
UniProt Feature
Begin: 220
Description: Phosphoserine; by PLK3
Type: modified residue
End: 220
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UniProt Feature
UniProt Feature
Begin: 71
Description: Phosphoserine; by PLK3
Type: modified residue
End: 71
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UniProt Feature
UniProt Feature
Begin: 82
Description: Phosphoserine; by PLK3
Type: modified residue
End: 82
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase PLK3
Type: chain
End: 631
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UniProt Feature
UniProt Feature
Begin: 342
Description: Phosphoserine; by PLK3
Type: modified residue
End: 342
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Publication
15640846 | -
First Author: Myer DL
Year: 2005
Journal: Oncogene
Title: The Plk3-Cdc25 circuit.
Volume: 24
Issue: 2
Pages: 299-305
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Publication
17568195 | -
First Author: Zimmerman WC
Year: 2007
Journal: Cell Cycle
Title: Finding Plk3.
Volume: 6
Issue: 11
Pages: 1314-8
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Publication
23210979 | -
First Author: Xu D
Year: 2012
Journal: Exp Hematol Oncol
Title: Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.
Volume: 1
Issue: 1
Pages: 5
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UniProt Feature
UniProt Feature
Begin: 73
Description: Phosphoserine; by MAPK8 and PLK3
Type: modified residue
End: 73
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UniProt Feature
UniProt Feature
Begin: 718
Description: Phosphoserine; by PLK2 and PLK3
Type: modified residue
End: 718
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UniProt Feature
UniProt Feature
Begin: 366
Description: Phosphothreonine; by GSK3-beta and PLK3
Type: modified residue
End: 366
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UniProt Feature
UniProt Feature
Begin: 370
Description: Phosphoserine; by CK2 and PLK3
Type: modified residue
End: 370
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Publication
11039900 | -
First Author: Holtrich U
Year: 2000
Journal: Oncogene
Title: Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages.
Volume: 19
Issue: 42
Pages: 4832-9
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Publication
9677325 | -
 
First Author: Chase D
Year: 1998
Journal: Biochem J
Title: Expression and phosphorylation of fibroblast-growth-factor-inducible kinase (Fnk) during cell-cycle progression.
Volume: 333 ( Pt 3)
Pages: 655-60
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UniProt Feature
UniProt Feature
Begin: 23
Description: Phosphoserine; by CHEK2, CK1 and PLK3
Type: modified residue
End: 23
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UniProt Feature
UniProt Feature
Begin: 53
Description: Phosphothreonine; by MAPK1, MAPK3, MAPK11, MAPK12, MAPK14 and PLK3
Type: modified residue
End: 53
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Publication
20889502 | -
First Author: Xu D
Year: 2010
Journal: J Biol Chem
Title: Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha.
Volume: 285
Issue: 50
Pages: 38944-50
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Publication
19103756 | -
First Author: López-Sánchez I
Year: 2009
Journal: Mol Cell Biol
Title: Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation.
Volume: 29
Issue: 5
Pages: 1189-201
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Allele
Plk3<em1Smoc> | MGI:7291718
Name: polo like kinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein
F6V5S5
Organism: Mus musculus/domesticus
Length: 610  
Fragment?: true
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Protein
I6L9A2
Organism: Mus musculus/domesticus
Length: 504  
Fragment?: false
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Protein
Q3U0L5
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
Q6P571
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Allele
Tg(Plk3-EGFP)FE314Gsat | MGI:4847322
Name: transgene insertion FE314, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5003563 | STOCK Tg(Plk3-EGFP)FE314Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
16627997 | -
First Author: van de Weerdt BC
Year: 2006
Journal: Cell Cycle
Title: Polo-like kinases: a team in control of the division.
Volume: 5
Issue: 8
Pages: 853-64
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Publication
15640845 | -
First Author: Seeburg DP
Year: 2005
Journal: Oncogene
Title: Polo-like kinases in the nervous system.
Volume: 24
Issue: 2
Pages: 292-8
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Publication
12957816 | -
 
First Author: Dai W
Year: 2003
Journal: Front Biosci
Title: Polo-like kinases in cell cycle checkpoint control.
Volume: 8
Pages: d1128-33
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Protein Domain
IPR042703 | PLK3_STKc
Type: Domain
Description: PLK3 (polo-like kinase 3) is a serine/threonine-protein kinase involved in cell cycle regulation, response to stress and Golgi disassembly [, , ]. It regulates angiogenesis and responses to DNA damage []. Activated PLK3 mediates Chk2 phosphorylation by ATM and the resulting checkpoint activation []. PLK3 phosphorylates DNA polymerase delta and may be involved in DNA repair. It also inhibits Cdc25c, thereby regulating the onset of mitosis [, ].STKs (serine/threonine-protein kinases) catalyse the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. PLKs (polo-like kinases) play important roles in cell cycle progression and in DNA damage responses. They regulate mitotic entry, mitotic exit, and cytokinesis. In general PLKs contain an N-terminal catalytic kinase domain and a C-terminal regulatory polo box domain (PBD), which is comprised by two bipartite polo-box motifs (or polo boxes) and is involved in protein interactions. There are five mammalian PLKs (PLK1-5) from distinct genes [, , ].
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Publication
19164942 | -
First Author: Petrinac S
Year: 2009
Journal: Cell Cycle
Title: Polo-like kinase 4 phosphorylates Chk2.
Volume: 8
Issue: 2
Pages: 327-9
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Publication
15173822 | -
First Author: Barr FA
Year: 2004
Journal: Nat Rev Mol Cell Biol
Title: Polo-like kinases and the orchestration of cell division.
Volume: 5
Issue: 6
Pages: 429-40
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Publication
26786872 | -
First Author: Vaid R
Year: 2016
Journal: Protein Pept Lett
Title: Functions of Polo-Like Kinases: A Journey From Yeast To Humans.
Volume: 23
Issue: 2
Pages: 185-97
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Publication
21968988 | -
First Author: Nigg EA
Year: 2011
Journal: Nat Cell Biol
Title: The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries.
Volume: 13
Issue: 10
Pages: 1154-60
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Publication
16326102 | -
First Author: Bettencourt-Dias M
Year: 2005
Journal: Curr Biol
Title: SAK/PLK4 is required for centriole duplication and flagella development.
Volume: 15
Issue: 24
Pages: 2199-207
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Publication
16244668 | -
First Author: Habedanck R
Year: 2005
Journal: Nat Cell Biol
Title: The Polo kinase Plk4 functions in centriole duplication.
Volume: 7
Issue: 11
Pages: 1140-6
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