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Search results 101 to 200 out of 284 for Pnpla2

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7384719
Assay Type: RT-PCR
Annotation Date: 2022-11-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:7384919
Age: embryonic day 18.5
Image: 5
Specimen Label: -/-
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:7447316
Age: embryonic day 16.5
Specimen Label: E16.5 C
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920924
Stage: TS24
Assay Id: MGI:7447316
Age: embryonic day 16.5
Specimen Label: E16.5 K
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:7447316
Age: embryonic day 18.5
Specimen Label: E18.5 C
Detected: true
Specimen Num: 3
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•
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:7447316
Age: embryonic day 18.5
Specimen Label: E18.5 K
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:7447316
Age: postnatal day 0
Specimen Label: P0 C
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:7447316
Age: postnatal day 0
Specimen Label: P0 K
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:7447316
Age: postnatal day 2
Specimen Label: P2 C
Detected: true
Specimen Num: 7
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:7447316
Age: postnatal day 2
Specimen Label: P2 K
Detected: true
Specimen Num: 8
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920928
Stage: TS28
Assay Id: MGI:7447316
Age: postnatal day 5
Specimen Label: P5 C
Detected: true
Specimen Num: 9
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•
GXD Expression
GXD Expression
     
Probe: MGI:7447254
Assay Type: Western blot
Annotation Date: 2023-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920928
Stage: TS28
Assay Id: MGI:7447316
Age: postnatal day 5
Specimen Label: P5 K
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
   
Probe: MGI:7716904
Assay Type: RT-PCR
Annotation Date: 2024-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:7716913
Age: embryonic day 18.5
Image: 1
Specimen Label: E18.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:7716904
Assay Type: RT-PCR
Annotation Date: 2024-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7716913
Age: postnatal day 5
Image: 1
Specimen Label: P5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:7716904
Assay Type: RT-PCR
Annotation Date: 2024-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7716913
Age: postnatal day 14
Image: 1
Specimen Label: P14
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:7716904
Assay Type: RT-PCR
Annotation Date: 2024-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7716913
Age: postnatal day 42
Image: 1
Specimen Label: P42
Detected: true
Specimen Num: 4
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Publication
21857651 | J:176252
First Author: Haemmerle G
Year: 2011
Journal: Nat Med
Title: ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Volume: 17
Issue: 9
Pages: 1076-85
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Publication
23413028 | J:197835
First Author: Zierler KA
Year: 2013
Journal: J Biol Chem
Title: Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.
Volume: 288
Issue: 14
Pages: 9892-904
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Publication
29232702 | J:253687
First Author: Xia B
Year: 2017
Journal: PLoS Genet
Title: Adipose tissue deficiency of hormone-sensitive lipase causes fatty liver in mice.
Volume: 13
Issue: 12
Pages: e1007110
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Publication
18572100 | J:137455
First Author: Pinent M
Year: 2008
Journal: Genomics
Title: Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice.
Volume: 92
Issue: 1
Pages: 26-32
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Publication
21464445 | J:171814
First Author: Borg ML
Year: 2011
Journal: Diabetes
Title: Pigment epithelium-derived factor regulates lipid metabolism via adipose triglyceride lipase.
Volume: 60
Issue: 5
Pages: 1458-66
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Publication
24002947 | J:330446
First Author: Jha P
Year: 2014
Journal: Hepatology
Title: Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Volume: 59
Issue: 3
Pages: 858-69
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Publication
33372146 | J:299608
 
First Author: Brejchova K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides.
Volume: 118
Issue: 2
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Publication
21680814 | J:173533
First Author: Das SK
Year: 2011
Journal: Science
Title: Adipose triglyceride lipase contributes to cancer-associated cachexia.
Volume: 333
Issue: 6039
Pages: 233-8
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Publication
26143381 | J:231197
First Author: Goeritzer M
Year: 2015
Journal: Biochim Biophys Acta
Title: Active autophagy but not lipophagy in macrophages with defective lipolysis.
Volume: 1851
Issue: 10
Pages: 1304-1316
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Publication
19491295 | J:151431
First Author: Huijsman E
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice.
Volume: 297
Issue: 2
Pages: E505-13
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Publication
31412256 | J:280101
First Author: Korbelius M
Year: 2019
Journal: Cell Rep
Title: ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes.
Volume: 28
Issue: 7
Pages: 1923-1934.e4
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Publication
18191271 | J:212673
First Author: Chung C
Year: 2008
Journal: J Hepatol
Title: Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL).
Volume: 48
Issue: 3
Pages: 471-8
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Publication
38280449 | J:345943
 
First Author: Fernandes MF
Year: 2024
Journal: Mol Metab
Title: Renal tubule-specific Atgl deletion links kidney lipid metabolism to glucagon-like peptide 1 and insulin secretion independent of renal inflammation or lipotoxicity.
Volume: 81
Pages: 101887
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Publication
23878361 | J:215855
First Author: Alsted TJ
Year: 2013
Journal: J Physiol
Title: Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle.
Volume: 591
Issue: 20
Pages: 5141-55
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Publication
23708736 | J:218658
First Author: Kienesberger PC
Year: 2013
Journal: Cardiovasc Res
Title: Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation.
Volume: 99
Issue: 3
Pages: 442-51
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Publication
33097799 | J:313501
First Author: Raje V
Year: 2020
Journal: Sci Rep
Title: Adipocyte lipolysis drives acute stress-induced insulin resistance.
Volume: 10
Issue: 1
Pages: 18166
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Publication
31185001 | J:287909
   
First Author: Zhou H
Year: 2019
Journal: JCI Insight
Title: Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
Volume: 5
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Publication
20023287 | J:160725
First Author: Radner FP
Year: 2010
Journal: J Biol Chem
Title: Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
Volume: 285
Issue: 10
Pages: 7300-11
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Publication
27248498 | J:249211
First Author: Heckmann BL
Year: 2016
Journal: PLoS One
Title: Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction.
Volume: 11
Issue: 6
Pages: e0156742
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Publication
25381252 | J:330447
First Author: Camus G
Year: 2014
Journal: J Biol Chem
Title: The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets.
Volume: 289
Issue: 52
Pages: 35770-80
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Publication
25176985 | J:216139
First Author: Brahma MK
Year: 2014
Journal: J Lipid Res
Title: Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis.
Volume: 55
Issue: 11
Pages: 2229-41
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Publication
27179362 | J:234116
First Author: Tuohetahuntila M
Year: 2016
Journal: J Lipid Res
Title: ATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cells.
Volume: 57
Issue: 7
Pages: 1162-74
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Publication
19723629 | J:155840
First Author: Kienesberger PC
Year: 2009
Journal: J Biol Chem
Title: Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.
Volume: 284
Issue: 44
Pages: 30218-29
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Publication
27396333 | J:238677
First Author: Lord CC
Year: 2016
Journal: Cell Rep
Title: Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.
Volume: 16
Issue: 4
Pages: 939-949
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Publication
24096872 | J:228991
First Author: Lettieri Barbato D
Year: 2014
Journal: Cell Death Differ
Title: Proline oxidase-adipose triglyceride lipase pathway restrains adipose cell death and tissue inflammation.
Volume: 21
Issue: 1
Pages: 113-23
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Publication
27851965 | J:241150
First Author: Sun C
Year: 2016
Journal: Cell Rep
Title: Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Suppressing Adipose Triacylglycerol Lipase Expression.
Volume: 17
Issue: 8
Pages: 2015-2027
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Publication
37172691 | J:353890
First Author: Prentice KJ
Year: 2023
Journal: J Lipid Res
Title: Sympathetic tone dictates the impact of lipolysis on FABP4 secretion.
Volume: 64
Issue: 6
Pages: 100386
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Publication
32312867 | J:293286
First Author: Liu S
Year: 2020
Journal: Diabetes
Title: Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells.
Volume: 69
Issue: 6
Pages: 1178-1192
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Publication
23297223 | J:193711
First Author: Olzmann JA
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.
Volume: 110
Issue: 4
Pages: 1345-50
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Publication
18445597 | J:138175
First Author: Schweiger M
Year: 2008
Journal: J Biol Chem
Title: The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding.
Volume: 283
Issue: 25
Pages: 17211-20
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Publication
20197052 | J:158742
First Author: Yang X
Year: 2010
Journal: Cell Metab
Title: The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase.
Volume: 11
Issue: 3
Pages: 194-205
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Publication
23850519 | J:210779
First Author: Dai Z
Year: 2013
Journal: Mol Cell Endocrinol
Title: Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity.
Volume: 377
Issue: 1-2
Pages: 123-34
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Publication
26569053 | J:250638
First Author: Zhang Y
Year: 2016
Journal: Biochim Biophys Acta
Title: Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase.
Volume: 1861
Issue: 2
Pages: 130-137
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Publication
23124680 | J:330445
First Author: Kanno Y
Year: 2013
Journal: Arthritis Rheum
Title: Alpha2-antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F(2α) synthesis through adipose triglyceride lipase/calcium-independent phospholipase A(2).
Volume: 65
Issue: 2
Pages: 492-502
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Publication
16679289 | J:129650
First Author: Lass A
Year: 2006
Journal: Cell Metab
Title: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.
Volume: 3
Issue: 5
Pages: 309-19
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Publication
17074755 | J:117712
First Author: Schweiger M
Year: 2006
Journal: J Biol Chem
Title: Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism.
Volume: 281
Issue: 52
Pages: 40236-41
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Publication
17114792 | J:118169
First Author: Miyoshi H
Year: 2007
Journal: J Biol Chem
Title: Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes.
Volume: 282
Issue: 2
Pages: 996-1002
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Publication
21148142 | J:207817
First Author: Granneman JG
Year: 2011
Journal: J Biol Chem
Title: Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase.
Volume: 286
Issue: 7
Pages: 5126-35
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Publication
22733971 | J:189193
First Author: Pagnon J
Year: 2012
Journal: Endocrinology
Title: Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase.
Volume: 153
Issue: 9
Pages: 4278-89
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Publication
29599420 | J:261511
First Author: Kotzbeck P
Year: 2018
Journal: J Lipid Res
Title: Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation.
Volume: 59
Issue: 5
Pages: 784-794
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Publication
38963761 | J:360212
First Author: Sciarretta F
Year: 2024
Journal: Cell Rep
Title: Lipid-associated macrophages reshape BAT cell identity in obesity.
Volume: 43
Issue: 7
Pages: 114447
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Publication
20842343 | J:164672
First Author: Turpin SM
Year: 2011
Journal: Diabetologia
Title: Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice.
Volume: 54
Issue: 1
Pages: 146-56
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Publication
25096179 | J:219246
First Author: MacPherson RE
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Evidence for fatty acids mediating CL 316,243-induced reductions in blood glucose in mice.
Volume: 307
Issue: 7
Pages: E563-70
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Publication
21030715 | J:184190
First Author: Lammers B
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.
Volume: 31
Issue: 1
Pages: 67-73
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Publication
23349479 | J:208574
First Author: Pulinilkunnil T
Year: 2013
Journal: Diabetes
Title: Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy.
Volume: 62
Issue: 5
Pages: 1464-77
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Publication
21641555 | J:176083
First Author: Ahmadian M
Year: 2011
Journal: Cell Metab
Title: Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype.
Volume: 13
Issue: 6
Pages: 739-48
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Publication
22225876 | J:182322
First Author: Shimizu I
Year: 2012
Journal: Cell Metab
Title: p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure.
Volume: 15
Issue: 1
Pages: 51-64
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Publication
28380348 | J:251903
First Author: Sathyanarayan A
Year: 2017
Journal: Cell Rep
Title: ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism.
Volume: 19
Issue: 1
Pages: 1-9
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Publication
28877455 | J:271997
First Author: Simcox J
Year: 2017
Journal: Cell Metab
Title: Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
Volume: 26
Issue: 3
Pages: 509-522.e6
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Publication
23220585 | J:193091
First Author: Obrowsky S
Year: 2013
Journal: J Lipid Res
Title: Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling.
Volume: 54
Issue: 2
Pages: 425-35
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Publication
28400046 | J:250745
First Author: Chen W
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Atgl gene deletion predisposes to proximal tubule damage by impairing the fatty acid metabolism.
Volume: 487
Issue: 1
Pages: 160-166
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Publication
24268737 | J:206149
First Author: Tang T
Year: 2013
Journal: Cell Metab
Title: Desnutrin/ATGL activates PPARδ to promote mitochondrial function for insulin secretion in islet β cells.
Volume: 18
Issue: 6
Pages: 883-95
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Publication
32029223 | J:329617
 
First Author: Paolella LM
Year: 2020
Journal: Mol Metab
Title: mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia.
Volume: 32
Pages: 136-147
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Publication
19297333 | J:149738
First Author: Chakrabarti P
Year: 2009
Journal: J Biol Chem
Title: FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes.
Volume: 284
Issue: 20
Pages: 13296-300
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Publication
22039468 | J:179747
First Author: Cornaciu I
Year: 2011
Journal: PLoS One
Title: The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively.
Volume: 6
Issue: 10
Pages: e26349
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Publication
24440819 | J:210848
First Author: Nagy HM
Year: 2014
Journal: Biochim Biophys Acta
Title: Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.
Volume: 1841
Issue: 4
Pages: 588-94
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Publication
25422441 | J:216801
First Author: Mullins GR
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes.
Volume: 111
Issue: 49
Pages: 17450-5
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Publication
23886955 | J:210766
First Author: Inoue T
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Downregulation of adipose triglyceride lipase in the heart aggravates diabetic cardiomyopathy in db/db mice.
Volume: 438
Issue: 1
Pages: 224-9
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Publication
27759039 | J:330437
 
First Author: Chen G
Year: 2016
Journal: Sci Rep
Title: LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL).
Volume: 6
Pages: 35531
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Publication
31917686 | J:301125
First Author: de Oliveira C
Year: 2020
Journal: J Clin Invest
Title: Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation.
Volume: 130
Issue: 4
Pages: 1931-1947
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Publication
22383686 | J:184915
First Author: Marcelin G
Year: 2012
Journal: J Lipid Res
Title: Genetic control of ATGL-mediated lipolysis modulates adipose triglyceride stores in leptin-deficient mice.
Volume: 53
Issue: 5
Pages: 964-72
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Publication
28988821 | J:256765
First Author: Schreiber R
Year: 2017
Journal: Cell Metab
Title: Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.
Volume: 26
Issue: 5
Pages: 753-763.e7
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Publication
17245390 | J:151294
First Author: Walker CG
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