|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 1092 for Ppargc1a

<< First    < Previous  |  Next >    Last >>
0.039s

Categories

Hits by Category

Hits by Strain

Type Details Score
Publication
30829673 | J:294820
First Author: Miao J
Year: 2020
Journal: Anesth Analg
Title: Proliferator-Activated Receptor-Gamma Coactivator-1α Haploinsufficiency Promotes Pain Chronification After Burn Injury.
Volume: 130
Issue: 1
Pages: 240-247
•
•
•
•
•
Publication
20720174 | J:165597
First Author: Kiilerich K
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: PGC-1alpha increases PDH content but does not change acute PDH regulation in mouse skeletal muscle.
Volume: 299
Issue: 5
Pages: R1350-9
•
•
•
•
•
Publication
17932564 | J:127403
First Author: Handschin C
Year: 2007
Journal: J Clin Invest
Title: Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.
Volume: 117
Issue: 11
Pages: 3463-74
•
•
•
•
•
Publication
26303948 | J:224824
First Author: Zhang H
Year: 2015
Journal: EMBO Rep
Title: MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network.
Volume: 16
Issue: 10
Pages: 1378-93
•
•
•
•
•
Publication
23994519 | J:210202
First Author: Ringholm S
Year: 2013
Journal: Exp Gerontol
Title: Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α.
Volume: 48
Issue: 11
Pages: 1311-8
•
•
•
•
•
Publication
29067788 | J:256432
 
First Author: Gill JF
Year: 2018
Journal: Aging Cell
Title: PGC-1α affects aging-related changes in muscle and motor function by modulating specific exercise-mediated changes in old mice.
Volume: 17
Issue: 1
•
•
•
•
•
Publication
16775082 | J:111072
First Author: Arany Z
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha.
Volume: 103
Issue: 26
Pages: 10086-91
•
•
•
•
•
Publication
21914785 | J:177378
First Author: Bhalla K
Year: 2011
Journal: Cancer Res
Title: PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis.
Volume: 71
Issue: 21
Pages: 6888-98
•
•
•
•
•
Publication
31235694 | J:278513
First Author: Agudelo LZ
Year: 2019
Journal: Nat Commun
Title: Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance.
Volume: 10
Issue: 1
Pages: 2767
•
•
•
•
•
Publication
25259918 | J:213551
First Author: Agudelo LZ
Year: 2014
Journal: Cell
Title: Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.
Volume: 159
Issue: 1
Pages: 33-45
•
•
•
•
•
Publication
21832205 | J:178809
First Author: Haase TN
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Role of PGC-1α in exercise and fasting-induced adaptations in mouse liver.
Volume: 301
Issue: 5
Pages: R1501-9
•
•
•
•
•
Publication
22087236 | J:180985
First Author: Fabregat-Andrés Ó
Year: 2011
Journal: PLoS One
Title: Induction of PGC-1α expression can be detected in blood samples of patients with ST-segment elevation acute myocardial infarction.
Volume: 6
Issue: 11
Pages: e26913
•
•
•
•
•
Publication
24769433 | J:210606
 
First Author: Dougherty SE
Year: 2014
Journal: Neuroscience
Title: Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex.
Volume: 271
Pages: 137-48
•
•
•
•
•
Publication
24253037 | J:207184
First Author: Cherry AD
Year: 2014
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor γ co-activator 1-α as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis.
Volume: 289
Issue: 1
Pages: 41-52
•
•
•
•
•
Publication
22308395 | J:182618
First Author: Finley LW
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.
Volume: 109
Issue: 8
Pages: 2931-6
•
•
•
•
•
Publication
29049322 | J:246114
First Author: Brandt N
Year: 2017
Journal: PLoS One
Title: PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle.
Volume: 12
Issue: 10
Pages: e0185993
•
•
•
•
•
Publication
26849960 | J:239261
First Author: Svensson K
Year: 2016
Journal: FASEB J
Title: Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice.
Volume: 30
Issue: 5
Pages: 1976-86
•
•
•
•
•
Publication
23141926 | J:192235
First Author: Saint-Geniez M
Year: 2013
Journal: Am J Pathol
Title: PGC-1α regulates normal and pathological angiogenesis in the retina.
Volume: 182
Issue: 1
Pages: 255-65
•
•
•
•
•
Publication
29438738 | J:268319
 
First Author: Guo X
Year: 2018
Journal: Neurobiol Dis
Title: The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury.
Volume: 113
Pages: 59-69
•
•
•
•
•
Publication
28819135 | J:256566
First Author: Jesse S
Year: 2017
Journal: Sci Rep
Title: Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington's disease.
Volume: 7
Issue: 1
Pages: 8513
•
•
•
•
•
Publication
20947495 | J:167589
First Author: Ma D
Year: 2010
Journal: J Biol Chem
Title: Neuronal inactivation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) protects mice from diet-induced obesity and leads to degenerative lesions.
Volume: 285
Issue: 50
Pages: 39087-95
•
•
•
•
•
Publication
19439529 | J:151162
First Author: Adhihetty PJ
Year: 2009
Journal: Am J Physiol Cell Physiol
Title: The role of PGC-1alpha on mitochondrial function and apoptotic susceptibility in muscle.
Volume: 297
Issue: 1
Pages: C217-25
•
•
•
•
•
Publication
16054070 | J:129842
First Author: Arany Z
Year: 2005
Journal: Cell Metab
Title: Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.
Volume: 1
Issue: 4
Pages: 259-71
•
•
•
•
•
Publication
25673772 | J:224008
First Author: Vainshtein A
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle.
Volume: 308
Issue: 9
Pages: C710-9
•
•
•
•
•
Publication
17055439 | J:144665
First Author: St-Pierre J
Year: 2006
Journal: Cell
Title: Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators.
Volume: 127
Issue: 2
Pages: 397-408
•
•
•
•
•
Publication
23916840 | J:210207
First Author: Olesen J
Year: 2013
Journal: Exp Gerontol
Title: Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation.
Volume: 48
Issue: 11
Pages: 1274-84
•
•
•
•
•
Publication
21730149 | J:174362
First Author: Selesniemi K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies.
Volume: 108
Issue: 30
Pages: 12319-24
•
•
•
•
•
Publication
31914684 | J:299661
First Author: Fierro-Fernández M
Year: 2020
Journal: FASEB J
Title: MiR-9-5p protects from kidney fibrosis by metabolic reprogramming.
Volume: 34
Issue: 1
Pages: 410-431
•
•
•
•
•
Publication
20085804 | J:164151
First Author: Leick L
Year: 2010
Journal: Exp Gerontol
Title: PGC-1alpha is required for training-induced prevention of age-associated decline in mitochondrial enzymes in mouse skeletal muscle.
Volume: 45
Issue: 5
Pages: 336-42
•
•
•
•
•
Publication
35842011 | J:328008
     
First Author: Bhattacharya D
Year: 2022
Journal: Neurosci Res
Title: Bicuculline restores frequency-dependent hippocampal I/E ratio and circuit function in PGC-1ɑ null mice.
•
•
•
•
•
Publication
18073319 | J:133426
First Author: Leick L
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle.
Volume: 294
Issue: 2
Pages: E463-74
•
•
•
•
•
Publication
20505089 | J:160823
First Author: Lucas EK
Year: 2010
Journal: J Neurosci
Title: Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha.
Volume: 30
Issue: 21
Pages: 7227-35
•
•
•
•
•
Publication
15760270 | J:96306
First Author: Leone TC
Year: 2005
Journal: PLoS Biol
Title: PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
Volume: 3
Issue: 4
Pages: e101
•
•
•
•
•
Publication
16670093 | J:114882
First Author: Burgess SC
Year: 2006
Journal: J Biol Chem
Title: Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.
Volume: 281
Issue: 28
Pages: 19000-8
•
•
•
•
•
Publication
24423644 | J:211609
 
First Author: Choi J
Year: 2014
Journal: Neurobiol Dis
Title: PGC-1α regulation of mitochondrial degeneration in experimental diabetic neuropathy.
Volume: 64
Pages: 118-30
•
•
•
•
•
Publication
27454177 | J:249151
First Author: Kim J
Year: 2016
Journal: PLoS One
Title: Regulation of Brown and White Adipocyte Transcriptome by the Transcriptional Coactivator NT-PGC-1α.
Volume: 11
Issue: 7
Pages: e0159990
•
•
•
•
•
Publication
32439544 | J:298664
 
First Author: Sun Z
Year: 2020
Journal: Neuroscience
Title: Characterization of Age-dependent Behavior Deficits in the PGC-1α Knockout Mouse, in Relevance to the Parkinson's Disease Model.
Volume: 440
Pages: 39-47
•
•
•
•
•
Publication
30210314 | J:278414
 
First Author: Szalardy L
Year: 2018
Journal: Front Behav Neurosci
Title: Non-motor Behavioral Alterations of PGC-1α-Deficient Mice - A Peculiar Phenotype With Slight Male Preponderance and No Apparent Progression.
Volume: 12
Pages: 180
•
•
•
•
•
Publication
22114039 | J:180592
First Author: Kiebish MA
Year: 2012
Journal: J Lipid Res
Title: Chronic caloric restriction attenuates a loss of sulfatide content in PGC-1α-/- mouse cortex: a potential lipidomic role of PGC-1α in neurodegeneration.
Volume: 53
Issue: 2
Pages: 273-81
•
•
•
•
•
Publication
24848065 | J:230016
First Author: Jun HJ
Year: 2014
Journal: Diabetes
Title: NT-PGC-1α activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism.
Volume: 63
Issue: 11
Pages: 3615-25
•
•
•
•
•
Publication
18487436 | J:138209
First Author: Lehman JJ
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.
Volume: 295
Issue: 1
Pages: H185-96
•
•
•
•
•
Publication
26317511 | J:243019
First Author: Su X
Year: 2015
Journal: PLoS One
Title: PGC-1α Promoter Methylation in Parkinson's Disease.
Volume: 10
Issue: 8
Pages: e0134087
•
•
•
•
•
Publication
20032509 | J:157663
First Author: Geng T
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle.
Volume: 298
Issue: 3
Pages: C572-9
•
•
•
•
•
Publication
17702743 | J:126742
First Author: Handschin C
Year: 2007
Journal: J Biol Chem
Title: Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals.
Volume: 282
Issue: 41
Pages: 30014-21
•
•
•
•
•
Publication
31290266 | J:297012
First Author: Gill JF
Year: 2019
Journal: Aging Cell
Title: Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.
Volume: 18
Issue: 5
Pages: e12993
•
•
•
•
•
Publication
28223292 | J:244935
First Author: Schnyder S
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Muscle PGC-1α is required for long-term systemic and local adaptations to a ketogenic diet in mice.
Volume: 312
Issue: 5
Pages: E437-E446
•
•
•
•
•
Publication
37639610 | J:341752
First Author: de Smalen LM
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impaired age-associated mitochondrial translation is mitigated by exercise and PGC-1α.
Volume: 120
Issue: 36
Pages: e2302360120
•
•
•
•
•
Publication
37822967 | J:347996
 
First Author: Zhang WJ
Year: 2023
Journal: Front Mol Neurosci
Title: PGC-1α regulates critical period onset/closure, mediating cortical plasticity.
Volume: 16
Pages: 1149906
•
•
•
•
•
Publication
31266022 | J:294247
First Author: Wang J
Year: 2019
Journal: Neuropsychobiology
Title: Mice Lacking the Transcriptional Coactivator PGC-1α Exhibit Hyperactivity.
Volume: 78
Issue: 4
Pages: 182-188
•
•
•
•
•
Publication
22560226 | J:184777
First Author: Da Cruz S
Year: 2012
Journal: Cell Metab
Title: Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS.
Volume: 15
Issue: 5
Pages: 778-86
•
•
•
•
•
Publication
26438561 | J:227710
First Author: Senoo N
Year: 2015
Journal: J Lipid Res
Title: PGC-1α-mediated changes in phospholipid profiles of exercise-trained skeletal muscle.
Volume: 56
Issue: 12
Pages: 2286-96
•
•
•
•
•
Publication
21881206 | J:178232
First Author: Tran M
Year: 2011
Journal: J Clin Invest
Title: PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice.
Volume: 121
Issue: 10
Pages: 4003-14
•
•
•
•
•
Publication
25987562 | J:223297
First Author: Svensson K
Year: 2015
Journal: J Biol Chem
Title: Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α).
Volume: 290
Issue: 26
Pages: 16059-76
•
•
•
•
•
Publication
30798619 | J:292586
First Author: Bhat S
Year: 2019
Journal: Circ Heart Fail
Title: Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1α (Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α) Dysregulation.
Volume: 12
Issue: 3
Pages: e005529
•
•
•
•
•
Publication
26438876 | J:226014
First Author: Minsky N
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α.
Volume: 112
Issue: 42
Pages: E5669-78
•
•
•
•
•
Publication
32372536 | J:329427
First Author: Buch BT
Year: 2020
Journal: FASEB J
Title: Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner.
Volume: 34
Issue: 6
Pages: 8653-8670
•
•
•
•
•
Publication
24277823 | J:205184
First Author: Pérez-Schindler J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling.
Volume: 110
Issue: 50
Pages: 20314-9
•
•
•
•
•
Publication
22645355 | J:185521
First Author: Kleiner S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Development of insulin resistance in mice lacking PGC-1α in adipose tissues.
Volume: 109
Issue: 24
Pages: 9635-40
•
•
•
•
•
Publication
17575086 | J:126583
First Author: Dong F
Year: 2007
Journal: Diabetes
Title: Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis.
Volume: 56
Issue: 9
Pages: 2201-12
•
•
•
•
•
Publication
37681410 | J:341609
 
First Author: Fujiwara T
Year: 2023
Journal: JCI Insight
Title: PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice.
Volume: 8
Issue: 17
•
•
•
•
•
Publication
27939396 | J:249905
First Author: Chandra R
Year: 2017
Journal: Biol Psychiatry
Title: A Role for Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α in Nucleus Accumbens Neuron Subtypes in Cocaine Action.
Volume: 81
Issue: 7
Pages: 564-572
•
•
•
•
•
Publication
12181572 | J:78333
First Author: Lin J
Year: 2002
Journal: Nature
Title: Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.
Volume: 418
Issue: 6899
Pages: 797-801
•
•
•
•
•
Publication
29859976 | J:265063
 
First Author: Karlsson L
Year: 2018
Journal: Neuroscience
Title: Constitutive PGC-1α Overexpression in Skeletal Muscle Does Not Improve Morphological Outcome in Mouse Models of Brain Irradiation or Cortical Stroke.
Volume: 384
Pages: 314-328
•
•
•
•
•
Publication
31444397 | J:298345
First Author: Karlsson L
Year: 2019
Journal: Sci Rep
Title: Constitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis.
Volume: 9
Issue: 1
Pages: 12320
•
•
•
•
•
Publication
21964033 | J:179298
First Author: Austin S
Year: 2011
Journal: Free Radic Biol Med
Title: Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain.
Volume: 51
Issue: 12
Pages: 2243-8
•
•
•
•
•
Publication
21501593 | J:172051
First Author: Summermatter S
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity.
Volume: 408
Issue: 1
Pages: 180-5
•
•
•
•
•
Publication
25128574 | J:225552
First Author: Cannavino J
Year: 2014
Journal: J Physiol
Title: PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice.
Volume: 592
Issue: 20
Pages: 4575-89
•
•
•
•
•
Publication
24686533 | J:211186
 
First Author: Arnold AS
Year: 2014
Journal: Nat Commun
Title: Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α.
Volume: 5
Pages: 3569
•
•
•
•
•
Publication
23086035 | J:208612
First Author: Summermatter S
Year: 2013
Journal: Diabetes
Title: PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner.
Volume: 62
Issue: 1
Pages: 85-95
•
•
•
•
•
Publication
23763823 | J:227888
First Author: Camacho A
Year: 2013
Journal: Eur J Neurosci
Title: Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis.
Volume: 38
Issue: 5
Pages: 2672-83
•
•
•
•
•
Publication
27185595 | J:258974
 
First Author: Siddiqui A
Year: 2016
Journal: Neurobiol Dis
Title: Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha.
Volume: 93
Pages: 115-20
•
•
•
•
•
Publication
27622213 | J:234906
 
First Author: Jiang H
Year: 2016
Journal: eNeuro
Title: Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.
Volume: 3
Issue: 4
•
•
•
•
•
Publication
33446719 | J:300441
First Author: Kim J
Year: 2021
Journal: Sci Rep
Title: NT-PGC-1α deficiency attenuates high-fat diet-induced obesity by modulating food intake, fecal fat excretion and intestinal fat absorption.
Volume: 11
Issue: 1
Pages: 1323
•
•
•
•
•
Publication
22174785 | J:182259
First Author: Tadaishi M
Year: 2011
Journal: PLoS One
Title: Skeletal muscle-specific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake.
Volume: 6
Issue: 12
Pages: e28290
•
•
•
•
•
Publication
24833782 | J:277084
First Author: Kano Y
Year: 2014
Journal: J Appl Physiol (1985)
Title: The effects of PGC-1α on control of microvascular P(O2) kinetics following onset of muscle contractions.
Volume: 117
Issue: 2
Pages: 163-70
•
•
•
•
•
Publication
20086200 | J:170051
First Author: Aoi W
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: The microRNA miR-696 regulates PGC-1{alpha} in mouse skeletal muscle in response to physical activity.
Volume: 298
Issue: 4
Pages: E799-806
•
•
•
•
•
Publication
16511594 | J:106493
First Author: Finck BN
Year: 2006
Journal: J Clin Invest
Title: PGC-1 coactivators: inducible regulators of energy metabolism in health and disease.
Volume: 116
Issue: 3
Pages: 615-22
•
•
•
•
•
Publication
17003473 | J:113374
First Author: Miura S
Year: 2006
Journal: Am J Pathol
Title: Overexpression of peroxisome proliferator-activated receptor gamma co-activator-1alpha leads to muscle atrophy with depletion of ATP.
Volume: 169
Issue: 4
Pages: 1129-39
•
•
•
•
•
Publication
17053067 | J:115257
First Author: Sandri M
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription.
Volume: 103
Issue: 44
Pages: 16260-5
•
•
•
•
•
Publication
19208857 | J:148210
First Author: Liang H
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity.
Volume: 296
Issue: 4
Pages: E945-54
•
•
•
•
•
Publication
19773550 | J:156327
First Author: Zhang Y
Year: 2009
Journal: J Biol Chem
Title: Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha.
Volume: 284
Issue: 47
Pages: 32813-26
•
•
•
•
•
Publication
20538883 | J:163190
First Author: Ogasawara E
Year: 2010
Journal: Hum Mol Genet
Title: Lactic acidemia in the pathogenesis of mice carrying mitochondrial DNA with a deletion.
Volume: 19
Issue: 16
Pages: 3179-89
•
•
•
•
•
Publication
20529956 | J:163194
First Author: Chaturvedi RK
Year: 2010
Journal: Hum Mol Genet
Title: Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation.
Volume: 19
Issue: 16
Pages: 3190-205
•
•
•
•
•
Publication
21081705 | J:172323
First Author: Uguccioni G
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: The importance of PGC-1α in contractile activity-induced mitochondrial adaptations.
Volume: 300
Issue: 2
Pages: E361-71
•
•
•
•
•
Publication
21464822 | J:173102
First Author: Aharoni-Simon M
Year: 2011
Journal: Lab Invest
Title: Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice.
Volume: 91
Issue: 7
Pages: 1018-28
•
•
•
•
•
Publication
21646374 | J:173373
First Author: Lustig Y
Year: 2011
Journal: Genes Dev
Title: Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase.
Volume: 25
Issue: 12
Pages: 1232-44
•
•
•
•
•
Publication
22246294 | J:181883
First Author: Ciron C
Year: 2012
Journal: Hum Mol Genet
Title: Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.
Volume: 21
Issue: 8
Pages: 1861-76
•
•
•
•
•
Publication
22848618 | J:189695
First Author: Rowe GC
Year: 2012
Journal: PLoS One
Title: PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle.
Volume: 7
Issue: 7
Pages: e41817
•
•
•
•
•
Publication
23175776 | J:192446
First Author: Koves TR
Year: 2013
Journal: J Lipid Res
Title: PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans.
Volume: 54
Issue: 2
Pages: 522-34
•
•
•
•
•
Publication
22648295 | J:198172
First Author: Yuan Y
Year: 2012
Journal: Kidney Int
Title: Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury.
Volume: 82
Issue: 7
Pages: 771-89
•
•
•
•
•
Publication
23212379 | J:205615
 
First Author: Cheng A
Year: 2012
Journal: Nat Commun
Title: Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines.
Volume: 3
Pages: 1250
•
•
•
•
•
Publication
24808537 | J:211042
First Author: Zhu C
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Dysfunction of the PGC-1α-mitochondria axis confers adriamycin-induced podocyte injury.
Volume: 306
Issue: 12
Pages: F1410-7
•
•
•
•
•
Publication
25241037 | J:217707
First Author: LeBleu VS
Year: 2014
Journal: Nat Cell Biol
Title: PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Volume: 16
Issue: 10
Pages: 992-1003, 1-15
•
•
•
•
•
Publication
26114427 | J:233790
First Author: Hatazawa Y
Year: 2015
Journal: PLoS One
Title: Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α.
Volume: 10
Issue: 6
Pages: e0129084
•
•
•
•
•
Publication
25422105 | J:246555
First Author: Wong KE
Year: 2015
Journal: Diabetes
Title: Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction.
Volume: 64
Issue: 5
Pages: 1532-43
•
•
•
•
•
Publication
29315328 | J:258379
First Author: Hatazawa Y
Year: 2018
Journal: PLoS One
Title: PGC-1α regulates alanine metabolism in muscle cells.
Volume: 13
Issue: 1
Pages: e0190904
•
•
•
•
•
Publication
26976621 | J:252577
First Author: Li Z
Year: 2016
Journal: Cardiovasc Res
Title: miR-199-sponge transgenic mice develop physiological cardiac hypertrophy.
Volume: 110
Issue: 2
Pages: 258-67
•
•
•
•
•
Publication
25361084 | J:259875
First Author: Rog-Zielinska EA
Year: 2015
Journal: Cell Death Differ
Title: Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α.
Volume: 22
Issue: 7
Pages: 1106-16
•
•
•
•
•
Publication
31265325 | J:283683
First Author: Halling JF
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training.
Volume: 317
Issue: 3
Pages: E513-E525
•
•
•
•
•
Publication
30982966 | J:279370
First Author: Fontecha-Barriuso M
Year: 2019
Journal: J Pathol
Title: PGC-1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI.
Volume: 249
Issue: 1
Pages: 65-78
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom