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Search results 101 to 185 out of 185 for Ppp1r15a

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7616339
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616339
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616339
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:7615280
Assay Type: Western blot
Annotation Date: 2024-03-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3679328
Stage: TS28
Assay Id: MGI:7616339
Age: postnatal week 8
Specimen Label: 8 weeks
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:7704053
Assay Type: RT-PCR
Annotation Date: 2024-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7704219
Age: embryonic day 18.0
Specimen Label: f/f
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7704053
Assay Type: RT-PCR
Annotation Date: 2024-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7704219
Age: embryonic day 18.0
Specimen Label: cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5304186
Assay Type: RNA in situ
Annotation Date: 2012-01-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1738220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5304187
Age: embryonic day 12.5
Specimen Label: 1b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5304186
Assay Type: RNA in situ
Annotation Date: 2012-01-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1672820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5304187
Age: embryonic day 12.5
Specimen Label: 1b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5304186
Assay Type: RNA in situ
Annotation Date: 2012-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Ubiquitous
Stage: TS20
Assay Id: MGI:5304187
Age: embryonic day 12.5
Specimen Label: 1b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5304186
Assay Type: RNA in situ
Annotation Date: 2012-01-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1718520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5304187
Age: embryonic day 12.5
Specimen Label: 1b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5304186
Assay Type: RNA in situ
Annotation Date: 2012-01-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5304187
Age: embryonic day 12.5
Specimen Label: 1b
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5304186
Assay Type: RNA in situ
Annotation Date: 2012-01-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5304187
Age: embryonic day 12.5
Specimen Label: 1b
Detected: true
Specimen Num: 1
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Publication
31837419 | J:301171
 
First Author: Ghadge GD
Year: 2020
Journal: Neurobiol Dis
Title: Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS.
Volume: 136
Pages: 104702
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Publication
27161320 | J:236183
First Author: Reid DW
Year: 2016
Journal: Mol Cell Biol
Title: Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response.
Volume: 36
Issue: 13
Pages: 1868-80
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Publication
25774599 | J:336380
   
First Author: Chambers JE
Year: 2015
Journal: Elife
Title: Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation.
Volume: 4
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Publication
20625881 | J:163850
First Author: Tanaka C
Year: 2010
Journal: Transgenic Res
Title: GADD34 suppresses wound healing by upregulating expression of myosin IIA.
Volume: 19
Issue: 4
Pages: 637-45
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Publication
27129771 | J:235016
First Author: Young SK
Year: 2016
Journal: J Biol Chem
Title: Nuclear Matrix Protein 4 Is a Novel Regulator of Ribosome Biogenesis and Controls the Unfolded Protein Response via Repression of Gadd34 Expression.
Volume: 291
Issue: 26
Pages: 13780-8
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Publication
18818381 | J:143347
First Author: Lin W
Year: 2008
Journal: Am J Pathol
Title: Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma.
Volume: 173
Issue: 5
Pages: 1508-17
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Publication
28984870 | J:274045
First Author: Lee IC
Year: 2018
Journal: Cell Death Differ
Title: Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function.
Volume: 25
Issue: 2
Pages: 255-267
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Publication
21439266 | J:171923
First Author: Uddin MN
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation.
Volume: 407
Issue: 4
Pages: 692-8
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Publication
24534530 | J:209902
First Author: Gu M
Year: 2014
Journal: J Immunol
Title: Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation.
Volume: 192
Issue: 6
Pages: 2846-56
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Publication
29109149 | J:256056
First Author: Goh CW
Year: 2018
Journal: J Biol Chem
Title: Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.
Volume: 293
Issue: 1
Pages: 163-176
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Publication
30923003 | J:278117
 
First Author: Dzhashiashvili Y
Year: 2019
Journal: Neurobiol Dis
Title: The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS.
Volume: 127
Pages: 527-544
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Publication
28594573 | J:265817
First Author: Khalyfa A
Year: 2017
Journal: Am J Respir Cell Mol Biol
Title: Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea.
Volume: 57
Issue: 4
Pages: 477-486
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Publication
23547100 | J:198199
First Author: D'Antonio M
Year: 2013
Journal: J Exp Med
Title: Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice.
Volume: 210
Issue: 4
Pages: 821-38
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Publication
27802424 | J:309341
First Author: Stone S
Year: 2016
Journal: Oncotarget
Title: Dual role of the integrated stress response in medulloblastoma tumorigenesis.
Volume: 7
Issue: 39
Pages: 64124-64135
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Publication
15601821 | J:95320
First Author: Marciniak SJ
Year: 2004
Journal: Genes Dev
Title: CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.
Volume: 18
Issue: 24
Pages: 3066-77
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Publication
22315398 | J:182014
First Author: Clavarino G
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells.
Volume: 109
Issue: 8
Pages: 3006-11
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Publication
23000413 | J:190089
First Author: Kimball SR
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2α phosphorylation, ATF4-dependent cascade.
Volume: 427
Issue: 3
Pages: 485-9
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Publication
31138784 | J:279812
First Author: Starr CR
Year: 2019
Journal: Cell Death Dis
Title: Delineating the role of eIF2α in retinal degeneration.
Volume: 10
Issue: 6
Pages: 409
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Publication
14635196 | J:229374
First Author: Yagi A
Year: 2003
Journal: J Cell Biochem
Title: GADD34 induces p53 phosphorylation and p21/WAF1 transcription.
Volume: 90
Issue: 6
Pages: 1242-9
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Publication
22215619 | J:183720
First Author: Majumder M
Year: 2012
Journal: Mol Cell Biol
Title: A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation.
Volume: 32
Issue: 5
Pages: 992-1003
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Publication
22959274 | J:191802
First Author: Suraweera A
Year: 2012
Journal: Mol Cell
Title: Failure of amino acid homeostasis causes cell death following proteasome inhibition.
Volume: 48
Issue: 2
Pages: 242-53
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Publication
16835242 | J:217282
First Author: Latreille M
Year: 2006
Journal: J Biol Chem
Title: Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress.
Volume: 281
Issue: 36
Pages: 26633-44
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Publication
24089213 | J:206084
First Author: Adolph TE
Year: 2013
Journal: Nature
Title: Paneth cells as a site of origin for intestinal inflammation.
Volume: 503
Issue: 7475
Pages: 272-6
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Publication
10921903 | J:63869
First Author: Weiss RS
Year: 2000
Journal: Genes Dev
Title: Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress.
Volume: 14
Issue: 15
Pages: 1886-98
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Publication
25695629 | J:221794
 
First Author: Wu H
Year: 2015
Journal: Nat Commun
Title: Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.
Volume: 6
Pages: 6239
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Publication
28100675 | J:240737
First Author: Dalet A
Year: 2017
Journal: EMBO J
Title: Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Volume: 36
Issue: 6
Pages: 761-782
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Publication
21795745 | J:177067
First Author: Zhang B
Year: 2011
Journal: Blood
Title: Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.
Volume: 118
Issue: 12
Pages: 3384-91
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Publication
22154935 | J:180513
First Author: Posey KL
Year: 2012
Journal: Am J Pathol
Title: Chop (Ddit3) is essential for D469del-COMP retention and cell death in chondrocytes in an inducible transgenic mouse model of pseudoachondroplasia.
Volume: 180
Issue: 2
Pages: 727-37
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Publication
22745161 | J:186391
First Author: Tao J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: SEC23B is required for the maintenance of murine professional secretory tissues.
Volume: 109
Issue: 29
Pages: E2001-9
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Publication
38266827 | J:345131
 
First Author: Schraps N
Year: 2024
Journal: Free Radic Biol Med
Title: Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction.
Volume: 213
Pages: 248-265
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Publication
30635284 | J:272566
 
First Author: Yang R
Year: 2019
Journal: Development
Title: CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.
Volume: 146
Issue: 2
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Publication
22925884 | J:187697
First Author: Sasaki M
Year: 2012
Journal: Genes Dev
Title: D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.
Volume: 26
Issue: 18
Pages: 2038-49
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Publication
26383973 | J:239805
First Author: Grigaravicius P
Year: 2016
Journal: Cell Death Differ
Title: Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.
Volume: 23
Issue: 3
Pages: 454-68
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Publication
29939162 | J:265679
First Author: Wang B
Year: 2018
Journal: J Clin Invest
Title: The COPII cargo adapter SEC24C is essential for neuronal homeostasis.
Volume: 128
Issue: 8
Pages: 3319-3332
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Publication
27416896 | J:240829
 
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
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Publication
26494538 | J:237614
 
First Author: Zhu M
Year: 2015
Journal: Sci Rep
Title: Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice.
Volume: 5
Pages: 15471
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Publication
18776938 | J:141141
First Author: Song B
Year: 2008
Journal: J Clin Invest
Title: Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.
Volume: 118
Issue: 10
Pages: 3378-89
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Publication
26816051 | J:250104
First Author: Flodby P
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development.
Volume: 55
Issue: 1
Pages: 135-49
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Publication
39747033 | J:360776
First Author: Di Michele M
Year: 2025
Journal: Nat Commun
Title: E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development.
Volume: 16
Issue: 1
Pages: 67
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Publication
36841836 | J:333724
First Author: Park EJ
Year: 2023
Journal: Nat Commun
Title: Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation.
Volume: 14
Issue: 1
Pages: 1097
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Publication
- | J:90559
     
First Author: The Mammalian Genetics Unit at Harwell
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Ppp1r15a<em1Hato> | MGI:7339015
 
Name: protein phosphatase 1, regulatory subunit 15A; endonuclease-mediated mutation 1, Takashi Hato
Allele Type: Endonuclease-mediated
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Allele
Ppp1r15a<em1Smoc> | MGI:7291776
Name: protein phosphatase 1, regulatory subunit 15A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6476070 | C57BL/6JSmoc-Ppp1r15a<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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