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Search results 101 to 108 out of 108 for Prex2

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Type

Details

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Allele

Prex2<em2Smoc> | MGI:7291798

Name:	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

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Strain

MGI:6771077 | C57BL/6JSmoc-Prex2<em2Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Allele

Prex2<em1Smoc> | MGI:7291797

Name:	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Conditional ready, No functional change

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Strain

MGI:6771076 | C57BL/6JSmoc-Prex2<em1Smoc>/Smoc

Attribute String:

coisogenic, endonuclease-mediated mutation, mutant strain

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Publication

15304343 | -

First Author:	Donald S
Year:	2004
Journal:	FEBS Lett
Title:	P-Rex2, a new guanine-nucleotide exchange factor for Rac.
Volume:	572
Issue:	1-3
Pages:	172-6

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Protein Domain

IPR037367 | Rex2_DEP_1

Type:	Domain
Description:	PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein []. It contains an N-terminal RhoGEF domain, two DEP and PDZ domains.This entry represents the first DEP domain of PREX2.

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Protein

Q3LAC4

Organism:	Mus musculus/domesticus
Length:	1598
Fragment?:	false

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