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Search results 101 to 200 out of 388 for Psen2

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Type Details Score
Publication
9203550 | J:40990
First Author: Blanchard V
Year: 1997
Journal: Brain Res
Title: Immunohistochemical analysis of presenilin 2 expression in the mouse brain: distribution pattern and co-localization with presenilin 1 protein.
Volume: 758
Issue: 1-2
Pages: 209-17
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Publication
9353287 | J:43976
First Author: Vito P
Year: 1997
Journal: J Biol Chem
Title: Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage.
Volume: 272
Issue: 45
Pages: 28315-20
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Publication
10846187 | J:64511
First Author: Sawamura N
Year: 2000
Journal: J Biol Chem
Title: Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin.
Volume: 275
Issue: 36
Pages: 27901-8
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Publication
9648880 | J:48145
First Author: Oyama F
Year: 1998
Journal: J Neurochem
Title: Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.
Volume: 71
Issue: 1
Pages: 313-22
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Publication
16394273 | J:104556
First Author: Lee SY
Year: 2006
Journal: FASEB J
Title: PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release.
Volume: 20
Issue: 1
Pages: 151-3
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Publication
20974250 | J:167488
First Author: Lee YJ
Year: 2011
Journal: Free Radic Biol Med
Title: 4-O-Methylhonokiol attenuates memory impairment in presenilin 2 mutant mice through reduction of oxidative damage and inactivation of astrocytes and the ERK pathway.
Volume: 50
Issue: 1
Pages: 66-77
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Publication
26593275 | J:318324
 
First Author: Hwang CJ
Year: 2016
Journal: Brain Behav Immun
Title: Acceleration of amyloidogenesis and memory impairment by estrogen deficiency through NF-κB dependent beta-secretase activation in presenilin 2 mutant mice.
Volume: 53
Pages: 113-122
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GXD Expression
GXD Expression
   
Probe: MGI:2675169
Assay Type: RT-PCR
Annotation Date: 2003-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:2675230
Age: embryonic day 14.5
Image: 1
Specimen Label: Primary tissue, +RT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6444374
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445576
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6444374
Assay Type: RT-PCR
Annotation Date: 2020-07-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6445576
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944880
Age: embryonic day 11.5
Image: g00314 E11.5
Specimen Label: g00314 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:1530345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827468
Age: embryonic day 14.5
Image: euxassay_004270_11
Specimen Label: euxassay_004270_11
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1530345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827468
Age: embryonic day 14.5
Image: euxassay_004270_12
Specimen Label: euxassay_004270_12
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:1530345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827468
Age: embryonic day 14.5
Image: euxassay_004270_14
Specimen Label: euxassay_004270_14
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
 
Probe: MGI:1530345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827468
Age: embryonic day 14.5
Image: euxassay_004270_15
Specimen Label: euxassay_004270_15
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:1530345
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827468
Age: embryonic day 14.5
Image: euxassay_004270_16
Specimen Label: euxassay_004270_16
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944880
Age: embryonic day 11.5
Image: g00314 E11.5
Specimen Label: g00314 E11.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Note: Expression was region specific and scattered.
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944880
Age: embryonic day 11.5
Image: g00314 E11.5
Specimen Label: g00314 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Note: Expression was region specific and scattered.
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944880
Age: embryonic day 11.5
Image: g00314 E11.5
Specimen Label: g00314 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944880
Age: embryonic day 11.5
Image: g00314 E11.5
Specimen Label: g00314 E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Note: Expression was region specific and scattered.
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944880
Age: embryonic day 15.5
Image: g00314 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00314 E15.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 7
Image: g00314 P7
Note: Expression was region specific and scattered.
Specimen Label: g00314 P7
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4885873
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944880
Age: postnatal day 42
Image: g00314 Adult
Note: Expression was region specific and scattered.
Specimen Label: g00314 Adult
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10419
Specimen Label: GUDMAP:10419
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001611
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542165
Age: embryonic day 15.5
Image: GUDMAP:10454
Specimen Label: GUDMAP:10454
Detected: false
Specimen Num: 2
•
•
•
•
•
Publication
17698590 | J:126088
First Author: Laky K
Year: 2007
Journal: J Exp Med
Title: Presenilins regulate alphabeta T cell development by modulating TCR signaling.
Volume: 204
Issue: 9
Pages: 2115-29
•
•
•
•
•
Publication
19005074 | J:142399
First Author: Tamboli IY
Year: 2008
Journal: J Neurosci
Title: Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Volume: 28
Issue: 46
Pages: 12097-106
•
•
•
•
•
Publication
18297083 | J:233142
First Author: Hilton MJ
Year: 2008
Journal: Nat Med
Title: Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.
Volume: 14
Issue: 3
Pages: 306-14
•
•
•
•
•
Publication
8560270 | J:33763
First Author: Vito P
Year: 1996
Journal: Science
Title: Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3.
Volume: 271
Issue: 5248
Pages: 521-5
•
•
•
•
•
Publication
32961023 | J:326593
First Author: Bi HR
Year: 2021
Journal: CNS Neurosci Ther
Title: Neuron-specific deletion of presenilin enhancer2 causes progressive astrogliosis and age-related neurodegeneration in the cortex independent of the Notch signaling.
Volume: 27
Issue: 2
Pages: 174-185
•
•
•
•
•
Publication
30559648 | J:321022
 
First Author: Naranjo R
Year: 2018
Journal: Front Mol Neurosci
Title: Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis.
Volume: 11
Pages: 449
•
•
•
•
•
Publication
37714307 | J:341241
 
First Author: Lisgaras CP
Year: 2023
Journal: Neurobiol Dis
Title: Interictal spikes in Alzheimer's disease: Preclinical evidence for dominance of the dentate gyrus and cholinergic control by the medial septum.
Volume: 187
Pages: 106294
•
•
•
•
•
Publication
35418126 | J:325409
First Author: Nam H
Year: 2022
Journal: Nat Commun
Title: Presenilin 2 N141I mutation induces hyperactive immune response through the epigenetic repression of REV-ERBα.
Volume: 13
Issue: 1
Pages: 1972
•
•
•
•
•
Publication
19656855 | J:152904
First Author: Lee JW
Year: 2009
Journal: J Nutr
Title: Green tea (-)-epigallocatechin-3-gallate inhibits beta-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and NF-kappaB pathways in mice.
Volume: 139
Issue: 10
Pages: 1987-93
•
•
•
•
•
Publication
8940094 | J:37098
First Author: Vito P
Year: 1996
Journal: J Biol Chem
Title: Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3.
Volume: 271
Issue: 49
Pages: 31025-8
•
•
•
•
•
Publication
9450754 | J:71037
First Author: De Strooper B
Year: 1998
Journal: Nature
Title: Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
Volume: 391
Issue: 6665
Pages: 387-90
•
•
•
•
•
Publication
8755489 | J:34323
First Author: Thinakaran G
Year: 1996
Journal: Neuron
Title: Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo.
Volume: 17
Issue: 1
Pages: 181-90
•
•
•
•
•
Publication
19641596 | J:150936
First Author: Zhang C
Year: 2009
Journal: Nature
Title: Presenilins are essential for regulating neurotransmitter release.
Volume: 460
Issue: 7255
Pages: 632-6
•
•
•
•
•
Publication
22311977 | J:316671
First Author: Shilling D
Year: 2012
Journal: J Biol Chem
Title: Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.
Volume: 287
Issue: 14
Pages: 10933-44
•
•
•
•
•
Publication
12460542 | J:125448
First Author: Chan SL
Year: 2002
Journal: Neurobiol Dis
Title: Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Volume: 11
Issue: 1
Pages: 2-19
•
•
•
•
•
Publication
22723704 | J:185660
First Author: Zhang X
Year: 2012
Journal: J Neurosci
Title: A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.
Volume: 32
Issue: 25
Pages: 8633-48
•
•
•
•
•
Publication
34662541 | J:321406
 
First Author: Sánchez-Hidalgo AC
Year: 2022
Journal: Exp Neurol
Title: Selective expression of the neurexin substrate for presenilin in the adult forebrain causes deficits in associative memory and presynaptic plasticity.
Volume: 347
Pages: 113896
•
•
•
•
•
Publication
30560948 | J:272071
First Author: Dhaliwal J
Year: 2018
Journal: Sci Rep
Title: Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2.
Volume: 8
Issue: 1
Pages: 17931
•
•
•
•
•
Publication
31376499 | J:347062
 
First Author: Zhao Y
Year: 2019
Journal: Brain Behav Immun
Title: Trans-cinnamaldehyde improves neuroinflammation-mediated NMDA receptor dysfunction and memory deficits through blocking NF-κB pathway in presenilin1/2 conditional double knockout mice.
Volume: 82
Pages: 45-62
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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