Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_12 |
|
Specimen Label: |
euxassay_001898_12 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_13 |
|
Specimen Label: |
euxassay_001898_13 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_14 |
|
Specimen Label: |
euxassay_001898_14 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_15 |
|
Specimen Label: |
euxassay_001898_15 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_16 |
|
Specimen Label: |
euxassay_001898_16 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_17 |
|
Specimen Label: |
euxassay_001898_17 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_18 |
|
Specimen Label: |
euxassay_001898_18 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_19 |
|
Specimen Label: |
euxassay_001898_19 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_20 |
|
Specimen Label: |
euxassay_001898_20 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_21 |
|
Specimen Label: |
euxassay_001898_21 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1830623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_22 |
|
Specimen Label: |
euxassay_001898_22 |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7491864 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1674717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7491960 |
Age: |
embryonic day 10.5 |
Image: |
S4 |
|
Specimen Label: |
S4 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7491864 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-06-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1720917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:7491960 |
Age: |
embryonic day 10.5 |
Image: |
S4 |
|
Specimen Label: |
S4 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4354959 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Rod1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-08-31 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7522835 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615950 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679727 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3618079 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
P0 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_02 |
|
Specimen Label: |
euxassay_001898_02 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_03 |
|
Specimen Label: |
euxassay_001898_03 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_04 |
|
Specimen Label: |
euxassay_001898_04 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_05 |
|
Specimen Label: |
euxassay_001898_05 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_06 |
|
Specimen Label: |
euxassay_001898_06 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_07 |
|
Specimen Label: |
euxassay_001898_07 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_16 |
|
Specimen Label: |
euxassay_001898_16 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_17 |
|
Specimen Label: |
euxassay_001898_17 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_18 |
|
Specimen Label: |
euxassay_001898_18 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_19 |
|
Specimen Label: |
euxassay_001898_19 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:905478 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827787 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_001898_20 |
|
Specimen Label: |
euxassay_001898_20 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615950 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754027 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3618079 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
P0 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615950 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280927 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3618079 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
P0 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615950 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-28 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3618079 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
E13.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615950 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757721 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3618079 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615950 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-28 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757727 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3618079 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
P0 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hüttelmaier S |
Year: |
2001 |
Journal: |
J Cell Biol |
Title: |
Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins. |
Volume: |
155 |
Issue: |
5 |
Pages: |
775-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suckale J |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
PTBP1 is required for embryonic development before gastrulation. |
Volume: |
6 |
Issue: |
2 |
Pages: |
e16992 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng S |
Year: |
2013 |
Journal: |
Genome Res |
Title: |
A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. |
Volume: |
23 |
Issue: |
6 |
Pages: |
998-1007 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JS |
Year: |
2012 |
Journal: |
BMC Genomics |
Title: |
Transcriptional ontogeny of the developing liver. |
Volume: |
13 |
|
Pages: |
33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pavlinkova G |
Year: |
2009 |
Journal: |
BMC Genomics |
Title: |
Maternal diabetes alters transcriptional programs in the developing embryo. |
Volume: |
10 |
|
Pages: |
274 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sansom SN |
Year: |
2009 |
Journal: |
PLoS Genet |
Title: |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. |
Volume: |
5 |
Issue: |
6 |
Pages: |
e1000511 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKee AE |
Year: |
2005 |
Journal: |
BMC Dev Biol |
Title: |
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. |
Volume: |
5 |
|
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
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Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
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Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
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Title: |
MGI Sequence Curation Reference |
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Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Allele |
Name: |
polypyrimidine tract binding protein 3; targeted mutation 1, Martin Turner |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RNA recognition motif 2 (RRM2) of polypyrimidine tract-binding protein 1 (PTBP1) and related proteins. Proteins containing this domain include PTBP1/2/3 (or PTB1/2/3) and heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL) proteins. PTB can shuttle between nucleus and cytoplasm. It is a splicing repressor factor implicated in the control of alternative exon selection during mRNA processing of many different transcribed genes, including its own pre-mRNA. It is also involved in internal ribosome entry site (IRES)-mediated translation initiation. It may also be involved in the 3'-end processing, localization, and stability of several mRNAs. Two PTB homologues, PTBP2 and PTBP3, are generally expressed in mammalian tissues. PTBP2 is expressed at high levels in adult brain, muscle and testis, while PTBP3 is expressed preferentially in haematopoietic cells []. PTB and PTBP2 bind to the same RNA sequences and have similar effects on alternative splicing events. However, differential expression of PTB and PTBP2 can lead to the generation of alternatively spliced mRNAs []. During neuronal differentiation, MicroRNA miR-124 downregulates PTBP1 expression, which in turn leads to upregulation of PTBP2. Later in development, the expression of PTBP2 decreases and this leads to a second wave of alternative splicing changes characteristic of adult brain and essential for brain development []. PTBP3 may be involved in nonsense-mediated mRNA decay []. |
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RNA recognition motif 2 (RRM2) of polypyrimidine tract-binding protein 1 (PTB or hnRNP I), polypyrimidine tract-binding protein 2 (PTBP2 or nPTB), polypyrimidine tract-binding protein 3 (PTBP3 or Rod1), and similar proteins found in Metazoa.PTB can shuttle between nucleus and cytoplasm. It is a splicing repressor factor implicated in the control of alternative exon selection during mRNA processing of many different transcribed genes, including its own pre-mRNA. It is also involved in internal ribosome entry site (IRES)-mediated translation initiation. It may also be involved in the 3'-end processing, localization, and stability of several mRNAs. Two PTB homologues, PTBP2 and PTBP3, are generally expressed in mammalian tissues. PTBP2 is expressed at high levels in adult brain, muscle and testis, while PTBP3 is expressed preferentially in haematopoietic cells []. PTB and PTBP2 bind to the same RNA sequences and have similar effects on alternative splicing events. However, differential expression of PTB and PTBP2 can lead to the generation of alternatively spliced mRNAs []. During neuronal differentiation, MicroRNA miR-124 downregulates PTBP1 expression, which in turn leads to upregulation of PTBP2. Later in development, the expression of PTBP2 decreases and this leads to a second wave of alternative splicing changes characteristic of adult brain and essential for brain development []. PTBP3 may be involved in nonsense-mediated mRNA decay []. |
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Publication |
First Author: |
Brazão TF |
Year: |
2012 |
Journal: |
FEBS Lett |
Title: |
A new function of ROD1 in nonsense-mediated mRNA decay. |
Volume: |
586 |
Issue: |
8 |
Pages: |
1101-10 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
489
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
528
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
457
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
356
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
 |
Fragment?: |
true |
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Publication |
First Author: |
Romanelli MG |
Year: |
2013 |
Journal: |
Int J Mol Sci |
Title: |
New insights into functional roles of the polypyrimidine tract-binding protein. |
Volume: |
14 |
Issue: |
11 |
Pages: |
22906-32 |
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Publication |
First Author: |
Joshi A |
Year: |
2014 |
Journal: |
PeerJ |
Title: |
Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB). |
Volume: |
2 |
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Pages: |
e305 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
172
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
523
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
531
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
555
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
554
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
551
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
529
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
530
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
555
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
299
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
555
 |
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
520
 |
Fragment?: |
false |
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•
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