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Search results 101 to 200 out of 269 for Ptpn1

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5287015
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5287015
Age: postnatal day 12
Specimen Label: P12
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5287015
Age: postnatal day 16
Specimen Label: P16
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286928
Stage: TS28
Assay Id: MGI:5287015
Age: postnatal day 20
Specimen Label: P20
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5286913
Assay Type: Western blot
Annotation Date: 2011-09-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:5287015
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 1
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Publication
29122767 | J:253863
First Author: Le Sommer S
Year: 2018
Journal: Cancer Res
Title: Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
Volume: 78
Issue: 1
Pages: 75-87
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Publication
22844492 | J:189720
First Author: Fuentes F
Year: 2012
Journal: PLoS One
Title: Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.
Volume: 7
Issue: 7
Pages: e41536
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Publication
17576811 | J:125012
First Author: Kuchay SM
Year: 2007
Journal: Mol Cell Biol
Title: Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets.
Volume: 27
Issue: 17
Pages: 6038-52
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Publication
31915254 | J:287982
First Author: Ricke KM
Year: 2020
Journal: J Neurosci
Title: Neuronal Protein Tyrosine Phosphatase 1B Hastens Amyloid β-Associated Alzheimer's Disease in Mice.
Volume: 40
Issue: 7
Pages: 1581-1593
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Publication
34044147 | J:307396
 
First Author: Zhang L
Year: 2021
Journal: Neurobiol Dis
Title: Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease.
Volume: 156
Pages: 105402
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Publication
26813343 | J:336948
First Author: Foronjy RF
Year: 2016
Journal: Mucosal Immunol
Title: Protein tyrosine phosphatase 1B negatively regulates S100A9-mediated lung damage during respiratory syncytial virus exacerbations.
Volume: 9
Issue: 5
Pages: 1317-29
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Publication
23937695 | J:317569
 
First Author: Bakke J
Year: 2013
Journal: Cell Commun Signal
Title: Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B.
Volume: 11
Pages: 57
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Publication
30625317 | J:335837
First Author: Balland E
Year: 2019
Journal: Cell Rep
Title: Leptin Signaling in the Arcuate Nucleus Reduces Insulin's Capacity to Suppress Hepatic Glucose Production in Obese Mice.
Volume: 26
Issue: 2
Pages: 346-355.e3
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Publication
33627831 | J:306517
First Author: Ghosh S
Year: 2021
Journal: Commun Biol
Title: βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity.
Volume: 4
Issue: 1
Pages: 248
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Publication
27323329 | J:236798
First Author: Banh RS
Year: 2016
Journal: Nat Cell Biol
Title: PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia.
Volume: 18
Issue: 7
Pages: 803-813
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Publication
26953321 | J:280721
First Author: Huby AC
Year: 2016
Journal: Hypertension
Title: Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice.
Volume: 67
Issue: 5
Pages: 1020-8
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Publication
23512805 | J:198119
First Author: Lackey DE
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.
Volume: 304
Issue: 11
Pages: E1175-87
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Publication
19797171 | J:169952
First Author: Ali MI
Year: 2009
Journal: Circ Res
Title: Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone.
Volume: 105
Issue: 10
Pages: 1013-22
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Publication
23178931 | J:194636
First Author: Panzhinskiy E
Year: 2013
Journal: Diabetologia
Title: Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes.
Volume: 56
Issue: 3
Pages: 598-607
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Publication
15369800 | J:92476
First Author: Rondinone CM
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Reduction of PTP1B induces differential expression of PI3-kinase (p85alpha) isoforms.
Volume: 323
Issue: 2
Pages: 652-9
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Publication
11970899 | J:75969
First Author: Cheng A
Year: 2002
Journal: Dev Cell
Title: Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.
Volume: 2
Issue: 4
Pages: 497-503
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Publication
24519936 | J:326410
First Author: Shi L
Year: 2014
Journal: J Biol Chem
Title: Sustained high protein-tyrosine phosphatase 1B activity in the sperm of obese males impairs the sperm acrosome reaction.
Volume: 289
Issue: 12
Pages: 8432-41
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Publication
25796170 | J:222870
First Author: Liu ZQ
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Fumosorinone, a novel PTP1B inhibitor, activates insulin signaling in insulin-resistance HepG2 cells and shows anti-diabetic effect in diabetic KKAy mice.
Volume: 285
Issue: 1
Pages: 61-70
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Publication
21849469 | J:205401
First Author: Balavenkatraman KK
Year: 2011
Journal: Mol Cancer Res
Title: Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.
Volume: 9
Issue: 10
Pages: 1377-84
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Publication
23089336 | J:190444
First Author: Nelson JF
Year: 2012
Journal: J Gerontol A Biol Sci Med Sci
Title: Probing the relationship between insulin sensitivity and longevity using genetically modified mice.
Volume: 67
Issue: 12
Pages: 1332-8
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Publication
16267035 | J:102693
First Author: Dubé N
Year: 2005
Journal: Cancer Res
Title: Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development.
Volume: 65
Issue: 21
Pages: 10088-95
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Publication
32958258 | J:304528
First Author: Yue L
Year: 2020
Journal: Biochem Biophys Res Commun
Title: PTP1B negatively regulates STAT1-independent Pseudomonas aeruginosa killing by macrophages.
Volume: 533
Issue: 3
Pages: 296-303
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Publication
29708510 | J:262733
First Author: Ubil E
Year: 2018
Journal: J Clin Invest
Title: Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response.
Volume: 128
Issue: 6
Pages: 2356-2369
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Publication
23702782 | J:214039
First Author: Arroba AI
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice.
Volume: 54
Issue: 6
Pages: 4215-25
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Publication
14693698 | J:87249
First Author: Kushner JA
Year: 2004
Journal: Diabetes
Title: Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice.
Volume: 53
Issue: 1
Pages: 61-6
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Publication
22160220 | J:311775
 
First Author: Murillo-Cuesta S
Year: 2012
Journal: Mol Med
Title: Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function.
Volume: 18
Pages: 260-9
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Publication
20876718 | J:169330
First Author: Briancon N
Year: 2010
Journal: Diabetes
Title: Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance.
Volume: 59
Issue: 12
Pages: 3074-84
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Publication
23139353 | J:208606
First Author: Yu IC
Year: 2013
Journal: Diabetes
Title: Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-κB-mediated PTP1B expression.
Volume: 62
Issue: 2
Pages: 411-23
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Publication
17664276 | J:126526
First Author: Ruffolo SC
Year: 2007
Journal: J Biol Chem
Title: Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
Volume: 282
Issue: 42
Pages: 30423-33
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Publication
25018087 | J:234223
First Author: Kandadi MR
Year: 2015
Journal: Biochim Biophys Acta
Title: Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: Role of AMPK-dependent autophagy.
Volume: 1852
Issue: 2
Pages: 299-309
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Publication
24803538 | J:259718
First Author: Pike KA
Year: 2014
Journal: Sci Signal
Title: Protein tyrosine phosphatase 1B is a regulator of the interleukin-10-induced transcriptional program in macrophages.
Volume: 7
Issue: 324
Pages: ra43
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Publication
23135963 | J:194693
First Author: Bourdeau A
Year: 2013
Journal: Stem Cells
Title: Inhibition of T cell protein tyrosine phosphatase enhances interleukin-18-dependent hematopoietic stem cell expansion.
Volume: 31
Issue: 2
Pages: 293-304
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Publication
25974252 | J:235320
First Author: Herren DJ
Year: 2015
Journal: PLoS One
Title: Deletion of Protein Tyrosine Phosphatase 1B (PTP1B) Enhances Endothelial Cyclooxygenase 2 Expression and Protects Mice from Type 1 Diabetes-Induced Endothelial Dysfunction.
Volume: 10
Issue: 5
Pages: e0126866
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Publication
19474293 | J:150081
First Author: Heinonen KM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-gamma signaling.
Volume: 106
Issue: 23
Pages: 9368-72
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Publication
24937445 | J:219436
First Author: Pandey NR
Year: 2014
Journal: Biochem Biophys Res Commun
Title: LMO4 is required to maintain hypothalamic insulin signaling.
Volume: 450
Issue: 1
Pages: 666-72
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Publication
15031294 | J:122895
First Author: Zabolotny JM
Year: 2004
Journal: J Biol Chem
Title: Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.
Volume: 279
Issue: 23
Pages: 24844-51
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Publication
11970898 | J:75970
First Author: Zabolotny JM
Year: 2002
Journal: Dev Cell
Title: PTP1B regulates leptin signal transduction in vivo.
Volume: 2
Issue: 4
Pages: 489-95
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Publication
27288485 | J:236262
First Author: Foronjy RF
Year: 2016
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice.
Volume: 311
Issue: 1
Pages: L154-66
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Publication
23275627 | J:194934
First Author: Berdnikovs S
Year: 2013
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Endothelial cell PTP1B regulates leukocyte recruitment during allergic inflammation.
Volume: 304
Issue: 4
Pages: L240-9
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Publication
22252315 | J:183709
First Author: Zee T
Year: 2012
Journal: Mol Cell Biol
Title: T-cell protein tyrosine phosphatase regulates bone resorption and whole-body insulin sensitivity through its expression in osteoblasts.
Volume: 32
Issue: 6
Pages: 1080-8
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Publication
23832083 | J:203304
First Author: Owen C
Year: 2013
Journal: Diabetologia
Title: Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice.
Volume: 56
Issue: 10
Pages: 2286-96
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Publication
24749060 | J:208832
First Author: Tsou RC
Year: 2014
Journal: Mol Metab
Title: Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor.
Volume: 3
Issue: 3
Pages: 301-12
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Publication
37730132 | J:344074
First Author: Hsu MF
Year: 2024
Journal: Biochim Biophys Acta Mol Cell Res
Title: Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte.
Volume: 1871
Issue: 1
Pages: 119590
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Publication
29351427 | J:260258
First Author: Aberdein N
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance.
Volume: 314
Issue: 3
Pages: R478-R488
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Publication
21406615 | J:172299
First Author: De Jonghe BC
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure.
Volume: 300
Issue: 6
Pages: E1002-11
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Publication
24982127 | J:227459
First Author: Lanahan AA
Year: 2014
Journal: Circulation
Title: PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.
Volume: 130
Issue: 11
Pages: 902-9
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Publication
22802463 | J:189156
First Author: Tsou RC
Year: 2012
Journal: Endocrinology
Title: Deficiency of PTP1B in leptin receptor-expressing neurons leads to decreased body weight and adiposity in mice.
Volume: 153
Issue: 9
Pages: 4227-37
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Publication
31509751 | J:281006
First Author: Dodd GT
Year: 2019
Journal: Cell Rep
Title: Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity.
Volume: 28
Issue: 11
Pages: 2905-2922.e5
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Publication
15632081 | J:96001
First Author: Galic S
Year: 2005
Journal: Mol Cell Biol
Title: Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.
Volume: 25
Issue: 2
Pages: 819-29
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Publication
11788587 | J:75453
First Author: Murphy GA
Year: 2002
Journal: J Biol Chem
Title: Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation.
Volume: 277
Issue: 12
Pages: 9966-75
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Publication
21135139 | J:168688
First Author: Nievergall E
Year: 2010
Journal: J Cell Biol
Title: PTP1B regulates Eph receptor function and trafficking.
Volume: 191
Issue: 6
Pages: 1189-203
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Publication
21216966 | J:219081
First Author: Bettaieb A
Year: 2011
Journal: J Biol Chem
Title: Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase.
Volume: 286
Issue: 11
Pages: 9225-35
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Publication
16198645 | J:104889
First Author: Dubé N
Year: 2005
Journal: Biochim Biophys Acta
Title: Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: from diabetes, obesity to cell cycle, and cancer.
Volume: 1754
Issue: 1-2
Pages: 108-17
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Publication
17908559 | J:130027
First Author: Sun C
Year: 2007
Journal: Cell Metab
Title: SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B.
Volume: 6
Issue: 4
Pages: 307-19
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Publication
17339486 | J:144272
First Author: Deem TL
Year: 2007
Journal: J Immunol
Title: VCAM-1 activation of endothelial cell protein tyrosine phosphatase 1B.
Volume: 178
Issue: 6
Pages: 3865-73
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Publication
19029027 | J:146674
First Author: Rajala RV
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity.
Volume: 50
Issue: 3
Pages: 1033-40
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Publication
20059965 | J:157870
First Author: Blanquart C
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Protein tyrosine phosphatase-1B and T-cell protein tyrosine phosphatase regulate IGF-2-induced MCF-7 cell migration.
Volume: 392
Issue: 1
Pages: 83-8
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Publication
23129613 | J:192265
First Author: Carbone CJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies.
Volume: 109
Issue: 47
Pages: 19226-31
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Publication
23590304 | J:231651
First Author: Geraghty P
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis. A key determinant of airway inflammation and alveolar destruction.
Volume: 49
Issue: 5
Pages: 721-30
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Publication
31309546 | J:295563
First Author: Wu J
Year: 2019
Journal: FEBS Lett
Title: Egr-1 transcriptionally activates protein phosphatase PTP1B to facilitate hyperinsulinemia-induced insulin resistance in the liver in type 2 diabetes.
Volume: 593
Issue: 21
Pages: 3054-3063
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Publication
22000926 | J:179621
First Author: Loh K
Year: 2011
Journal: Cell Metab
Title: Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.
Volume: 14
Issue: 5
Pages: 684-99
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Publication
33003981 | J:328940
First Author: Bruder-Nascimento T
Year: 2020
Journal: J Am Heart Assoc
Title: HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor-Dependent Increases in NADPH Oxidase 1 (Nox1), C-C Chemokine Receptor Type 5 (CCR5), and Inflammation.
Volume: 9
Issue: 19
Pages: e018074
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33293360 | J:302570
First Author: Lesnikova A
Year: 2021
Journal: J Neurosci
Title: Chondroitinase and Antidepressants Promote Plasticity by Releasing TRKB from Dephosphorylating Control of PTPσ in Parvalbumin Neurons.
Volume: 41
Issue: 5
Pages: 972-980
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Publication
25594176 | J:219581
First Author: Dodd GT
Year: 2015
Journal: Cell
Title: Leptin and insulin act on POMC neurons to promote the browning of white fat.
Volume: 160
Issue: 1-2
Pages: 88-104
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19930043 | J:162283
First Author: Pouliot P
Year: 2009
Journal: Immunology
Title: The role of protein tyrosine phosphatases in the regulation of allergic asthma: implication of TC-PTP and PTP-1B in the modulation of disease development.
Volume: 128
Issue: 4
Pages: 534-42
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Publication
20061388 | J:161083
First Author: Rajala RV
Year: 2010
Journal: J Biol Chem
Title: Enhanced retinal insulin receptor-activated neuroprotective survival signal in mice lacking the protein-tyrosine phosphatase-1B gene.
Volume: 285
Issue: 12
Pages: 8894-904
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Publication
38199575 | J:345661
First Author: Datta R
Year: 2024
Journal: J Biol Chem
Title: PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
Volume: 300
Issue: 2
Pages: 105631
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Publication
38517889 | J:348600
First Author: Schwartz L
Year: 2024
Journal: Cell Rep
Title: Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection.
Volume: 43
Issue: 4
Pages: 114007
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Publication
38336024 | J:348630
 
First Author: Ge X
Year: 2024
Journal: Brain Behav Immun
Title: Overexpression of forebrain PTP1B leads to synaptic and cognitive impairments in obesity.
Volume: 117
Pages: 456-470
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Publication
21791607 | J:175867
First Author: Basavarajappa DK
Year: 2011
Journal: Mol Cell Biol
Title: Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14.
Volume: 31
Issue: 19
Pages: 3975-87
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Publication
32094367 | J:286290
First Author: Zhang L
Year: 2020
Journal: Nat Commun
Title: Hyperactivated PTP1B phosphatase in parvalbumin neurons alters anterior cingulate inhibitory circuits and induces autism-like behaviors.
Volume: 11
Issue: 1
Pages: 1017
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Publication
24590766 | J:210736
First Author: Medgyesi D
Year: 2014
Journal: J Exp Med
Title: The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity.
Volume: 211
Issue: 3
Pages: 427-40
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Publication
22509299 | J:317568
First Author: Bettaieb A
Year: 2012
Journal: PLoS One
Title: Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.
Volume: 7
Issue: 4
Pages: e34412
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Publication
22389718 | J:198408
First Author: Owen C
Year: 2012
Journal: PLoS One
Title: Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis.
Volume: 7
Issue: 2
Pages: e32700
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Publication
8955893 | J:37951
First Author: Park KS
Year: 1996
Journal: Biochem Mol Biol Int
Title: Molecular cloning and expression of a cDNA encoding a protein tyrosine phosphatase from mouse brain.
Volume: 40
Issue: 5
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