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Search results 101 to 200 out of 420 for Rad50

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Type Details Score
Publication
26512707 | J:320151
First Author: Lavin MF
Year: 2015
Journal: Biomolecules
Title: ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor.
Volume: 5
Issue: 4
Pages: 2877-902
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Publication
21677273 | J:178657
First Author: Dmitrieva NI
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Mre11 is expressed in mammalian mitochondria where it binds to mitochondrial DNA.
Volume: 301
Issue: 3
Pages: R632-40
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Publication
9149945 | J:40314
First Author: Frazer KA
Year: 1997
Journal: Genome Res
Title: Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.
Volume: 7
Issue: 5
Pages: 495-512
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Publication
18854157 | J:147247
First Author: Buis J
Year: 2008
Journal: Cell
Title: Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.
Volume: 135
Issue: 1
Pages: 85-96
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Publication
19633670 | J:272543
First Author: Dinkelmann M
Year: 2009
Journal: Nat Struct Mol Biol
Title: Multiple functions of MRN in end-joining pathways during isotype class switching.
Volume: 16
Issue: 8
Pages: 808-13
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Publication
19667071 | J:153904
First Author: Dimitrova N
Year: 2009
Journal: Mol Cell Biol
Title: Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2.
Volume: 29
Issue: 20
Pages: 5552-63
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Publication
15965469 | J:100798
First Author: Difilippantonio S
Year: 2005
Journal: Nat Cell Biol
Title: Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.
Volume: 7
Issue: 7
Pages: 675-85
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Publication
10655497 | J:60187
First Author: Zhu Y
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Genomic interval engineering of mice identifies a novel modulator of triglyceride production.
Volume: 97
Issue: 3
Pages: 1137-42
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Publication
15734743 | J:99937
First Author: Alt JR
Year: 2005
Journal: J Biol Chem
Title: Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
Volume: 280
Issue: 19
Pages: 18771-81
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Publication
28819025 | J:245675
First Author: Spehalski E
Year: 2017
Journal: Cancer Res
Title: MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.
Volume: 77
Issue: 19
Pages: 5327-5338
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Publication
19221393 | J:146799
First Author: Helmink BA
Year: 2009
Journal: J Exp Med
Title: MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Volume: 206
Issue: 3
Pages: 669-79
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Publication
30657944 | J:319683
First Author: Mohiuddin M
Year: 2019
Journal: Nucleic Acids Res
Title: CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.
Volume: 47
Issue: 6
Pages: 2966-2980
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Publication
29709199 | J:320083
 
First Author: Syed A
Year: 2018
Journal: Annu Rev Biochem
Title: The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
Volume: 87
Pages: 263-294
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Publication
18171670 | J:319979
First Author: Chen L
Year: 2008
Journal: J Biol Chem
Title: Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
Volume: 283
Issue: 12
Pages: 7713-20
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Publication
33524014 | J:305161
First Author: Dar AA
Year: 2021
Journal: PLoS Biol
Title: The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.
Volume: 19
Issue: 2
Pages: e3001041
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Publication
15615879 | J:96841
First Author: Gong SG
Year: 2005
Journal: J Dent Res
Title: Identification of markers of the midface.
Volume: 84
Issue: 1
Pages: 69-72
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Publication
22369660 | J:320080
First Author: Wang B
Year: 2012
Journal: Cell Biosci
Title: BRCA1 tumor suppressor network: focusing on its tail.
Volume: 2
Issue: 1
Pages: 6
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Publication
10704283 | J:60872
First Author: Wenderfer SE
Year: 2000
Journal: Genomics
Title: Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.
Volume: 63
Issue: 3
Pages: 354-73
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Publication
36178098 | J:330334
 
First Author: Zhang H
Year: 2022
Journal: Development
Title: The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance.
Volume: 149
Issue: 19
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Publication
17500065 | J:123598
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
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Publication
35920200 | J:329968
First Author: Kazi S
Year: 2022
Journal: FASEB J
Title: MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.
Volume: 36
Issue: 9
Pages: e22479
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Publication
10464095 | J:57234
First Author: Lee CK
Year: 1999
Journal: Science
Title: Gene expression profile of aging and its retardation by caloric restriction.
Volume: 285
Issue: 5432
Pages: 1390-3
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Gene
475893 | RINT1
Type: gene
Organism: dog, domestic
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Gene
743241 | RINT1
Type: gene
Organism: chimpanzee
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Gene
296750 | Rint1
Type: gene
Organism: rat
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Gene
510686 | RINT1
Type: gene
Organism: cattle
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Gene
427848 | RINT1
Type: gene
Organism: chicken
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Gene
562894 | rint1
Type: gene
Organism: zebrafish
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Gene
698414 | RINT1
Type: gene
Organism: macaque, rhesus
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Gene
100379743 | rint1
Type: gene
Organism: frog, western clawed
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UniProt Feature
UniProt Feature
Begin: 1
Description: DNA repair protein RAD50
Type: chain
End: 1312
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Protein
Q99M38
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: false
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Protein Coding Gene
MGI:1916233 | Rint1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
E9PUJ2
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
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Protein
P70388
Organism: Mus musculus/domesticus
Length: 1312  
Fragment?: false
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Protein
A8Y5I3
Organism: Mus musculus/domesticus
Length: 657  
Fragment?: true
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Protein
Q5SV02
Organism: Mus musculus/domesticus
Length: 1312  
Fragment?: false
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Gene
100174798 | rint1.L
Type: gene
Organism: frog, African clawed
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Protein Domain
IPR022982 | Rad50_ATPase_archaeal
Type: Family
Description: Rad50 is involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site []. This entry represents Rad50 from archaea and some bacteria.
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Publication
17470549 | J:122805
First Author: Lin X
Year: 2007
Journal: Mol Cell Biol
Title: RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival.
Volume: 27
Issue: 13
Pages: 4905-16
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Publication
19409520 | -
First Author: Waltes R
Year: 2009
Journal: Am J Hum Genet
Title: Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.
Volume: 84
Issue: 5
Pages: 605-16
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Protein
P70388-4
Organism: Mus musculus/domesticus
Length: 496  
Fragment?: false
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Protein
P70388-3
Organism: Mus musculus/domesticus
Length: 426  
Fragment?: false
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Protein
P70388-2
Organism: Mus musculus/domesticus
Length: 1251  
Fragment?: false
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Gene
101750148 | LOC101750148
Type: gene
Organism: chicken
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Gene
108713276 | rad50.S
Type: gene
Organism: frog, African clawed
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Gene
108715097 | LOC108715097
Type: gene
Organism: frog, African clawed
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Gene
495064 | rad50.L
Type: gene
Organism: frog, African clawed
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Publication
28264000 | J:245196
First Author: Otterpohl KL
Year: 2017
Journal: PLoS One
Title: Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk.
Volume: 12
Issue: 3
Pages: e0172247
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Publication
17698079 | -
First Author: Ghosal G
Year: 2007
Journal: J Mol Biol
Title: The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity.
Volume: 372
Issue: 4
Pages: 864-82
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Publication
21734400 | -
First Author: Murk W
Year: 2011
Journal: Hum Hered
Title: Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.
Volume: 71
Issue: 2
Pages: 97-105
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Allele
Rad50<tm1Flv> | MGI:3527268
 
Name: RAD50 double strand break repair protein; targeted mutation 1, Richard A Flavell
Allele Type: Targeted
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Publication
11371344 | -
First Author: Hopfner KP
Year: 2001
Journal: Cell
Title: Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Volume: 105
Issue: 4
Pages: 473-85
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Protein
Q8BZ36
Organism: Mus musculus/domesticus
Length: 792  
Fragment?: false
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Allele
Rint1<+> | MGI:3616052
 
Name: RAD50 interactor 1; wild type
Allele Type: Not Specified
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Publication
15135728 | -
First Author: Gorski MM
Year: 2004
Journal: DNA Repair (Amst)
Title: Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae.
Volume: 3
Issue: 6
Pages: 603-15
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Protein
Q8BZ36-2
Organism: Mus musculus/domesticus
Length: 734  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0027000 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029309 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028441 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom