| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Very strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1753724 |
| Pattern: |
Non-Uniform |
| Stage: |
TS24 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 16.5 |
| Image: |
Rasgrf1 - E16.5 |
| Note: |
Staining is very strong in the MZ of PVH & ARH nuclei, strong in SCH nucleus, strong & scattered in DMH nucleus, moderate in dorsal & ventral POAs, moderate & scattered in DAH, weak & scattered in AVH & either absent or ubiquitous in VMH nucleus & PH. |
| Specimen Label: |
Rasgrf1 - E16.5 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691319 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 11.5 |
| Image: |
Rasgrf1 - E11.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences. |
| Specimen Label: |
Rasgrf1 - E11.5 |
|
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271820 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 12.5 |
| Image: |
Rasgrf1 - E12.5 |
| Note: |
Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT. |
| Specimen Label: |
Rasgrf1 - E12.5 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271824 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 16.5 |
| Image: |
Rasgrf1 - E16.5 |
| Note: |
There is strong staining in the mantle zone of the premam zone. |
| Specimen Label: |
Rasgrf1 - E16.5 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1753920 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 12.5 |
| Image: |
Rasgrf1 - E12.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
| Specimen Label: |
Rasgrf1 - E12.5 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1753922 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 14.5 |
| Image: |
Rasgrf1 - E14.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
| Specimen Label: |
Rasgrf1 - E14.5 |
|
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691119 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 11.5 |
| Image: |
Rasgrf1 - E11.5 |
| Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences. |
| Specimen Label: |
Rasgrf1 - E11.5 |
|
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 14.5 |
| Image: |
Rasgrf1 - E14.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
| Specimen Label: |
Rasgrf1 - E14.5 |
|
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754724 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 16.5 |
| Image: |
Rasgrf1 - E16.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex. |
| Specimen Label: |
Rasgrf1 - E16.5 |
|
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271020 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 12.5 |
| Image: |
Rasgrf1 - E12.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT. |
| Specimen Label: |
Rasgrf1 - E12.5 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271024 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 16.5 |
| Image: |
Rasgrf1 - E16.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular zone of the premam zone. |
| Specimen Label: |
Rasgrf1 - E16.5 |
|
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266520 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 12.5 |
| Image: |
Rasgrf1 - E12.5 |
| Note: |
Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences. |
| Specimen Label: |
Rasgrf1 - E12.5 |
|
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3266524 |
| Pattern: |
Non-Uniform |
| Stage: |
TS24 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 16.5 |
| Image: |
Rasgrf1 - E16.5 |
| Note: |
There is strong staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences. |
| Specimen Label: |
Rasgrf1 - E16.5 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754120 |
| Pattern: |
Non-Uniform |
| Stage: |
TS20 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 12.5 |
| Image: |
Rasgrf1 - E12.5 |
| Note: |
There is weak staining in the mantle zone of the prethalamus. Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus. |
| Specimen Label: |
Rasgrf1 - E12.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4442727 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-05-13 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754122 |
| Pattern: |
Non-Uniform |
| Stage: |
TS22 |
| Assay Id: |
MGI:4450904 |
| Age: |
embryonic day 14.5 |
| Image: |
Rasgrf1 - E14.5 |
| Note: |
There is moderate staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus. |
| Specimen Label: |
Rasgrf1 - E14.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoon B |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. |
| Volume: |
25 |
| Issue: |
24 |
| Pages: |
11184-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Drake NM |
| Year: |
2011 |
| Journal: |
Genes Brain Behav |
| Title: |
Imprinted Rasgrf1 expression in neonatal mice affects olfactory learning and memory. |
| Volume: |
10 |
| Issue: |
4 |
| Pages: |
392-403 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernández-Medarde A |
| Year: |
2009 |
| Journal: |
J Neurochem |
| Title: |
RasGRF1 disruption causes retinal photoreception defects and associated transcriptomic alterations. |
| Volume: |
110 |
| Issue: |
2 |
| Pages: |
641-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
de la Puente A |
| Year: |
2002 |
| Journal: |
Gene |
| Title: |
Structural characterization of Rasgrf1 and a novel linked imprinted locus. |
| Volume: |
291 |
| Issue: |
1-2 |
| Pages: |
287-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fam NP |
| Year: |
1997 |
| Journal: |
Mol Cell Biol |
| Title: |
Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras. |
| Volume: |
17 |
| Issue: |
3 |
| Pages: |
1396-406 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Clapcott SJ |
| Year: |
2003 |
| Journal: |
Mamm Genome |
| Title: |
Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
495-505 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brideau CM |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
A non-coding RNA within the Rasgrf1 locus in mouse is imprinted and regulated by its homologous chromosome in trans. |
| Volume: |
5 |
| Issue: |
11 |
| Pages: |
e13784 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pearsall RS |
| Year: |
1999 |
| Journal: |
Genomics |
| Title: |
A direct repeat sequence at the Rasgrf1 locus and imprinted expression. |
| Volume: |
55 |
| Issue: |
2 |
| Pages: |
194-201 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Innocenti M |
| Year: |
1999 |
| Journal: |
FEBS Lett |
| Title: |
CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways. |
| Volume: |
460 |
| Issue: |
2 |
| Pages: |
357-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Crespo P |
| Year: |
2011 |
| Journal: |
Bioarchitecture |
| Title: |
Ras and Rho GTPases on the move: The RasGRF connection. |
| Volume: |
1 |
| Issue: |
4 |
| Pages: |
200-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fernández-Medarde A |
| Year: |
2011 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The RasGrf family of mammalian guanine nucleotide exchange factors. |
| Volume: |
1815 |
| Issue: |
2 |
| Pages: |
170-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Manyes L |
| Year: |
2018 |
| Journal: |
Brain Behav |
| Title: |
Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice. |
| Volume: |
8 |
| Issue: |
11 |
| Pages: |
e01089 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu LY |
| Year: |
2022 |
| Journal: |
Cancer Res |
| Title: |
Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis. |
| Volume: |
82 |
| Issue: |
22 |
| Pages: |
4153-4163 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsai TH |
| Year: |
2018 |
| Journal: |
Int J Mol Sci |
| Title: |
Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress. |
| Volume: |
19 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Watanabe T |
| Year: |
2011 |
| Journal: |
Science |
| Title: |
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. |
| Volume: |
332 |
| Issue: |
6031 |
| Pages: |
848-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Baldassa S |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
SCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowth. |
| Volume: |
282 |
| Issue: |
4 |
| Pages: |
2333-45 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
461
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
248
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1262
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1262
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheng Y |
| Year: |
2020 |
| Journal: |
Gene |
| Title: |
RasGRF1 participates in the protective effect of tanshinone IIA on depressive like behaviors of a chronic unpredictable mild stress induced mouse model. |
| Volume: |
754 |
|
| Pages: |
144817 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689419 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:6191191 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S2 - E11.5 - Rasgrf1 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689421 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6191191 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
Table S2 - E13.5 - Rasgrf1 |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689424 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:6191191 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
Table S2 - E15.5 - Rasgrf1 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689426 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:6191191 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
Table S2 - E18.5 - Rasgrf1 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6191191 |
| Age: |
postnatal day 4 |
|
|
| Specimen Label: |
Table S2 - P4 - Rasgrf1 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6191191 |
| Age: |
postnatal day 14 |
|
|
| Specimen Label: |
Table S2 - P14 - Rasgrf1 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6181933 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-07-25 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6191191 |
| Age: |
postnatal day 28 |
|
|
| Specimen Label: |
Table S2 - P28 - Rasgrf1 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Calvo F |
| Year: |
2011 |
| Journal: |
Nat Cell Biol |
| Title: |
RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation. |
| Volume: |
13 |
| Issue: |
7 |
| Pages: |
819-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ruiz-DeDiego I |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
15381 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Herman H |
| Year: |
2003 |
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| Protein Coding Gene |
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protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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| Protein Coding Gene |
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protein_coding_gene |
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mouse, laboratory |
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| Protein Coding Gene |
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protein_coding_gene |
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mouse, laboratory |
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| Protein Coding Gene |
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protein_coding_gene |
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mouse, laboratory |
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| Protein Coding Gene |
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protein_coding_gene |
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mouse, laboratory |
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| Protein Coding Gene |
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mouse, laboratory |
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