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Search results 101 to 166 out of 166 for Rbbp8

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Type Details Score
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Coding Gene
MGI:3606212 | Rbbp8nl
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
690416 | Rbbp8nl
Type: gene
Organism: rat
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Gene
485960 | RBBP8NL
Type: gene
Organism: dog, domestic
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Gene
737961 | RBBP8NL
Type: gene
Organism: chimpanzee
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Gene
515877 | RBBP8NL
Type: gene
Organism: cattle
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Gene
100430426 | RBBP8NL
Type: gene
Organism: macaque, rhesus
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Gene
101747728 | RBBP8NL
Type: gene
Organism: chicken
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Gene
394605 | rbbp8nl
Type: gene
Organism: frog, western clawed
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Protein
A2ABX0
Organism: Mus musculus/domesticus
Length: 614  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: DNA endonuclease RBBP8
Type: chain
End: 893
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Gene
108700922 | rbbp8nl.L
Type: gene
Organism: frog, African clawed
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Gene
108702620 | rbbp8nl.S
Type: gene
Organism: frog, African clawed
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Allele
Rbbp8nl<+> | MGI:5444477
 
Name: RBBP8 N-terminal like; wild type
Allele Type: Not Specified
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Publication
20829486 | J:163815
First Author: Kaidi A
Year: 2010
Journal: Science
Title: Human SIRT6 promotes DNA end resection through CtIP deacetylation.
Volume: 329
Issue: 5997
Pages: 1348-53
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Publication
30975768 | -
First Author: Kaidi A
Year: 2019
Journal: Science
Title: Retraction.
Volume: 364
Issue: 6437
Pages: 247
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Publication
21131978 | -
First Author: Zhang Y
Year: 2011
Journal: Nat Struct Mol Biol
Title: An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway.
Volume: 18
Issue: 1
Pages: 80-4
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Publication
21131982 | -
First Author: Lee-Theilen M
Year: 2011
Journal: Nat Struct Mol Biol
Title: CtIP promotes microhomology-mediated alternative end joining during class-switch recombination.
Volume: 18
Issue: 1
Pages: 75-9
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Protein
A0A3Q4EBX2
Organism: Mus musculus/domesticus
Length: 26  
Fragment?: true
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Allele
Rbbp8nl<em1(IMPC)J> | MGI:6268411
Name: RBBP8 N-terminal like; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Coding Gene
MGP_129S1SvImJ_G0026992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026928 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3606212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027413 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026808 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027472 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026225 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025703 | -
Type: protein_coding_gene
Organism: Mus spretus
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Allele
Rbbp8nl<tm1a(EUCOMM)Hmgu> | MGI:4452733
Name: RBBP8 N-terminal like; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Rbbp8nl<tm1e(EUCOMM)Hmgu> | MGI:4460363
Name: RBBP8 N-terminal like; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:6268417 | C57BL/6NJ-Rbbp8nl<em1(IMPC)J>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Rbbp8nl<em3Gpt> | MGI:7305231
Name: RBBP8 N-terminal like; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Rbbp8nl/Rbbp8nl
Background: C57BL/6NJ-Rbbp8nl/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Allele
Rbbp8<em2Smoc> | MGI:7291987
Name: retinoblastoma binding protein 8, endonuclease; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0070013 | Seckel syndrome 2
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Strain
MGI:6476149 | C57BL/6JSmoc-Rbbp8<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Rbbp8<em1Smoc> | MGI:7291986
Name: retinoblastoma binding protein 8, endonuclease; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6429466 | C57BL/6JSmoc-Rbbp8<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein Domain
IPR033316 | RBBP8-like
Type: Family
Description: This entry includes DNA endonuclease RBBP8 from animals, Ctp1 from fission yeast and protein gamma response 1 from plants []. This entry also includes human RBBP8 N-terminal-like protein (RBBP8NL) whose function is not clear. RBBP8 is an endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends []. Ctp1 is an endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of rec12 from the break sites and ensuring both resection and intrachromosomal association of the broken ends [].
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Publication
11023598 | -
First Author: Deveaux Y
Year: 2000
Journal: Radiat Res
Title: Molecular cloning and developmental expression of AtGR1, a new growth-related Arabidopsis gene strongly induced by ionizing radiation.
Volume: 154
Issue: 4
Pages: 355-64
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Protein
Q8CEB4
Organism: Mus musculus/domesticus
Length: 614  
Fragment?: false
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Publication
17936710 | -
First Author: Limbo O
Year: 2007
Journal: Mol Cell
Title: Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.
Volume: 28
Issue: 1
Pages: 134-46
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Publication
16374511 | -
First Author: Clerici M
Year: 2006
Journal: EMBO Rep
Title: The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling.
Volume: 7
Issue: 2
Pages: 212-8
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Publication
16162495 | -
First Author: Clerici M
Year: 2005
Journal: J Biol Chem
Title: The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends.
Volume: 280
Issue: 46
Pages: 38631-8
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Publication
18042458 | -
First Author: Lengsfeld BM
Year: 2007
Journal: Mol Cell
Title: Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex.
Volume: 28
Issue: 4
Pages: 638-51
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Publication
33836577 | -
 
First Author: Zdravković A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: A conserved Ctp1/CtIP C-terminal peptide stimulates Mre11 endonuclease activity.
Volume: 118
Issue: 11
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Protein Domain
IPR013882 | Ctp1_C
Type: Domain
Description: This entry represents the C-terminal domain of the fission yeast Ctip (Ctp1) protein. Proteins containing this domain include DNA endonuclease RBBP8 (also known as CtBP-interacting protein, CtIP) from animals, protein gamma response 1 (GR1) from Arabidopsis and SAE2 from S. cerevisiae [, ]. SAE2 is a protein involved in repairing meiotic and mitotic double-strand breaks in DNA [, , ].Although proteins containing this domain were described as endonucleases, it is now known that they actually function as endonuclease activators that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends [, , ]. This domain contains highly conserved residues at its 15-residue extreme that are indispensable for MRN (Mre11-Rad50-Nbs1) complex activation, through the stimulation of Mre11 endonuclease activity [].
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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