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Search results 101 to 184 out of 184 for Rbck1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4885401
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945914
Age: postnatal day 7
Image: g01957 P7
Specimen Label: g01957 P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4885401
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945914
Age: postnatal day 42
Image: g01957 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01957 Adult
Detected: true
Specimen Num: 4
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Publication
32393887 | J:291215
First Author: Fuseya Y
Year: 2020
Journal: Nat Cell Biol
Title: The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.
Volume: 22
Issue: 6
Pages: 663-673
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Publication
17069764 | J:116556
First Author: Nakamura M
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.
Volume: 351
Issue: 2
Pages: 340-7
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Publication
17682061 | J:126690
First Author: Zenke-Kawasaki Y
Year: 2007
Journal: Mol Cell Biol
Title: Heme induces ubiquitination and degradation of the transcription factor Bach1.
Volume: 27
Issue: 19
Pages: 6962-71
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Publication
26525107 | J:228041
 
First Author: Klein T
Year: 2015
Journal: Nat Commun
Title: The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.
Volume: 6
Pages: 8777
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Publication
24958845 | J:214522
First Author: Rodgers MA
Year: 2014
Journal: J Exp Med
Title: The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.
Volume: 211
Issue: 7
Pages: 1333-47
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Publication
26976635 | J:236193
First Author: Shimizu S
Year: 2016
Journal: Mol Cell Biol
Title: Differential Involvement of the Npl4 Zinc Finger Domains of SHARPIN and HOIL-1L in Linear Ubiquitin Chain Assembly Complex-Mediated Cell Death Protection.
Volume: 36
Issue: 10
Pages: 1569-83
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Publication
23942237 | J:201885
First Author: Sasaki Y
Year: 2013
Journal: EMBO J
Title: Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.
Volume: 32
Issue: 18
Pages: 2463-76
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Publication
29109255 | J:254318
First Author: Magnani ND
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.
Volume: 114
Issue: 47
Pages: E10178-E10186
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Publication
32123171 | J:286745
First Author: Zuo Y
Year: 2020
Journal: Nat Commun
Title: Regulation of the linear ubiquitination of STAT1 controls antiviral interferon signaling.
Volume: 11
Issue: 1
Pages: 1146
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Publication
29694895 | J:270829
First Author: Fujita H
Year: 2018
Journal: Cell Rep
Title: Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.
Volume: 23
Issue: 4
Pages: 1192-1204
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Publication
37902285 | J:346641
First Author: Hartley VL
Year: 2023
Journal: J Immunol
Title: HOIL1 Regulates Group 3 Innate Lymphoid Cells in the Colon and Protects against Systemic Dissemination, Colonic Ulceration, and Lethality from Citrobacter rodentium Infection.
Volume: 211
Issue: 12
Pages: 1823-1834
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Publication
31714898 | J:297211
First Author: Brazee PL
Year: 2020
Journal: J Clin Invest
Title: Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection.
Volume: 130
Issue: 3
Pages: 1301-1314
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Publication
21292167 | J:170856
First Author: Inn KS
Year: 2011
Journal: Mol Cell
Title: Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction.
Volume: 41
Issue: 3
Pages: 354-65
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Publication
10431818 | J:56275
First Author: Martinez-Noel G
Year: 1999
Journal: FEBS Lett
Title: A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.
Volume: 454
Issue: 3
Pages: 257-61
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Publication
20005846 | J:155446
First Author: Haas TL
Year: 2009
Journal: Mol Cell
Title: Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.
Volume: 36
Issue: 5
Pages: 831-44
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Publication
25599590 | J:219574
   
First Author: MacDuff DA
Year: 2015
Journal: Elife
Title: Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection.
Volume: 4
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Publication
34755089 | J:319466
First Author: Gomez-Diaz C
Year: 2021
Journal: iScience
Title: The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains.
Volume: 24
Issue: 11
Pages: 103241
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Publication
25284787 | J:238820
First Author: Peltzer N
Year: 2014
Journal: Cell Rep
Title: HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.
Volume: 9
Issue: 1
Pages: 153-65
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Publication
24461064 | J:215707
First Author: Takiuchi T
Year: 2014
Journal: Genes Cells
Title: Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.
Volume: 19
Issue: 3
Pages: 254-72
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Publication
16670015 | J:111441
 
First Author: Farber CR
Year: 2006
Journal: BMC Genomics
Title: Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains.
Volume: 7
Pages: 102
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Publication
30254289 | J:267737
First Author: Taraborrelli L
Year: 2018
Journal: Nat Commun
Title: LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.
Volume: 9
Issue: 1
Pages: 3910
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Publication
22089168 | J:202809
 
First Author: Vanlangenakker N
Year: 2011
Journal: Cell Death Dis
Title: TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members.
Volume: 2
Pages: e230
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Publication
19136968 | J:158069
First Author: Tokunaga F
Year: 2009
Journal: Nat Cell Biol
Title: Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.
Volume: 11
Issue: 2
Pages: 123-32
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Publication
29695863 | J:261640
First Author: Peltzer N
Year: 2018
Journal: Nature
Title: LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Volume: 557
Issue: 7703
Pages: 112-117
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Publication
30209176 | J:267867
 
First Author: MacDuff DA
Year: 2018
Journal: J Virol
Title: HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection.
Volume: 92
Issue: 23
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Publication
30755793 | J:341418
   
First Author: Holbrook J
Year: 2019
Journal: F1000Res
Title: Tumour necrosis factor signalling in health and disease.
Volume: 8
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Publication
20614026 | J:161997
First Author: Hostager BS
Year: 2010
Journal: PLoS One
Title: HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.
Volume: 5
Issue: 6
Pages: e11380
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Publication
34157307 | J:308817
First Author: Fu Y
Year: 2021
Journal: Mol Cell
Title: OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin.
Volume: 81
Issue: 15
Pages: 3187-3204.e7
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Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
20103625 | -
First Author: Gustafsson N
Year: 2010
Journal: Cancer Res
Title: RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor alpha and cyclin B1.
Volume: 70
Issue: 3
Pages: 1265-74
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Interaction Experiment
Landgraf K (2010)
Description: Sipl1 and Rbck1 are novel Eya1-binding proteins with a role in craniofacial development.
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GXD Expression
GXD Expression
 
Probe: MGI:7567658
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3559221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7567673
Age: embryonic day 13.5
Note: Co-expression with Sipl1 and Rbck1 in developing nephrons in outer region of kidney.
Specimen Label: 3C Eya1 kidney
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7567659
Assay Type: RNA in situ
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3559221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7567674
Age: embryonic day 13.5
Note: Co-expression with Eya1 and Rbck1 in developing nephrons in outer region of kidney.
Specimen Label: 3C Sipl1 kidney
Detected: true
Specimen Num: 2
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Allele
Rbck1<em1Smoc> | MGI:7291988
Name: RanBP-type and C3HC4-type zinc finger containing 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
17449468 | -
First Author: Tian Y
Year: 2007
Journal: J Biol Chem
Title: RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation.
Volume: 282
Issue: 23
Pages: 16776-82
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Strain
MGI:6355148 | C57BL/6JSmoc-Rbck1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
21455173 | J:170810
First Author: Gerlach B
Year: 2011
Journal: Nature
Title: Linear ubiquitination prevents inflammation and regulates immune signalling.
Volume: 471
Issue: 7340
Pages: 591-6
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Publication
28978479 | -
First Author: Liu J
Year: 2017
Journal: Cell Rep
Title: Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly.
Volume: 21
Issue: 1
Pages: 27-36
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Protein Domain
IPR026261 | RBCK1/SHARPIN
Type: Family
Description: This entry consists of RanBP-type and C3HC4-type zinc finger-containing protein 1 (RBCK1, also known as HOIL-1) and SHARPIN. Both are components of the E3 ligase complex LUBAC (linear ubiquitin chain assembly complex). LUBAC is composed of HOIP, RBCK1/HOIL-1, and SHARPIN. HOIP is the catalytic subunit and its E3 activity can be effectively activated by HOIL-1 or SHARPIN []. The LUBAC complex catalyses the formation of linear ubiquitin chains and regulates immune and apoptopic signaling pathways [, , ].RBCK1/HOIL-1 contains an ubiquitin-like (UBL) domain followed by a Npl4 zinc finger (NZF) domain and a RBR (RING-between-RING) domain in the C-terminal portion of the protein. RBCK1 is a RING-between-RING E3 ligase, and it has also been shown to act as a transcriptional activator []. SHARPIN also contains a UBL domain and a Ub-binding NZF domain, but lacks the RBR domain and has a additional N-terminal pleckstrin homology (PH) domain [, ].
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Publication
21829440 | J:176256
First Author: Liang Y
Year: 2011
Journal: PLoS One
Title: SHARPIN negatively associates with TRAF2-mediated NFκB activation.
Volume: 6
Issue: 7
Pages: e21696
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Publication
32907941 | J:296365
First Author: Liu W
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: LncRNA Malat1 inhibition of TDP43 cleavage suppresses IRF3-initiated antiviral innate immunity.
Volume: 117
Issue: 38
Pages: 23695-23706
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Publication
32442483 | J:300084
First Author: Wang P
Year: 2020
Journal: Semin Cancer Biol
Title: RBR E3 ubiquitin ligases in tumorigenesis.
Volume: 67
Issue: Pt 2
Pages: 131-144
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Publication
22549881 | -
First Author: Stieglitz B
Year: 2012
Journal: J Biol Chem
Title: Structural analysis of SHARPIN, a subunit of a large multi-protein E3 ubiquitin ligase, reveals a novel dimerization function for the pleckstrin homology superfold.
Volume: 287
Issue: 25
Pages: 20823-9
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Protein
Q91WA6
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein
F6UHH8
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Protein
F6VII1
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: true
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Protein
Q9WUB0
Organism: Mus musculus/domesticus
Length: 508  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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