Type |
Details |
Score |
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7425117 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7425169 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Emx1-Cre; Rbm8a lox/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7425119 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7425170 |
Age: |
embryonic day 11.5 |
Image: |
4 |
|
Specimen Label: |
Emx1-Cre; Rbm8a lox/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7425121 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7425171 |
Age: |
embryonic day 11.5 |
Image: |
S2 |
|
Specimen Label: |
Emx1-Cre; Rbm8a lox/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7425122 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7425172 |
Age: |
embryonic day 11.5 |
Image: |
S2 |
|
Specimen Label: |
Emx1-Cre; Rbm8a lox/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7425125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7425175 |
Age: |
embryonic day 11.5 |
Image: |
6 |
|
Specimen Label: |
Emx1-Cre; Rbm8a lox/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7425125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7425175 |
Age: |
embryonic day 11.5 |
Image: |
6 |
|
Specimen Label: |
Emx1-Cre; Rbm8a lox/+ |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Salicioni AM |
Year: |
2000 |
Journal: |
Genomics |
Title: |
Identification and structural analysis of human RBM8A and RBM8B: two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor. |
Volume: |
69 |
Issue: |
1 |
Pages: |
54-62 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
173
 |
Fragment?: |
false |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Robbins J |
Year: |
1991 |
Journal: |
Cell |
Title: |
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. |
Volume: |
64 |
Issue: |
3 |
Pages: |
615-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mohr SE |
Year: |
2001 |
Journal: |
Genes Dev |
Title: |
The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis. |
Volume: |
15 |
Issue: |
21 |
Pages: |
2886-99 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
RNA-binding motif protein 8 (RBM8), also termed binder of OVCA1-1 (BOV-1) or RNA-binding protein Y14, is one of the components of the exon-exon junction complex (EJC) []. It has two isoforms, RBM8A and RBM8B, both of which are identical except that RBM8B is 16 amino acids shorter at its N terminus []. Three-dimensional modelling of the RBM8 RRM domain indicates that the sequences fold into an RNA-binding domain, forming a hydrophobic core between a β-sheet and two helices. The human RBM8A protein is ubiquitously expressed; the protein is localised predominantly in the cell nucleus and diffused throughout the cytoplasm []. It preferentially associates with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. Evidence suggests the protein remains associated with spliced mRNAs as a tag to indicate the position of spliced introns. Human RBM8A protein specifically binds to MAGOH, the human homologue of Drosophila mago nashi, a protein required for normal germ plasm development in the Drosophila embryo []; a similar association occurs with the Drosophila RBM8 protein, Tsunagi []. The RBM8A and RBM8B protein sequences contain a putative bipartite nuclear localisation signal []at the N terminus, as well a stretch of glycine residues. In addition, the RRM contained within RBM8A and RBM8B contains one set of the two consensus nucleic acid-binding motifs, RNP-1 and RNP-2, characteristic of heterogeneous nuclear ribonucleoprotein (hnRNP). |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhan X |
Year: |
2018 |
Journal: |
Science |
Title: |
Structure of a human catalytic step I spliceosome. |
Volume: |
359 |
Issue: |
6375 |
Pages: |
537-545 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
171
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
125
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Mao H |
Year: |
2017 |
Journal: |
RNA |
Title: |
Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. |
Volume: |
23 |
Issue: |
1 |
Pages: |
23-31 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490513 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490513 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490513 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490513 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490513 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490513 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287423 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5490520 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287424 |
|
Stage: |
TS24 |
Assay Id: |
MGI:5490520 |
Age: |
embryonic day 16.5 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283425 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5490520 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283425 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5490520 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283425 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5490520 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5490520 |
Age: |
postnatal newborn |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5490520 |
Age: |
postnatal newborn |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5490520 |
Age: |
postnatal newborn |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3578428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490579 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3578428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490579 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490489 |
Assay Type: |
RT-PCR |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3577728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5490579 |
Age: |
postnatal adult |
|
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1907828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5M |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283425 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:5490550 |
Age: |
embryonic day 17.0 |
|
Note: |
Expression was predominantly in the epithelial cells of the developing villus. |
Specimen Label: |
5K |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3578427 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal day 1 |
|
Note: |
Expression was predominantly in the epithelial cells of the villus. |
Specimen Label: |
5L |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3578428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5M |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3578428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5N |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3578428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5O |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3577728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5O |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1866828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5N |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5490504 |
Assay Type: |
RNA in situ |
Annotation Date: |
2013-06-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1866828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5490550 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5O |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nielsen KH |
Year: |
2009 |
Journal: |
RNA |
Title: |
Mechanism of ATP turnover inhibition in the EJC. |
Volume: |
15 |
Issue: |
1 |
Pages: |
67-75 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry corresponds to the RNA recognition motif of RBM8. RNA-binding protein RBM8, also termed binder of OVCA1-1 (BOV-1) or RNA-binding protein Y14, is one of the components of the exon-exon junction complex (EJC) []. It has two isoforms, RBM8A and RBM8B, both of which are identical except that RBM8B is 16 amino acids shorter at its N terminus []. RBM8, together with other EJC components (such as Magoh, Aly/REF, RNPS1, Srm160, and Upf3), plays critical roles in postsplicing processing, including nuclear export and cytoplasmic localization of the mRNA, and the nonsense-mediated mRNA decay (NMD) surveillance process. RBM8 binds to mRNA 20-24 nucleotides upstream of a spliced exon-exon junction. It is also involved in spliced mRNA nuclear export, and the process of nonsense-mediated decay of mRNAs with premature stop codons. RBM8 forms a specific heterodimer complex with the EJC protein Magoh which then associates with Aly/REF, RNPS1, DEK, and SRm160 on the spliced mRNA, and inhibits ATP turnover by eIF4AIII, thereby trapping the EJC core onto RNA [, ].RBM8 contains an N-terminal putative bipartite nuclear localization signal, one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), in the central region, and a C-terminal serine-arginine rich region (SR domain) and glycine-arginine rich region (RG domain) []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Lau CK |
Year: |
2003 |
Journal: |
Curr Biol |
Title: |
Structure of the Y14-Magoh core of the exon junction complex. |
Volume: |
13 |
Issue: |
11 |
Pages: |
933-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Islam S |
Year: |
2005 |
Journal: |
J Histochem Cytochem |
Title: |
Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. |
Volume: |
53 |
Issue: |
12 |
Pages: |
1501-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|