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Search results 101 to 200 out of 248 for Rgs9

0.027s
Type Details Score
GXD Expression  
Probe: MGI:4885802
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944919
Age: embryonic day 15.5
Image: g00356 E15.5
Specimen Label: g00356 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4885802
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944919
Age: embryonic day 15.5
Image: g00356 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00356 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4885802
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944919
Age: postnatal day 7
Image: g00356 P7
Specimen Label: g00356 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4885802
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944919
Age: postnatal day 42
Image: g00356 Adult
Specimen Label: g00356 Adult
Detected: true
Specimen Num: 4
Publication
First Author: Song JH
Year: 2006
Journal: J Biol Chem
Title: Subcellular targeting of RGS9-2 is controlled by multiple molecular determinants on its membrane anchor, R7BP.
Volume: 281
Issue: 22
Pages: 15361-9
Publication
First Author: Keresztes G
Year: 2003
Journal: Mol Cell Neurosci
Title: Expression patterns of the RGS9-1 anchoring protein R9AP in the chicken and mouse suggest multiple roles in the nervous system.
Volume: 24
Issue: 3
Pages: 687-95
Publication
First Author: Wang N
Year: 2014
Journal: Nat Med
Title: Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Volume: 20
Issue: 5
Pages: 536-41
Publication
First Author: Chen CK
Year: 2010
Journal: J Physiol
Title: Replacing the rod with the cone transducin subunit decreases sensitivity and accelerates response decay.
Volume: 588
Issue: Pt 17
Pages: 3231-41
Publication
First Author: Mitsi V
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states.
Volume: 112
Issue: 36
Pages: E5088-97
Publication
First Author: Yokoi F
Year: 2012
Journal: Hum Mol Genet
Title: Abnormal nuclear envelopes in the striatum and motor deficits in DYT11 myoclonus-dystonia mouse models.
Volume: 21
Issue: 4
Pages: 916-25
Publication
First Author: Geddes CE
Year: 2018
Journal: Cell
Title: Optogenetic Editing Reveals the Hierarchical Organization of Learned Action Sequences.
Volume: 174
Issue: 1
Pages: 32-43.e15
Publication
First Author: Cui Y
Year: 2014
Journal: Nat Neurosci
Title: Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward.
Volume: 17
Issue: 2
Pages: 254-61
Publication
First Author: Dickey AS
Year: 2016
Journal: Nat Med
Title: PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.
Volume: 22
Issue: 1
Pages: 37-45
Publication
First Author: Xie K
Year: 2016
Journal: Curr Biol
Title: NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.
Volume: 26
Issue: 22
Pages: 2992-3003
Publication
First Author: Sutton LP
Year: 2019
Journal: PLoS Biol
Title: NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.
Volume: 17
Issue: 10
Pages: e3000477
Publication  
First Author: Radke AK
Year: 2017
Journal: Alcohol
Title: Reduced ethanol drinking following selective cortical interneuron deletion of the GluN2B NMDA receptors subunit.
Volume: 58
Pages: 47-51
Publication
First Author: Brigman JL
Year: 2013
Journal: Nat Neurosci
Title: GluN2B in corticostriatal circuits governs choice learning and choice shifting.
Volume: 16
Issue: 8
Pages: 1101-10
Publication
First Author: Tsang SH
Year: 2006
Journal: J Neurosci
Title: GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase.
Volume: 26
Issue: 17
Pages: 4472-80
Publication
First Author: Anderson GR
Year: 2007
Journal: J Neurosci
Title: Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.
Volume: 27
Issue: 51
Pages: 14117-27
Publication
First Author: Dang MT
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum.
Volume: 103
Issue: 41
Pages: 15254-9
Publication  
First Author: Liu J
Year: 2020
Journal: Neurobiol Dis
Title: Striatal glutamate delta-1 receptor regulates behavioral flexibility and thalamostriatal connectivity.
Volume: 137
Pages: 104746
Publication
First Author: Koralek AC
Year: 2012
Journal: Nature
Title: Corticostriatal plasticity is necessary for learning intentional neuroprosthetic skills.
Volume: 483
Issue: 7389
Pages: 331-5
Publication
First Author: Jin X
Year: 2010
Journal: Nature
Title: Start/stop signals emerge in nigrostriatal circuits during sequence learning.
Volume: 466
Issue: 7305
Pages: 457-62
Publication
First Author: Jin X
Year: 2014
Journal: Nat Neurosci
Title: Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences.
Volume: 17
Issue: 3
Pages: 423-30
Publication
First Author: Muntean BS
Year: 2021
Journal: Cell Rep
Title: Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders.
Volume: 34
Issue: 5
Pages: 108718
Publication
First Author: Liao GY
Year: 2013
Journal: Mol Metab
Title: Ablation of TrkB expression in RGS9-2 cells leads to hyperphagic obesity.
Volume: 2
Issue: 4
Pages: 491-7
Publication
First Author: Garzón J
Year: 2005
Journal: J Biol Chem
Title: Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization.
Volume: 280
Issue: 10
Pages: 8951-60
Publication
First Author: Howard CD
Year: 2017
Journal: Neuron
Title: Dynamic Nigrostriatal Dopamine Biases Action Selection.
Volume: 93
Issue: 6
Pages: 1436-1450.e8
Publication
First Author: Urbanus BHA
Year: 2020
Journal: Sci Rep
Title: Region-specific Foxp2 deletions in cortex, striatum or cerebellum cannot explain vocalization deficits observed in spontaneous global knockouts.
Volume: 10
Issue: 1
Pages: 21631
Publication  
First Author: Kool MJ
Year: 2016
Journal: Sci Rep
Title: The molecular, temporal and region-specific requirements of the beta isoform of Calcium/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion.
Volume: 6
Pages: 26989
Publication
First Author: Lobanova ES
Year: 2010
Journal: J Neurosci
Title: Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light.
Volume: 30
Issue: 20
Pages: 6815-24
Publication  
First Author: Wilkes BJ
Year: 2021
Journal: Exp Neurol
Title: Cell-specific effects of Dyt1 knock-out on sensory processing, network-level connectivity, and motor deficits.
Volume: 343
Pages: 113783
Publication  
First Author: Lyu S
Year: 2019
Journal: eNeuro
Title: The Role of BTBD9 in Striatum and Restless Legs Syndrome.
Volume: 6
Issue: 5
Publication
First Author: French CA
Year: 2019
Journal: Mol Psychiatry
Title: Differential effects of Foxp2 disruption in distinct motor circuits.
Volume: 24
Issue: 3
Pages: 447-462
Publication
First Author: Yokoi F
Year: 2011
Journal: PLoS One
Title: Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice.
Volume: 6
Issue: 9
Pages: e24539
Publication
First Author: Sutton LP
Year: 2016
Journal: Biol Psychiatry
Title: Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum.
Volume: 80
Issue: 3
Pages: 235-45
Publication  
First Author: Pandey M
Year: 2023
Journal: JCI Insight
Title: Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors.
Volume: 8
Issue: 13
Publication
First Author: Tian M
Year: 2013
Journal: PLoS One
Title: Light-induced translocation of RGS9-1 and Gβ5L in mouse rod photoreceptors.
Volume: 8
Issue: 3
Pages: e58832
Publication  
First Author: Bonsi P
Year: 2019
Journal: EMBO Mol Med
Title: RGS9-2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models.
Volume: 11
Issue: 1
Publication
First Author: Mathur BN
Year: 2013
Journal: Nat Neurosci
Title: Voltage drives diverse endocannabinoid signals to mediate striatal microcircuit-specific plasticity.
Volume: 16
Issue: 9
Pages: 1275-83
Publication    
First Author: Xie K
Year: 2015
Journal: Elife
Title: Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling.
Volume: 4
Publication
First Author: Marcott PF
Year: 2018
Journal: Neuron
Title: Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens.
Volume: 98
Issue: 3
Pages: 575-587.e4
Publication  
First Author: Liu Y
Year: 2021
Journal: Behav Brain Res
Title: Investigating the role of striatal dopamine receptor 2 in motor coordination and balance: Insights into the pathogenesis of DYT1 dystonia.
Volume: 403
Pages: 113137
Publication
First Author: Davis MI
Year: 2018
Journal: PLoS One
Title: The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra.
Volume: 13
Issue: 2
Pages: e0191436
Publication  
First Author: Liput DJ
Year: 2022
Journal: Neuropharmacology
Title: 2-Arachidonoylglycerol mobilization following brief synaptic stimulation in the dorsal lateral striatum requires glutamatergic and cholinergic neurotransmission.
Volume: 205
Pages: 108916
Publication
First Author: Anderson GR
Year: 2009
Journal: Mol Cell Biol
Title: Changes in striatal signaling induce remodeling of RGS complexes containing Gbeta5 and R7BP subunits.
Volume: 29
Issue: 11
Pages: 3033-44
Publication
First Author: Otsuki B
Year: 2007
Journal: J Bone Miner Res
Title: Quantitative trait locus that determines the cross-sectional shape of the femur in SAMP6 and SAMP2 mice.
Volume: 22
Issue: 5
Pages: 675-85
Publication
First Author: Nagata Y
Year: 2001
Journal: Blood
Title: A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes.
Volume: 97
Issue: 10
Pages: 3051-60
Publication
First Author: Niewiadomska-Cimicka A
Year: 2017
Journal: Mol Neurobiol
Title: Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.
Volume: 54
Issue: 5
Pages: 3859-3878
Publication
First Author: Maddala R
Year: 2021
Journal: Sci Rep
Title: Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.
Volume: 11
Issue: 1
Pages: 2203
Publication
First Author: Jelcick AS
Year: 2011
Journal: PLoS One
Title: Genetic variations strongly influence phenotypic outcome in the mouse retina.
Volume: 6
Issue: 7
Pages: e21858
Publication
First Author: Wang N
Year: 2022
Journal: Neuron
Title: Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.
Volume: 110
Issue: 20
Pages: 3318-3338.e9
Publication
First Author: Sierra DA
Year: 2002
Journal: Genomics
Title: Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Volume: 79
Issue: 2
Pages: 177-85
Publication
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 675  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 484  
Fragment?: false
Publication
First Author: Nishiguchi KM
Year: 2004
Journal: Nature
Title: Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation.
Volume: 427
Issue: 6969
Pages: 75-8
DO Term
Publication
First Author: Martemyanov KA
Year: 2003
Journal: J Neurosci
Title: The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo.
Volume: 23
Issue: 32
Pages: 10175-81
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Allele
Name: transgene insertion 1, Ching-Kang Chen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Protein
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
Protein Domain
Type: Family
Description: This family consists of regulator of G-protein signalling 7-binding protein (RGS7BP) and regulator of G-protein signalling 9-binding protein (RGS9BP). They interact with regulation of G-protein signalling (RGS) proteins and Gbeta5 to form complexes that act to regulate G-proteins [].RGS7BP is expressed neuronally []and interacts with R7 family of RGS proteins (RGS6, RGS7, RGS9 and RGS11). RGS9BP interacts with RGS9 and is involved in the regulation of G-protein signalling in the phototransduction, participating in the recovery phase of visual transduction [].
Protein
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
Publication
First Author: Cheever ML
Year: 2008
Journal: Nat Struct Mol Biol
Title: Crystal structure of the multifunctional Gbeta5-RGS9 complex.
Volume: 15
Issue: 2
Pages: 155-62
Protein Domain
Type: Domain
Description: This domain is found in RGS9 (Class C) regulator of G-protein signalling (RGS) protein present in Mus musculus. RGS proteins attenuate heterotrimeric G-protein signalling by enhancing the intrinsic GTPase activity of G-alpha subunits and are vital for proper signal transduction kinetics. The domain is referred to as DEP helical extension (DHEX) because it is located next to N-terminal Dishevelled/Egl-10/Pleckstrin homology (DEP) domain. Both the DEP and DHEX domains are necessary, but not sufficient, to bind anchoring proteins such as RGS9 anchor protein. DHEX has no close structural homologues [].
Allele
Name: guanine nucleotide binding protein (G protein), beta 5; targeted mutation 1, Ching-Kang Chen
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Hu G
Year: 2003
Journal: J Biol Chem
Title: Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP.
Volume: 278
Issue: 16
Pages: 14550-4
Protein Domain
Type: Family
Description: This entry represents regulator of G-protein signalling 9-binding protein (RGS9BP), which is involved in regulation of signalling in phototransduction []. It interacts with the regulation of G-protein signalling 9 (RGS9) and Gbeta5 complex, anchoring it to photoreceptor disc membranes [], enhancing the ability of RGS9 to stimulate G protein GTPase activity, allowing the visual signal to be terminated in a timely manner [].
Publication
First Author: Cao Y
Year: 2009
Journal: J Neurosci
Title: Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons.
Volume: 29
Issue: 29
Pages: 9301-13