Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750322 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7260227 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627213 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:7260230 |
Age: |
embryonic day 8.75 |
Image: |
5G |
Note: |
Expression emerges in PA2 region at E8.75-9.0. |
Specimen Label: |
5G |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7260227 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627213 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:7260230 |
Age: |
embryonic day 8.75 |
Image: |
5G' |
Note: |
Expression emerges in PA2 region at E8.75-9.0. |
Specimen Label: |
5G' |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7260227 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627215 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:7260230 |
Age: |
embryonic day 9.25 |
Image: |
5I |
Note: |
Expression in second pouch and PA3 regions at E9.25. |
Specimen Label: |
5I |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7786642 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-12-11 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627214 |
|
Stage: |
TS14 |
Assay Id: |
MGI:7786645 |
Age: |
embryonic day 9.0 |
|
Note: |
The endodermal bending had not yet occurred at 17-somite stage. |
Specimen Label: |
1g |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7786642 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-12-11 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627214 |
|
Stage: |
TS14 |
Assay Id: |
MGI:7786645 |
Age: |
embryonic day 9.0 |
|
|
Specimen Label: |
S2A |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1775122 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1797222 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274122 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1776322 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1609217 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 10.5 |
Image: |
Dscr6 10.5dpc |
|
Specimen Label: |
Dscr6 10.5dpc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1832122 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666917 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 10.5 |
Image: |
Dscr6 10.5dpc |
|
Specimen Label: |
Dscr6 10.5dpc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 10.5 |
Image: |
Dscr6 10.5dpc |
|
Specimen Label: |
Dscr6 10.5dpc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7260227 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-04-08 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611713 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:7260230 |
Age: |
embryonic day 8.75 |
Image: |
5H |
Note: |
Expression decreased compared with heterozygote. |
Specimen Label: |
5H |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7260227 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-04-08 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611713 |
Pattern: |
Not Specified |
Stage: |
TS13 |
Assay Id: |
MGI:7260230 |
Age: |
embryonic day 8.75 |
Image: |
5H' |
Note: |
Expression decreased compared with heterozygote. |
Specimen Label: |
5H' |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7260227 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-04-08 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611715 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:7260230 |
Age: |
embryonic day 9.25 |
Image: |
5J |
Note: |
Expression barely detectable in posterior PA1 region. |
Specimen Label: |
5J |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1620122 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752522 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1668822 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757722 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689417 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 10.5 |
Image: |
Dscr6 10.5dpc |
|
Specimen Label: |
Dscr6 10.5dpc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2663646 |
Assay Type: |
RNA in situ |
Annotation Date: |
2003-07-21 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1796222 |
Pattern: |
Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:2666298 |
Age: |
embryonic day 14.5 |
Image: |
Dscr6 14.5dpc |
|
Specimen Label: |
Dscr6 14.5dpc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibuya K |
Year: |
2001 |
Journal: |
GenBank Submission |
Title: |
Mus musculus Dscr6 mRNA, mouse homolog of human Down Syndrome critical region gene 6 DSCR6, complete cds |
|
|
Pages: |
AB063284 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawamura A |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators. |
Volume: |
28 |
Issue: |
10 |
Pages: |
3236-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasten E |
Year: |
2018 |
Journal: |
Hum Mol Genet |
Title: |
Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome. |
Volume: |
27 |
Issue: |
11 |
Pages: |
1847-1857 |
|
•
•
•
•
•
|
Publication |
First Author: |
Racedo SE |
Year: |
2017 |
Journal: |
PLoS Genet |
Title: |
Reduced dosage of β-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome. |
Volume: |
13 |
Issue: |
3 |
Pages: |
e1006687 |
|
•
•
•
•
•
|
Publication |
First Author: |
Osipovich AB |
Year: |
2014 |
Journal: |
Development |
Title: |
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. |
Volume: |
141 |
Issue: |
15 |
Pages: |
2939-49 |
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•
•
•
•
•
|
Publication |
First Author: |
Reymond A |
Year: |
2002 |
Journal: |
Nature |
Title: |
Human chromosome 21 gene expression atlas in the mouse. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
582-6 |
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•
•
•
•
•
|
Publication |
First Author: |
Schilling K |
Year: |
2009 |
Journal: |
Cerebellum |
Title: |
The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. |
Volume: |
8 |
Issue: |
4 |
Pages: |
477-89 |
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•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from Europhenome |
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•
•
•
•
•
|
Publication |
First Author: |
Ingham NJ |
Year: |
2019 |
Journal: |
PLoS Biol |
Title: |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
Volume: |
17 |
Issue: |
4 |
Pages: |
e3000194 |
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•
•
•
•
•
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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•
•
•
•
•
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Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
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Title: |
Nomenclature Committee Use |
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•
•
•
•
•
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Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
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2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
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Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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|
•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7786601 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-12-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640115 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:7786650 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression was overlapped with Ripply3 expression, which expanded posteriorly to the 2nd bending site, during the development of the 3rd pharyngeal pouch. |
Specimen Label: |
S3A |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
128
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
201
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kondow A |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis in Xenopus. |
Volume: |
359 |
Issue: |
4 |
Pages: |
959-64 |
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•
•
•
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Publication |
First Author: |
Kondow A |
Year: |
2006 |
Journal: |
Int J Dev Biol |
Title: |
Bowline, a novel protein localized to the presomitic mesoderm, interacts with Groucho/TLE in Xenopus. |
Volume: |
50 |
Issue: |
5 |
Pages: |
473-9 |
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Publication |
First Author: |
Shibuya K |
Year: |
2000 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2. |
Volume: |
271 |
Issue: |
3 |
Pages: |
693-8 |
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Publication |
First Author: |
Hitachi K |
Year: |
2009 |
Journal: |
Int J Dev Biol |
Title: |
The Xenopus Bowline/Ripply family proteins negatively regulate the transcriptional activity of T-box transcription factors. |
Volume: |
53 |
Issue: |
4 |
Pages: |
631-9 |
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Protein Domain |
Type: |
Family |
Description: |
The precise function of this family is not clear, but it is thought to play a role in somitogenesis, development and transcriptional repression []. This family contains two conserved sequence motifs: WRPW and FPVQATI. The WRPW motif is thought to be required for binding to tle/groucho proteins []. Ripply2.2 is also known as Bowline and is an associate protein of the transcriptional co-repressor XGrg-4 []. Ripply3 is also known as Down Syndrome Critical Region Protein 6 homologue []. |
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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