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Search results 101 to 143 out of 143 for Ro60

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Type Details Score
Publication
7799435 | -
First Author: Lin-Marq N
Year: 1995
Journal: J Mol Biol
Title: A yeast RNA binding protein that resembles the human autoantigen La.
Volume: 245
Issue: 2
Pages: 81-5
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Publication
15048103 | -
First Author: Kenan DJ
Year: 2004
Journal: Nat Struct Mol Biol
Title: La gets its wings.
Volume: 11
Issue: 4
Pages: 303-5
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Protein
Q8C4B1
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
Q9D423
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Publication
8035818 | -
First Author: Yoo CJ
Year: 1994
Journal: Mol Cell Biol
Title: La proteins from Drosophila melanogaster and Saccharomyces cerevisiae: a yeast homolog of the La autoantigen is dispensable for growth.
Volume: 14
Issue: 8
Pages: 5412-24
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Protein Domain
IPR006630 | La_HTH
Type: Domain
Description: Human Ro ribonucleoproteins (RNPs) are composed of one of the four small Y RNAs and at least two proteins, Ro60 and La. The La protein is a 47kDa polypeptide that frequently acts as an autoantigen in systemic lupus erythematosus and Sjogren's syndrome []. In the nucleus, La acts as a RNA polymerase III (RNAP III) transcription factor, while in the cytoplasm, La acts as a translation factor []. In the nucleus, La binds to the 3'UTR of nascent RNAP III transcripts to assist in folding and maturation []. In the cytoplasm, La recognises specific classes of mRNAs that contain a 5'-terminal oligopyrimidine (5'TOP) motif known to control protein synthesis []. The specific recognition is mediated by the N-terminal domain of La, which comprises a La motif and a RNA recognition motif (RRM). The La motif adopts an alpha/beta fold that comprises a winged-helix motif [].Homologous La domain-containing proteins have been identified in a wide range of organisms except Archaea, bacteria and viruses [].This domain is found at the N terminus of La RNA-binding proteins as well as other proteins [].
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Protein
Q6ZQ58
Organism: Mus musculus/domesticus
Length: 1072  
Fragment?: false
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Protein
Q3TQS1
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
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Protein
Q3T9Z3
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q8BVS5
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
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Protein
Q3UU34
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: true
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Protein
Z4YJT3
Organism: Mus musculus/domesticus
Length: 1072  
Fragment?: false
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Protein
F6U5V1
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Protein
A0A0A6YWC2
Organism: Mus musculus/domesticus
Length: 335  
Fragment?: false
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Publication
15016896 | -
First Author: Izumi RE
Year: 2004
Journal: J Virol
Title: A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation.
Volume: 78
Issue: 7
Pages: 3763-76
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Publication
14636586 | -
First Author: Intine RV
Year: 2003
Journal: Mol Cell
Title: Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs.
Volume: 12
Issue: 5
Pages: 1301-7
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Publication
14690589 | -
First Author: Keene JD
Year: 2003
Journal: Mol Cell
Title: Posttranscriptional generation of macromolecular complexes.
Volume: 12
Issue: 6
Pages: 1347-9
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Publication
15004549 | -
First Author: Alfano C
Year: 2004
Journal: Nat Struct Mol Biol
Title: Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Volume: 11
Issue: 4
Pages: 323-9
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Protein
Q8BWW4
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Protein
Q6A0A2
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein
E9Q066
Organism: Mus musculus/domesticus
Length: 718  
Fragment?: false
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Protein
G3X9Q6
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Protein
A0A0G2JFW4
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
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Protein
A0A2R8W6Y5
Organism: Mus musculus/domesticus
Length: 610  
Fragment?: false
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Protein
A0A2R8VKL5
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
Q3UT02
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
A2AR07
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
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Protein
D6RI87
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: false
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Protein
Q8BN59
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
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Protein
P32067
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
P97499
Organism: Mus musculus/domesticus
Length: 2629  
Fragment?: false
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Protein
Q8BTU4
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
Q5XKB2
Organism: Mus musculus/domesticus
Length: 2629  
Fragment?: false
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Protein
Q9CYB9
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
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Protein
Q3TG93
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
Q564E6
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
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Protein
F6SXM5
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: true
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Protein
Q8C8C8
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
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Protein
Q8CBL4
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: false
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Protein
A2AMD0
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
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Protein
Q05CL8
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Protein
I3PQW3
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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