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Search results 101 to 200 out of 248 for Rpia

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1781522
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1759722
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1672722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Image: EB2426; Specimen B935
Specimen Label: EB2426; Specimen B935
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274122
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266022
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1624622
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Image: EB2426; Specimen B935
Note: Expression was detected in the digestive system.
Specimen Label: EB2426; Specimen B935
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1646922
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4417093
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5421944
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EB2426; Specimen B935
Detected: false
Specimen Num: 1
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Publication
5360673 | J:322163
First Author: Gumaa KA
Year: 1969
Journal: Biochem J
Title: The pentose phosphate pathway of glucose metabolism. Enzyme profiles and transient and steady-state content of intermediates of alternative pathways of glucose metabolism in Krebs ascites cells.
Volume: 115
Issue: 5
Pages: 1009-29
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Publication
11489994 | J:70821
First Author: Poltorak A
Year: 2001
Journal: J Immunol
Title: A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice.
Volume: 167
Issue: 4
Pages: 2106-11
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Publication
25505152 | J:218247
First Author: Cossette SM
Year: 2014
Journal: Biol Open
Title: Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.
Volume: 4
Issue: 1
Pages: 48-61
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Publication
27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
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Publication
28245920 | J:240028
First Author: Bulusu V
Year: 2017
Journal: Dev Cell
Title: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Volume: 40
Issue: 4
Pages: 331-341.e4
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR004785 | RpiB
Type: Family
Description: Ribose 5-phosphate isomerase () forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. This reaction permits the synthesis of ribose from other sugars, as well as the recycling of sugars from nucleotide breakdown. Two unrelated enzymes can catalyse this reaction: RpiA (found in most organisms) and RpiB (found in some bacteria and eukaryotes). RpiB is also involved in metabolism of the rare sugar, allose, in addition to ribose sugars. The structures of RpiA and RpiB are distinct, RpiB having a Rossmann-type alpha/beta/alpha sandwich topology [].This entry represents the RpiB enzyme. It also includes D-erythrulose-4-phosphate isomerase from Pectobacterium atrosepticum [].
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Publication
12211039 | -
First Author: Rangarajan ES
Year: 2002
Journal: Proteins
Title: Crystal structure of D-ribose-5-phosphate isomerase (RpiA) from Escherichia coli.
Volume: 48
Issue: 4
Pages: 737-40
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Publication
12517338 | -
First Author: Zhang Rg
Year: 2003
Journal: Structure
Title: Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle.
Volume: 11
Issue: 1
Pages: 31-42
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Publication
17196981 | -
First Author: Delarue M
Year: 2007
Journal: J Mol Biol
Title: Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei.
Volume: 366
Issue: 3
Pages: 868-81
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Protein Domain
IPR037171 | NagB/RpiA_transferase-like
Type: Homologous_superfamily
Description: This entry is composed of multiple transferases, mainly ribose-5-phosphate isomerase A (RpiA), glucosamine-6-phosphate deaminase (NagB) and 6-phosphogluconolactonase (6PGL). RpiA and 6PGL are involved in the pentose phosphate pathway while NagB is involved in the last step of the N-acetylneuraminate degradation pathway. These enzymes share a common core α/β structure [].
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Protein
P47968
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Publication
14499611 | -
First Author: Zhang RG
Year: 2003
Journal: J Mol Biol
Title: The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction.
Volume: 332
Issue: 5
Pages: 1083-94
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Publication
29867142 | -
First Author: Carter MS
Year: 2018
Journal: Nat Chem Biol
Title: Functional assignment of multiple catabolic pathways for D-apiose.
Volume: 14
Issue: 7
Pages: 696-705
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Protein Domain
IPR004788 | Ribose5P_isomerase_type_A
Type: Family
Description: Ribose 5-phosphate isomerase, also known as phosphoriboisomerase, catalyses the reversible conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate, the first step in the non-oxidative branch of the pentose phosphate pathway []. This reaction enables ribose to be synthesized from sugars, as well as the recycling of sugars during the degradation of nucleotides. There are two unrelated types of ribose 5-phosphate isomerases: type A (RpiA) is the most common and is found in most organisms, while type B (RpiB) is restricted to specific eukaryotic and prokaryotic species. Escherichia coli produces both RpiA and RpiB (also known as AlsB), although RpiA accounts for 99% of total RPI enzymes []. This entry represents type A (RpiA) enzymes found in eukaryotes (plants, Metazoa and fungi), bacteria and archaea.
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Protein Domain
IPR020672 | Ribose5P_isomerase_typA_subgr
Type: Family
Description: Ribose 5-phosphate isomerase, also known as phosphoriboisomerase, catalyses the reversible conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate, the first step in the non-oxidative branch of the pentose phosphate pathway []. This reaction enables ribose to be synthesized from sugars, as well as the recycling of sugars during the degradation of nucleotides. There are two unrelated types of ribose 5-phosphate isomerases: type A (RpiA) is the most common and is found in most organisms, while type B (RpiB) is restricted to specific eukaryotic and prokaryotic species. Escherichia coli produces both RpiA and RpiB (also known as AlsB), although RpiA accounts for 99% of total RPI enzymes []. This entry represents a subgroup of type A ribose-5-phosphate isomerase that is found in bacteria, archaea and eukaryotes (plants and Metazoa), but excluding those found in fungi.
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Protein Domain
IPR003500 | RpiB_LacA_LacB
Type: Family
Description: This entry represents the sugar isomerase enzymes ribose 5-phosphate isomerase B (RpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB). Galactose-6-phosphate isomerase () is a heteromultimeric protein consisting of subunits LacA and LacB, and catalyses the conversion of D-galactose 6-phosphate to D-tagatose and 6-phosphate in the tagatose 6-phosphate pathway of lactose catabolism []. Galactose-6-phosphate isomerase is induced by galactose or lactose.Ribose 5-phosphate isomerase () forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. This reaction permits the synthesis of ribose from other sugars, as well as the recycling of sugars from nucleotide breakdown. Two unrelated enzymes can catalyse this reaction: RpiA (found in most organisms) and RpiB (found in some bacteria and eukaryotes). RpiB is also involved in metabolism of the rare sugar, allose, in addition to ribose sugars. The structures of RpiA and RpiB are distinct, RpiB having a Rossmann-type alpha/beta/alpha sandwich topology [].
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Protein Domain
IPR036569 | RpiB_LacA_LacB_sf
Type: Homologous_superfamily
Description: This entry represents the sugar isomerase enzymes ribose 5-phosphate isomerase B (RpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB). Galactose-6-phosphate isomerase () is a heteromultimeric protein consisting of subunits LacA and LacB, and catalyses the conversion of D-galactose 6-phosphate to D-tagatose and 6-phosphate in the tagatose 6-phosphate pathway of lactose catabolism []. Galactose-6-phosphate isomerase is induced by galactose or lactose.Ribose 5-phosphate isomerase () forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. This reaction permits the synthesis of ribose from other sugars, as well as the recycling of sugars from nucleotide breakdown. Two unrelated enzymes can catalyse this reaction: RpiA (found in most organisms) and RpiB (found in some bacteria and eukaryotes). RpiB is also involved in metabolism of the rare sugar, allose, in addition to ribose sugars. The structures of RpiA and RpiB are distinct, RpiB having a Rossmann-type alpha/beta/alpha sandwich topology [].
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Protein Domain
IPR035472 | RpiR-like_SIS
Type: Domain
Description: RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, RpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate [].This domain is also found in other members of the RpiR family of transcriptional regulators, such as MurR []and in uncharacterised proteins of the UPF0309 family.
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Publication
8576032 | -
First Author: Sørensen KI
Year: 1996
Journal: J Bacteriol
Title: Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression.
Volume: 178
Issue: 4
Pages: 1003-11
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Publication
1400164 | -
First Author: Rosey EL
Year: 1992
Journal: J Bacteriol
Title: Nucleotide and deduced amino acid sequences of the lacR, lacABCD, and lacFE genes encoding the repressor, tagatose 6-phosphate gene cluster, and sugar-specific phosphotransferase system components of the lactose operon of Streptococcus mutans.
Volume: 174
Issue: 19
Pages: 6159-70
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Publication
14687575 | -
First Author: Roos AK
Year: 2004
Journal: J Mol Biol
Title: Mycobacterium tuberculosis ribose-5-phosphate isomerase has a known fold, but a novel active site.
Volume: 335
Issue: 3
Pages: 799-809
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Publication
18640127 | -
First Author: Roos AK
Year: 2008
Journal: J Mol Biol
Title: D-ribose-5-phosphate isomerase B from Escherichia coli is also a functional D-allose-6-phosphate isomerase, while the Mycobacterium tuberculosis enzyme is not.
Volume: 382
Issue: 3
Pages: 667-79
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Publication
26560079 | -
First Author: Huang H
Year: 2015
Journal: J Am Chem Soc
Title: A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.
Volume: 137
Issue: 46
Pages: 14570-3
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Protein Domain
IPR011860 | Rib-5-P_Isoase_Actino
Type: Family
Description: This family is a member of the RpiB/LacA/LacB family. It includes ribose 5-phosphate isomerases and D-erythrulose-4-phosphate isomerases []. The only candidates for ribose 5-phosphate isomerase in the Actinobacteria are members of this family [, ].Ribose 5-phosphate isomerase () forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. This reaction permits the synthesis of ribose from other sugars, as well as the recycling of sugars from nucleotide breakdown. Two unrelated enzymes can catalyse this reaction: RpiA (found in most organisms) and RpiB (found in some bacteria and eukaryotes).
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Publication
18723630 | -
First Author: Jaeger T
Year: 2008
Journal: J Bacteriol
Title: The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli.
Volume: 190
Issue: 20
Pages: 6598-608
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Protein
Q9CQ60
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
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Protein
Q9D110
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: false
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Protein
Q3TFM8
Organism: Mus musculus/domesticus
Length: 221  
Fragment?: true
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Protein
Q8R1G5
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
Q8CBG6
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
D3Z1R2
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: true
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Protein
Q8QZU3
Organism: Mus musculus/domesticus
Length: 313  
Fragment?: true
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Protein
D6RCJ1
Organism: Mus musculus/domesticus
Length: 48  
Fragment?: false
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Protein
Q8BMC8
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
D3Z0Q4
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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