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Search results 101 to 200 out of 803 for Rptor

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Type Details Score
Publication  
First Author: Fitter S
Year: 2017
Journal: Mol Cell Biol
Title: mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation.
Volume: 37
Issue: 7
Publication
First Author: Gorre N
Year: 2014
Journal: PLoS One
Title: mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility.
Volume: 9
Issue: 10
Pages: e110491
Publication
First Author: Sureshbabu A
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.
Volume: 55
Issue: 5
Pages: 722-735
Publication
First Author: Martin SK
Year: 2018
Journal: Sci Rep
Title: mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis.
Volume: 8
Issue: 1
Pages: 14501
Publication  
First Author: Wang Q
Year: 2021
Journal: Sci Adv
Title: Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling.
Volume: 7
Issue: 27
Publication
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
Publication    
First Author: Tang F
Year: 2017
Journal: Elife
Title: A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice.
Volume: 6
Publication
First Author: Oh WJ
Year: 2010
Journal: EMBO J
Title: mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Volume: 29
Issue: 23
Pages: 3939-51
Publication
First Author: Jacinto E
Year: 2004
Journal: Nat Cell Biol
Title: Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Volume: 6
Issue: 11
Pages: 1122-8
Publication
First Author: Smithson LJ
Year: 2016
Journal: Genes Dev
Title: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Volume: 30
Issue: 12
Pages: 1383-8
Publication
First Author: Partovian C
Year: 2008
Journal: Mol Cell
Title: Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.
Volume: 32
Issue: 1
Pages: 140-9
Publication  
First Author: Serra I
Year: 2022
Journal: Front Mol Neurosci
Title: Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.
Volume: 15
Pages: 831687
Publication
First Author: Zamfirescu RC
Year: 2021
Journal: Am J Physiol Cell Physiol
Title: mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.
Volume: 320
Issue: 1
Pages: C30-C44
Publication  
First Author: Jones I
Year: 2019
Journal: Biol Open
Title: Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction.
Volume: 8
Issue: 8
Publication
First Author: Hasumi Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Volume: 106
Issue: 44
Pages: 18722-7
Publication  
First Author: Haissaguerre M
Year: 2018
Journal: Mol Metab
Title: mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin.
Volume: 12
Pages: 98-106
Publication
First Author: Michon FX
Year: 2023
Journal: Mol Brain
Title: mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons.
Volume: 16
Issue: 1
Pages: 55
Publication
First Author: Lian WS
Year: 2018
Journal: Cell Death Dis
Title: Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR.
Volume: 9
Issue: 10
Pages: 938
Publication
First Author: Khlaifia A
Year: 2022
Journal: Mol Brain
Title: mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination.
Volume: 15
Issue: 1
Pages: 56
Publication
First Author: Bohin N
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury.
Volume: 10
Issue: 4
Pages: 797-810
Publication
First Author: Sun IH
Year: 2018
Journal: J Immunol
Title: mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells.
Volume: 201
Issue: 2
Pages: 481-492
Publication
First Author: Asrani K
Year: 2019
Journal: J Clin Invest
Title: mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation.
Volume: 129
Issue: 12
Pages: 5584-5599
Publication
First Author: Rodriguez Y
Year: 2022
Journal: Liver Res
Title: Liver-adipose tissue crosstalk in alcohol-associated liver disease: The role of mTOR.
Volume: 6
Issue: 4
Pages: 227-237
Publication
First Author: Riahi Y
Year: 2023
Journal: Diabetologia
Title: Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.
Volume: 66
Issue: 10
Pages: 1925-1942
Publication  
First Author: Yamauchi T
Year: 2017
Journal: Mol Cell Biol
Title: FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.
Volume: 37
Issue: 8
Publication
First Author: Cloëtta D
Year: 2013
Journal: J Neurosci
Title: Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis.
Volume: 33
Issue: 18
Pages: 7799-810
Publication
First Author: Magri L
Year: 2011
Journal: Cell Stem Cell
Title: Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.
Volume: 9
Issue: 5
Pages: 447-62
Publication
First Author: Zhu Y
Year: 2013
Journal: PLoS One
Title: Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.
Volume: 8
Issue: 1
Pages: e54221
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Raybuck AL
Year: 2018
Journal: J Immunol
Title: B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.
Volume: 200
Issue: 8
Pages: 2627-2639
Publication
First Author: Polak P
Year: 2008
Journal: Cell Metab
Title: Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.
Volume: 8
Issue: 5
Pages: 399-410
Publication    
First Author: Arriola Apelo SI
Year: 2020
Journal: Elife
Title: Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging.
Volume: 9
Publication  
First Author: Huang W
Year: 2017
Journal: Cell Death Discov
Title: Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway.
Volume: 3
Pages: 16097
Publication  
First Author: Ni Q
Year: 2017
Journal: Nat Commun
Title: Raptor regulates functional maturation of murine beta cells.
Volume: 8
Pages: 15755
Publication  
First Author: Blandino-Rosano M
Year: 2023
Journal: Mol Metab
Title: Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice.
Volume: 75
Pages: 101769
Publication
First Author: Yin Q
Year: 2020
Journal: Nat Commun
Title: Raptor determines β-cell identity and plasticity independent of hyperglycemia in mice.
Volume: 11
Issue: 1
Pages: 2538
Publication
First Author: Reho JJ
Year: 2021
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Vascular effects of disrupting endothelial mTORC1 signaling in obesity.
Volume: 321
Issue: 2
Pages: R228-R237
Publication
First Author: Reho JJ
Year: 2021
Journal: Hypertension
Title: mTORC1 (Mechanistic Target of Rapamycin Complex 1) Signaling in Endothelial and Smooth Muscle Cells Is Required for Vascular Function.
Volume: 77
Issue: 2
Pages: 594-604
Publication
First Author: Xie M
Year: 2022
Journal: Biol Reprod
Title: Loss of Raptor induces Sertoli cells into an undifferentiated state in mice.
Volume: 107
Issue: 4
Pages: 1125-1138
Publication
First Author: Pelgrom LR
Year: 2022
Journal: Cell Rep
Title: mTORC1 signaling in antigen-presenting cells of the skin restrains CD8(+) T cell priming.
Volume: 40
Issue: 1
Pages: 111032
Publication
First Author: Berezhnoy A
Year: 2014
Journal: J Clin Invest
Title: Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity.
Volume: 124
Issue: 1
Pages: 188-97
Publication
First Author: Xiong M
Year: 2017
Journal: FASEB J
Title: Conditional ablation of Raptor in the male germline causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes.
Volume: 31
Issue: 9
Pages: 3934-3949
Publication
First Author: Aladegbami B
Year: 2017
Journal: Sci Rep
Title: Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine.
Volume: 7
Issue: 1
Pages: 5580
Publication
First Author: Onufer EJ
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice.
Volume: 505
Issue: 4
Pages: 1174-1179
Publication  
First Author: Brooks DL
Year: 2020
Journal: Endocrinology
Title: mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner.
Volume: 161
Issue: 5
Publication
First Author: Baraldo M
Year: 2021
Journal: FASEB J
Title: Raptor is critical for increasing the mitochondrial proteome and skeletal muscle force during hypertrophy.
Volume: 35
Issue: 12
Pages: e22031
Publication
First Author: Dey N
Year: 2011
Journal: J Biol Chem
Title: MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes.
Volume: 286
Issue: 29
Pages: 25586-603
Publication
First Author: Hoshii T
Year: 2012
Journal: J Clin Invest
Title: mTORC1 is essential for leukemia propagation but not stem cell self-renewal.
Volume: 122
Issue: 6
Pages: 2114-29
Publication
First Author: Bozadjieva N
Year: 2017
Journal: J Clin Invest
Title: Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.
Volume: 127
Issue: 12
Pages: 4379-4393
Publication
First Author: Yang J
Year: 2016
Journal: Blood
Title: mTORC1 promotes aging-related venous thrombosis in mice via elevation of platelet volume and activation.
Volume: 128
Issue: 5
Pages: 615-24
Publication
First Author: Umemura A
Year: 2014
Journal: Cell Metab
Title: Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.
Volume: 20
Issue: 1
Pages: 133-44
Publication
First Author: Dai DF
Year: 2019
Journal: Geroscience
Title: Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure.
Volume: 41
Issue: 6
Pages: 847-860
Publication
First Author: Chuang JH
Year: 2013
Journal: Stem Cell Res
Title: Differentiation of glutamatergic neurons from mouse embryonic stem cells requires raptor S6K signaling.
Volume: 11
Issue: 3
Pages: 1117-28
Publication  
First Author: Labbé SM
Year: 2016
Journal: Sci Rep
Title: mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold.
Volume: 6
Pages: 37223
Publication
First Author: Ye M
Year: 2021
Journal: Cell Death Dis
Title: CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice.
Volume: 12
Issue: 12
Pages: 1149
Publication
First Author: Guo D
Year: 2024
Journal: Epilepsia
Title: A role of dentate gyrus mechanistic target of rapamycin activation in epileptogenesis in a mouse model of posttraumatic epilepsy.
Volume: 65
Issue: 7
Pages: 2127-2137
Publication
First Author: Xu X
Year: 2022
Journal: EMBO Rep
Title: The mTORC1-eIF4F axis controls paused pluripotency.
Volume: 23
Issue: 2
Pages: e53081
Publication  
First Author: Kim K
Year: 2016
Journal: Nat Commun
Title: mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2.
Volume: 7
Pages: 10255
Publication
First Author: Lu X
Year: 2021
Journal: Am J Pathol
Title: YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice.
Volume: 191
Issue: 9
Pages: 1651-1667
Publication
First Author: You JS
Year: 2019
Journal: FASEB J
Title: The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy.
Volume: 33
Issue: 3
Pages: 4021-4034
Publication
First Author: Norrmén C
Year: 2014
Journal: Cell Rep
Title: mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.
Volume: 9
Issue: 2
Pages: 646-60
Publication
First Author: Steiner JL
Year: 2015
Journal: Alcohol Clin Exp Res
Title: Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction.
Volume: 39
Issue: 1
Pages: 1-10
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2012-02-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5305497
Age: postnatal
Image: 5
Specimen Label: Normal1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2012-02-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5305497
Age: postnatal
Image: 5
Specimen Label: Normal2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2012-02-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5305497
Age: postnatal
Image: 5
Specimen Label: Normal3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2012-02-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5305497
Age: postnatal
Image: 5
Specimen Label: Normal4
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2016-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741220
Stage: TS20
Assay Id: MGI:5806816
Age: embryonic day 12.5
Image: S2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2016-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1741220
Stage: TS20
Assay Id: MGI:5806816
Age: embryonic day 12.5
Image: S2
Specimen Label: RapCKO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:6754093
Age: postnatal adult
Specimen Label: O
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6754093
Age: embryonic day 0.5
Specimen Label: 1C
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6754093
Age: embryonic day 1.0
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:6754093
Age: embryonic day 2.0
Specimen Label: 4C
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6754093
Age: embryonic day 2.5
Specimen Label: 8C
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:6754093
Age: embryonic day 3.0
Specimen Label: MO
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2021-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6754093
Age: embryonic day 3.5
Specimen Label: BL
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914628
Stage: TS28
Assay Id: MGI:7331415
Age: postnatal day 17
Image: S8
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914628
Stage: TS28
Assay Id: MGI:7331415
Age: postnatal day 17
Image: S8
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914628
Stage: TS28
Assay Id: MGI:7331415
Age: postnatal day 17
Image: S8
Specimen Label: KO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5304382
Assay Type: Western blot
Annotation Date: 2022-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914628
Stage: TS28
Assay Id: MGI:7331415
Age: postnatal day 17
Image: S8
Specimen Label: KO
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7548476
Assay Type: Western blot
Annotation Date: 2023-11-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:7548482
Age: embryonic day 14.5
Image: 4
Specimen Label: Inputs
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7548476
Assay Type: Western blot
Annotation Date: 2023-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:1689520
Stage: TS20
Assay Id: MGI:7548527
Age: embryonic day 12.5
Image: 6
Specimen Label: Usp9x<+/Y> 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7548476
Assay Type: Western blot
Annotation Date: 2023-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:1689520
Stage: TS20
Assay Id: MGI:7548527
Age: embryonic day 12.5
Image: 6
Specimen Label: Usp9x<+/Y> 2
Detected: true
Specimen Num: 2