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Search results 101 to 180 out of 180 for Rtcb

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Categories

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
Probe: MGI:7620087
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620151
Age: postnatal adult
Image: 1E Growing GV WT
Note: Expression distributed in nuclei and cytoplasm of oocytes.
Specimen Label: 1E Growing GV WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7620087
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7620151
Age: postnatal adult
Image: 1E Fully Grown GV WT
Note: Expression distributed in nuclei and cytoplasm of oocytes.
Specimen Label: 1E Fully Grown GV WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5817210
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:5817220
Age: embryonic day 3.5
Note: Expression was detected in the cytoplasm of blastomeres in both the inner cell mass and trophectoderm of blastocysts.
Specimen Label: 2B B1-3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5817210
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:5817220
Age: embryonic day 3.5
Note: Expression was detected in the cytoplasm of blastomeres in both the inner cell mass and trophectoderm of blastocysts.
Specimen Label: 2B B1-3
Detected: true
Specimen Num: 1
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Publication
25917546 | J:224688
First Author: Zhang T
Year: 2015
Journal: Stem Cells
Title: Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress.
Volume: 33
Issue: 7
Pages: 2320-30
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Publication
9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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Publication
- | J:29126
     
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: RNA-splicing ligase RtcB homolog
Type: chain
End: 505
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GXD Expression
GXD Expression
   
Probe: MGI:7620023
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620131
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620092
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620145
Age: postnatal adult
Image: 6
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620094
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620147
Age: postnatal adult
Image: 6
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620096
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620148
Age: postnatal adult
Image: 6
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620021
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620132
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620026
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620133
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620025
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620134
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620028
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620135
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620027
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620136
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6305213
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620139
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620089
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620140
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620090
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620141
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620091
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620142
Age: postnatal adult
Image: 4
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6400561
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620144
Age: postnatal adult
Image: 6
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620093
Assay Type: Western blot
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620146
Age: postnatal adult
Image: 6
Specimen Label: Rtcb oo-/-
Detected: true
Specimen Num: 2
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Publication
18508721 | -
 
First Author: Hu J
Year: 2008
Journal: Front Biosci
Title: FAAP, a novel murine protein, is involved in cell adhesion through regulating vinculin-paxillin association.
Volume: 13
Pages: 7123-31
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Publication
21046479 | -
First Author: Ding NZ
Year: 2010
Journal: Endocrine
Title: Expression and regulation of FAAP in the mouse epididymis.
Volume: 38
Issue: 2
Pages: 188-93
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Protein Domain
IPR027513 | RtcB_euk
Type: Family
Description: RctB is a tRNA-splicing ligase from bacteria []. RctB homologues in eukaryotes represent the catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. RctB may act as a RNA ligase with broad substrate specificity, and may function toward other RNAs [].
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GXD Expression
GXD Expression
   
Probe: MGI:7620021
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620108
Age: postnatal adult
Image: 4
Specimen Label: Total Rtcb oo-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7620025
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620109
Age: postnatal adult
Image: 4
Specimen Label: Total Rtcb oo-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7620027
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620110
Age: postnatal adult
Image: 4
Specimen Label: Total Rtcb oo-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7620031
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620111
Age: postnatal adult
Image: 4
Specimen Label: Total Rtcb oo-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7620033
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620112
Age: postnatal adult
Image: 4
Specimen Label: Total Rtcb oo-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7620029
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620113
Age: postnatal adult
Image: 4
Specimen Label: Total Rtcb oo-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7620023
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620114
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620026
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620115
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620028
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620116
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620032
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620117
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620034
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620118
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620030
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620119
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620035
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620120
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620036
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620121
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7620124
Assay Type: RT-PCR
Annotation Date: 2024-04-11
Strength: Present
Sex: Female
Emaps: EMAPS:3570528
Stage: TS28
Assay Id: MGI:7620122
Age: postnatal adult
Image: 4
Specimen Label: IR Rtcb oo-/-
Detected: true
Specimen Num: 2
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Publication
21311021 | -
First Author: Popow J
Year: 2011
Journal: Science
Title: HSPC117 is the essential subunit of a human tRNA splicing ligase complex.
Volume: 331
Issue: 6018
Pages: 760-4
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Protein Domain
IPR018775 | RlaP
Type: Family
Description: This entry represents a group of proteins that belong to the DNA polymerase beta superfamily, with closest affinities to the Minimal Nucleotide Transferase clade (MNT). They are found in diverse RNA repair genome contexts centred on both RtcB and Rnl-type (ATP-grasp fold) repair ligases []. Members of this family of bacterial proteins catalyze the transfer of nucleotide residues from nucleoside diphosphates or triphosphates into dimer or polymer forms.
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HT Experiment
GSE190681 | RNA Ligase RTCB-mediated mRNA Alternative Splicing is Required for Mouse Oocyte Development and Maintenance
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
33930333 | J:314428
First Author: Asanović I
Year: 2021
Journal: Mol Cell
Title: The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Volume: 81
Issue: 12
Pages: 2520-2532.e16
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Publication
25961792 | J:233466
First Author: Song Y
Year: 2015
Journal: Nat Neurosci
Title: Regulation of axon regeneration by the RNA repair and splicing pathway.
Volume: 18
Issue: 6
Pages: 817-25
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Publication
27536007 | -
First Author: Burroughs AM
Year: 2016
Journal: Nucleic Acids Res
Title: RNA damage in biological conflicts and the diversity of responding RNA repair systems.
Volume: 44
Issue: 18
Pages: 8525-8555
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Publication
30355738 | J:270274
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Year: 2018
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Title: The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress.
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First Author: Shibata K
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Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
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Journal: Science
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Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
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