|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 113 out of 113 for Safb2

<< First    < Previous  |  Next >    Last >>
0.02s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
17630952 | -
First Author: Chan CW
Year: 2007
Journal: Biochem J
Title: A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis.
Volume: 407
Issue: 3
Pages: 355-62
•
•
•
•
•
Protein Domain
IPR034780 | SLTM
Type: Family
Description: SLTM belongs to the scaffold attachment factor B (SAFB) family. When overexpressed, it acts as a general inhibitor of transcription that eventually leads to apoptosis [, ].Scaffold attachment factor B (SAFB) family members include SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM. They contain an N-terminal DNA-binding (SAF-A/B, Acinus and PIAS, SAP) domain, an RNA-binding domain (RBD) and an C-terminal arginine/glycine motif RGG/RG domain. Their RGG/RG domain, which partially overlaps with a putative coiled-coil domain, is most conserved and is likely to be involved in protein-protein interactions [].
•
•
•
•
•
Protein
S4R2Q5
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
•
•
•
•
•
Protein
S4R1W0
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: true
•
•
•
•
•
Publication
20014070 | -
First Author: Garee JP
Year: 2010
Journal: J Cell Biochem
Title: SAFB1's multiple functions in biological control-lots still to be done!
Volume: 109
Issue: 2
Pages: 312-9
•
•
•
•
•
Protein Domain
IPR034781 | SAFB1
Type: Family
Description: SAFB1 belongs to the scaffold attachment factor B (SAFB) family. It has many functions such as transcriptional repression and RNA splicing. It may also have a role in chromatin organization. It is involved in in numerous cellular processes including cell growth, stress response, and apoptosis []. It plays an important role in cancer, particularly in breast tumorigenesis []. Scaffold attachment factor B (SAFB) family members include SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM. They contain an N-terminal DNA-binding (SAF-A/B, Acinus and PIAS, SAP) domain, an RNA-binding domain (RBD) and an C-terminal arginine/glycine motif RGG/RG domain. Their RGG/RG domain, which partially overlaps with a putative coiled-coil domain, is most conserved and is likely to be involved in protein-protein interactions [].
•
•
•
•
•
Protein
Q9CS69
Organism: Mus musculus/domesticus
Length: 374  
Fragment?: true
•
•
•
•
•
Protein
A0A1L1SRL0
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: false
•
•
•
•
•
Protein
Q8CH25
Organism: Mus musculus/domesticus
Length: 1031  
Fragment?: false
•
•
•
•
•
Protein
D3YXK2
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: false
•
•
•
•
•
Protein
S4R1M2
Organism: Mus musculus/domesticus
Length: 939  
Fragment?: false
•
•
•
•
•
Protein
A0A1L1STF9
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
•
•
•
•
•
Protein
B9EI57
Organism: Mus musculus/domesticus
Length: 1031  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom