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Search results 101 to 200 out of 257 for Sec1

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Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
Allele    
Name: Sec1 family domain containing 1; wild type
Allele    
Name: Sec1 family domain containing 2; wild type
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_16
Specimen Label: euxassay_014266_16
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_17
Specimen Label: euxassay_014266_17
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_18
Specimen Label: euxassay_014266_18
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_19
Specimen Label: euxassay_014266_19
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_20
Specimen Label: euxassay_014266_20
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_21
Specimen Label: euxassay_014266_21
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_22
Specimen Label: euxassay_014266_22
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_23
Specimen Label: euxassay_014266_23
Detected: true
Specimen Num: 8
Allele  
Name: Sec1 family domain containing 2; gene trap CSH331, BayGenomics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap TEA105, BayGenomics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap OST306, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap OST819, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap OST3950, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap OST9114, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap OST24568, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 2; gene trap OST128587, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 1; gene trap OST177875, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 1; gene trap OST290775, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 1; gene trap OST332362, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Sec1 family domain containing 1; gene trap OST422824, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: Sec1 family domain containing 2; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Interaction Experiment
Description: A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells.
Allele
Name: secretory blood group 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Bracher A
Year: 2000
Journal: Structure
Title: The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Volume: 8
Issue: 7
Pages: 685-94
Allele  
Name: Sec1 family domain containing 1; gene trap AC0265, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Allele
Name: Sec1 family domain containing 1; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: Sec1 family domain containing 1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: Sec1 family domain containing 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Genotype
Symbol: Scfd2/Scfd2
Background: C57BL/6NJ-Scfd2/Mmjax
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Seals DF
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion.
Volume: 97
Issue: 17
Pages: 9402-7
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Scfd1/Scfd1
Background: C57BL/6N-Scfd1/Cmmr
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Scfd1/Scfd1<+>
Background: C57BL/6N-Scfd1/Cmmr
Zygosity: ht
Has Mutant Allele: true
Allele
Name: fucosyltransferase 1; targeted mutation 1, Dapeng Zhou
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: deletion, Chr 7, Dapeng Zhou
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Poussu E
Year: 2005
Journal: Nucleic Acids Res
Title: A gene truncation strategy generating N- and C-terminal deletion variants of proteins for functional studies: mapping of the Sec1p binding domain in yeast Mso1p by a Mu in vitro transposition-based approach.
Volume: 33
Issue: 12
Pages: e104
Publication
First Author: Knop M
Year: 2005
Journal: Mol Biol Cell
Title: Molecular interactions position Mso1p, a novel PTB domain homologue, in the interface of the exocyst complex and the exocytic SNARE machinery in yeast.
Volume: 16
Issue: 10
Pages: 4543-56
Protein Domain
Type: Domain
Description: Mso1 is a probable component of the secretory vesicle docking complex. It interacts with Sec1, which is a Sm-like protein involved in docking and fusion of exocytic vesicles []. The Sec1 binding domain has been identified in the N-terminal region of Mso1 []. This entry represents the N-terminal region (including the Sec1 binding domain) of Mso1.
Allele
Name: netrin 5; targeted mutation 1, Robert W Burgess
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: netrin 5; targeted mutation 1.1, Robert W Burgess
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Ntn5/Ntn5
Background: STOCK Ntn5/Rwb
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ntn5/Ntn5<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Gissen P
Year: 2005
Journal: Hum Mol Genet
Title: Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights.
Volume: 14
Issue: 10
Pages: 1261-70
Protein
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
Protein Domain
Type: Family
Description: Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion [].
Protein Domain
Type: Homologous_superfamily
Description: Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].This superfamily represents the N-terminal region of domain 3 (called domain 3a) found in Sec1 and related proteins.
Protein Domain
Type: Homologous_superfamily
Description: Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].This superfamily represents the domain 1 of Sec1 and related proteins.
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true