Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
597
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
390
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
51
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; wild type |
|
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; wild type |
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_16 |
|
Specimen Label: |
euxassay_014266_16 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_17 |
|
Specimen Label: |
euxassay_014266_17 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_18 |
|
Specimen Label: |
euxassay_014266_18 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_19 |
|
Specimen Label: |
euxassay_014266_19 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_20 |
|
Specimen Label: |
euxassay_014266_20 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_21 |
|
Specimen Label: |
euxassay_014266_21 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_22 |
|
Specimen Label: |
euxassay_014266_22 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4426900 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774323 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4827893 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_014266_23 |
|
Specimen Label: |
euxassay_014266_23 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap CSH331, BayGenomics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap TEA105, BayGenomics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap OST306, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap OST819, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap OST3950, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap OST9114, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap OST24568, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; gene trap OST128587, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; gene trap OST177875, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; gene trap OST290775, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; gene trap OST332362, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; gene trap OST422824, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 2; endonuclease-mediated mutation 1, Jackson |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells. |
|
•
•
•
•
•
|
Allele |
Name: |
secretory blood group 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Bracher A |
Year: |
2000 |
Journal: |
Structure |
Title: |
The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis. |
Volume: |
8 |
Issue: |
7 |
Pages: |
685-94 |
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; gene trap AC0265, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
Sec1 family domain containing 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Scfd2/Scfd2 |
Background: |
C57BL/6NJ-Scfd2/Mmjax |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Seals DF |
Year: |
2000 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. |
Volume: |
97 |
Issue: |
17 |
Pages: |
9402-7 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Scfd1/Scfd1 |
Background: |
C57BL/6N-Scfd1/Cmmr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Scfd1/Scfd1<+> |
Background: |
C57BL/6N-Scfd1/Cmmr |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
fucosyltransferase 1; targeted mutation 1, Dapeng Zhou |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
deletion, Chr 7, Dapeng Zhou |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Poussu E |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
A gene truncation strategy generating N- and C-terminal deletion variants of proteins for functional studies: mapping of the Sec1p binding domain in yeast Mso1p by a Mu in vitro transposition-based approach. |
Volume: |
33 |
Issue: |
12 |
Pages: |
e104 |
|
•
•
•
•
•
|
Publication |
First Author: |
Knop M |
Year: |
2005 |
Journal: |
Mol Biol Cell |
Title: |
Molecular interactions position Mso1p, a novel PTB domain homologue, in the interface of the exocyst complex and the exocytic SNARE machinery in yeast. |
Volume: |
16 |
Issue: |
10 |
Pages: |
4543-56 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Mso1 is a probable component of the secretory vesicle docking complex. It interacts with Sec1, which is a Sm-like protein involved in docking and fusion of exocytic vesicles []. The Sec1 binding domain has been identified in the N-terminal region of Mso1 []. This entry represents the N-terminal region (including the Sec1 binding domain) of Mso1. |
|
•
•
•
•
•
|
Allele |
Name: |
netrin 5; targeted mutation 1, Robert W Burgess |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
netrin 5; targeted mutation 1.1, Robert W Burgess |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ntn5/Ntn5 |
Background: |
STOCK Ntn5/Rwb |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ntn5/Ntn5<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Gissen P |
Year: |
2005 |
Journal: |
Hum Mol Genet |
Title: |
Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. |
Volume: |
14 |
Issue: |
10 |
Pages: |
1261-70 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
477
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
80
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].This superfamily represents the N-terminal region of domain 3 (called domain 3a) found in Sec1 and related proteins. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Homologous_superfamily |
Description: |
Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].This superfamily represents the domain 1 of Sec1 and related proteins. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
101
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
146
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
100
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
119
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
164
 |
Fragment?: |
true |
|
•
•
•
•
•
|