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Search results 101 to 200 out of 257 for Sec1

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Hits by Pathway

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Hits by Strain

Type Details Score
Protein
Q8BRF7-3
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
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Protein
Q8BRF7-2
Organism: Mus musculus/domesticus
Length: 390  
Fragment?: false
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Protein
A0A0J9YVF7
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
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Allele
Scfd1<+> | MGI:3049508
   
Name: Sec1 family domain containing 1; wild type
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Allele
Scfd2<+> | MGI:3049509
   
Name: Sec1 family domain containing 2; wild type
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Protein Coding Gene
MGP_CAROLIEiJ_G0017734 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_CAROLIEiJ_G0027303 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0029632 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019656 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029548 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019663 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1924233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030063 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019019 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028740 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029301 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029407 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029532 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030096 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018786 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028820 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017084 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_PahariEiJ_G0029490 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018580 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein Coding Gene
MGP_SPRETEiJ_G0028298 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_16
Specimen Label: euxassay_014266_16
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_17
Specimen Label: euxassay_014266_17
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_18
Specimen Label: euxassay_014266_18
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_19
Specimen Label: euxassay_014266_19
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_20
Specimen Label: euxassay_014266_20
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_21
Specimen Label: euxassay_014266_21
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_22
Specimen Label: euxassay_014266_22
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:4426900
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1774323
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827893
Age: embryonic day 14.5
Image: euxassay_014266_23
Specimen Label: euxassay_014266_23
Detected: true
Specimen Num: 8
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Allele
Scfd2<Gt(CSH331)Byg> | MGI:3878684
 
Name: Sec1 family domain containing 2; gene trap CSH331, BayGenomics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(TEA105)Byg> | MGI:4128615
 
Name: Sec1 family domain containing 2; gene trap TEA105, BayGenomics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(OST306)Lex> | MGI:4131192
 
Name: Sec1 family domain containing 2; gene trap OST306, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(OST819)Lex> | MGI:4131569
 
Name: Sec1 family domain containing 2; gene trap OST819, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(OST3950)Lex> | MGI:4133730
 
Name: Sec1 family domain containing 2; gene trap OST3950, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(OST9114)Lex> | MGI:4136925
 
Name: Sec1 family domain containing 2; gene trap OST9114, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(OST24568)Lex> | MGI:4146718
 
Name: Sec1 family domain containing 2; gene trap OST24568, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd2<Gt(OST128587)Lex> | MGI:4196407
 
Name: Sec1 family domain containing 2; gene trap OST128587, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd1<Gt(OST177875)Lex> | MGI:4217100
 
Name: Sec1 family domain containing 1; gene trap OST177875, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd1<Gt(OST290775)Lex> | MGI:4267161
 
Name: Sec1 family domain containing 1; gene trap OST290775, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd1<Gt(OST332362)Lex> | MGI:4283320
 
Name: Sec1 family domain containing 1; gene trap OST332362, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd1<Gt(OST422824)Lex> | MGI:4312087
 
Name: Sec1 family domain containing 1; gene trap OST422824, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Scfd2<em1(IMPC)J> | MGI:6293920
Name: Sec1 family domain containing 2; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Katagiri H (1995)
Description: A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells.
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Allele
Sec1<em1Smoc> | MGI:7292203
Name: secretory blood group 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
10903948 | -
First Author: Bracher A
Year: 2000
Journal: Structure
Title: The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis.
Volume: 8
Issue: 7
Pages: 685-94
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Allele
Scfd1<Gt(AC0265)Wtsi> | MGI:4331225
 
Name: Sec1 family domain containing 1; gene trap AC0265, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Scfd1<tm1e(EUCOMM)Hmgu> | MGI:4461514
Name: Sec1 family domain containing 1; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Scfd1<tm1a(EUCOMM)Hmgu> | MGI:4461535
Name: Sec1 family domain containing 1; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:6293921 | C57BL/6NJ-Scfd2<em1(IMPC)J>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Scfd1<em1(IMPC)Tcp> | MGI:6383384
Name: Sec1 family domain containing 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Scfd2/Scfd2
Background: C57BL/6NJ-Scfd2/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Publication
10944212 | -
First Author: Seals DF
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion.
Volume: 97
Issue: 17
Pages: 9402-7
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Strain
MGI:6429519 | C57BL/6JSmoc-Sec1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6492524 | C57BL/6N-Scfd1<em1(IMPC)Tcp>/Cmmr
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6866578 | C57BL/6NCrl-Scfd1<em1(IMPC)Tcp>/TcpMmucd
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Scfd1/Scfd1
Background: C57BL/6N-Scfd1/Cmmr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Scfd1/Scfd1<+>
Background: C57BL/6N-Scfd1/Cmmr
Zygosity: ht
Has Mutant Allele: true
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Allele
Fut1<tm1Dzhou> | MGI:6358187
Name: fucosyltransferase 1; targeted mutation 1, Dapeng Zhou
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Del(7Fut2-Sec1)1Dzhou | MGI:6358189
Name: deletion, Chr 7, Dapeng Zhou
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
16006618 | -
First Author: Poussu E
Year: 2005
Journal: Nucleic Acids Res
Title: A gene truncation strategy generating N- and C-terminal deletion variants of proteins for functional studies: mapping of the Sec1p binding domain in yeast Mso1p by a Mu in vitro transposition-based approach.
Volume: 33
Issue: 12
Pages: e104
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Publication
16030256 | -
First Author: Knop M
Year: 2005
Journal: Mol Biol Cell
Title: Molecular interactions position Mso1p, a novel PTB domain homologue, in the interface of the exocyst complex and the exocytic SNARE machinery in yeast.
Volume: 16
Issue: 10
Pages: 4543-56
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Protein Domain
IPR028095 | Mso1_N_dom
Type: Domain
Description: Mso1 is a probable component of the secretory vesicle docking complex. It interacts with Sec1, which is a Sm-like protein involved in docking and fusion of exocytic vesicles []. The Sec1 binding domain has been identified in the N-terminal region of Mso1 []. This entry represents the N-terminal region (including the Sec1 binding domain) of Mso1.
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Allele
Ntn5<tm1Rwb> | MGI:5695252
Name: netrin 5; targeted mutation 1, Robert W Burgess
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ntn5<tm1.1Rwb> | MGI:5701693
Name: netrin 5; targeted mutation 1.1, Robert W Burgess
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:5701708 | STOCK Ntn5<tm1.1Rwb>/Rwb
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Ntn5/Ntn5
Background: STOCK Ntn5/Rwb
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ntn5/Ntn5<+>
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: ht
Has Mutant Allele: true
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Publication
15790593 | J:99274
First Author: Gissen P
Year: 2005
Journal: Hum Mol Genet
Title: Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights.
Volume: 14
Issue: 10
Pages: 1261-70
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Protein
Q3TR67
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: false
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Protein
S4R227
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
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Protein Domain
IPR001619 | Sec1-like
Type: Family
Description: Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion [].
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Protein Domain
IPR043127 | Sec-1-like_dom3a
Type: Homologous_superfamily
Description: Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].This superfamily represents the N-terminal region of domain 3 (called domain 3a) found in Sec1 and related proteins.
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Protein Domain
IPR043154 | Sec-1-like_dom1
Type: Homologous_superfamily
Description: Members of the Sec1 family include Sec1, Sly1, Slp1/Vps33, Vps45/Stt10 (yeast), Unc-18 (nematode), Munc-18b/muSec1, Munc-18c (mouse), Rop (Drosophila), Munc-18/n-Sec1/rbSec1A and rbSec1B (rat) [].Sec1-like molecules have been implicated in a variety of eukaryotic vesicle transport processes including neurotransmitter release by exocytosis [].They regulate vesicle transport by binding to a t-SNARE from the syntaxin family. This process is thought to prevent SNARE complex formation, a protein complex required for membrane fusion. Whereas Sec1 molecules are essential for neurotransmitter release and other secretory events, their interaction with syntaxin molecules seems to represent a negative regulatory step in secretion []. The nSec1 polypeptide chain can be divided into three domains. The first domain, consists of a five-stranded parallel β-sheet flanked by five α-helices. The second domain, like the first one, has an α-β-alpha fold, however the β-sheet of domain 2 features five parallel strands with an additional antiparallel strand on one edge. The third domain is a large insertion between the third and fourth parallel strands of domain 2, and can be subdivided in two [].This superfamily represents the domain 1 of Sec1 and related proteins.
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Protein
A2AEC9
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
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Protein
A0A0G2JEQ3
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
A0A140LHJ4
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: true
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Protein
A0A140LJH9
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
Q6ZQ26
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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